■食管静脉曲张的发展是肝硬化的主要并发症之一,内窥镜检查用于观察存在,分级,和食管静脉曲张的长期监测,这是一个侵入性和令人不快的过程。没有足够的数据表明非侵入性方法可以用于相同的方法。
■70名肝硬化患者参加了这项研究。门静脉直径等因素,脾脏大小,血小板计数,血清胆红素,Child-Pugh评分,凝血酶原时间(PT),观察和PTINR,并在所有患者的内镜下与食管静脉曲张的存在和分级相关。
■血小板计数,门静脉直径,血清胆红素,脾双极直径,PT与静脉曲张的存在具有统计学意义的相关性。其中,血小板计数,门静脉直径,血清胆红素与静脉曲张分级也有统计学意义的相关性。监测这些非侵入性参数可以帮助监测静脉曲张生长。
■非侵入性参数可有效用于预测食管静脉曲张的存在和分级,同时将未诊断的静脉曲张发生率保持在可接受的低水平。通过使用非侵入性参数,患者可以通过减少重复内镜评估的需求而受益,这是一种令人不快的过程,并且可用性也受到限制.
UNASSIGNED: Development of esophageal varices is one of the major complications of liver cirrhosis, and endoscopy is used to see the presence, grading, and long-term monitoring of esophageal varices which is an invasive and unpleasant procedure. There is no adequate data available showing noninvasive methods can be used for the same.
UNASSIGNED: Seventy patients with liver cirrhosis participated in the study. Factors like portal vein diameter, spleen size, platelet count, serum bilirubin, Child-Pugh score, prothrombin time (PT), and PT INR were observed and correlated endoscopically with the presence and grading of esophageal varices in all patients.
UNASSIGNED: The platelet count, portal vein diameter, serum bilirubin, spleen bipolar diameter, and PT had statistically significant correlations with the presence of varices. Among them, platelet count, portal vein diameter, and serum bilirubin also had statistically significant correlations with the grading of varices. Monitoring of these noninvasive parameters can help in monitoring variceal growth.
UNASSIGNED: Noninvasive parameters can be used effectively to predict the presence and grading of esophageal varices and at the same time keep the rate of undiagnosed varices acceptably low. By using noninvasive parameters, patients can be benefited by decreasing the requirement of repeated endoscopic evaluation which is an unpleasant procedure and availability is also limited.