UNASSIGNED: This study was conducted on 64 subjects with sonographic features of chronic liver disease who were referred for routine follow-up scans. Portal vein diameter, average velocity, splenic index, congestion index (CI), and portal vein area and velocity were measured.
UNASSIGNED: Subjects with gastroesophageal varices had significantly larger portal vein diameters (14.7±1.64 mm) compared to those without varices (12.05±1.26 mm) (P<0.05). Conversely, subjects without varices exhibited a higher portal vein velocity of (17.9±0.6 cm/s) than with varices (13.91±2.01 cm/s) (P=0.0005). The splenic index was higher in subjects with varices (1120±494 cm3) than those without varices (419 cm3) (P<0.05). The CI was also higher in subjects with varices. Portal vein velocity showed the highest sensitivity (94%) with a cutoff of 19 cm/s, while the CI had the highest diagnostic accuracy (93.75%) with a cutoff of 0.10 cm xsec. The splenic index demonstrated a sensitivity of 92.85% and diagnostic accuracy of 92.18% with a cutoff of 480 cm3. The splenic index followed by the CI is found to be a better predictor of esophageal varices (area under the curve of 96.8 and 96%, respectively).
UNASSIGNED: Ultrasonographic assessment of the portal vein and spleen is a reliable, noninvasive method for predicting gastroesophageal varices in liver cirrhosis. The splenic index and CI have high diagnostic accuracy.
■这项研究是对64名具有慢性肝病超声特征的受试者进行的,这些受试者被推荐进行常规随访扫描。门静脉直径,平均速度,脾指数,拥塞指数(CI),并测量门静脉面积和速度。
■患有胃食管静脉曲张的受试者的门静脉直径(14.7±1.64mm)明显大于没有静脉曲张的受试者(12.05±1.26mm)(P<0.05)。相反,无静脉曲张者门静脉流速(17.9±0.6cm/s)高于有静脉曲张者(13.91±2.01cm/s)(P=0.0005)。有静脉曲张者脾指数(1120±494cm3)高于无静脉曲张者(419cm3)(P<0.05)。TheCI在静脉曲张患者中也较高。门静脉速度显示最高的灵敏度(94%),截止值为19cm/s,而CI的诊断准确率最高(93.75%),截断值为0.10cmxsec.脾指数的灵敏度为92.85%,诊断准确率为92.18%,临界值为480cm3。发现脾指数其次是CI是食管静脉曲张的更好预测指标(曲线下面积为96.8%和96%,分别)。
■门静脉和脾脏的超声检查是可靠的,无创性预测肝硬化食管静脉曲张的方法。脾指数和CI具有较高的诊断准确性。