PDF(Pubmed)
Abstract：
UNASSIGNED: Esophageal and gastric fundic varices are common in liver cirrhosis patients. Ultrasound with the Doppler study assesses liver cirrhosis severity, measuring portal vein and splenic indices\' association with gastroesophageal varices.
UNASSIGNED: This study was conducted on 64 subjects with sonographic features of chronic liver disease who were referred for routine follow-up scans. Portal vein diameter, average velocity, splenic index, congestion index (CI), and portal vein area and velocity were measured.
UNASSIGNED: Subjects with gastroesophageal varices had significantly larger portal vein diameters (14.7±1.64 mm) compared to those without varices (12.05±1.26 mm) (P<0.05). Conversely, subjects without varices exhibited a higher portal vein velocity of (17.9±0.6 cm/s) than with varices (13.91±2.01 cm/s) (P=0.0005). The splenic index was higher in subjects with varices (1120±494 cm3) than those without varices (419 cm3) (P<0.05). The CI was also higher in subjects with varices. Portal vein velocity showed the highest sensitivity (94%) with a cutoff of 19 cm/s, while the CI had the highest diagnostic accuracy (93.75%) with a cutoff of 0.10 cm xsec. The splenic index demonstrated a sensitivity of 92.85% and diagnostic accuracy of 92.18% with a cutoff of 480 cm3. The splenic index followed by the CI is found to be a better predictor of esophageal varices (area under the curve of 96.8 and 96%, respectively).
UNASSIGNED: Ultrasonographic assessment of the portal vein and spleen is a reliable, noninvasive method for predicting gastroesophageal varices in liver cirrhosis. The splenic index and CI have high diagnostic accuracy.
UNASSIGNED: This study was conducted on 64 subjects with sonographic features of chronic liver disease who were referred for routine follow-up scans. Portal vein diameter, average velocity, splenic index, congestion index (CI), and portal vein area and velocity were measured.
UNASSIGNED: Subjects with gastroesophageal varices had significantly larger portal vein diameters (14.7±1.64 mm) compared to those without varices (12.05±1.26 mm) (P<0.05). Conversely, subjects without varices exhibited a higher portal vein velocity of (17.9±0.6 cm/s) than with varices (13.91±2.01 cm/s) (P=0.0005). The splenic index was higher in subjects with varices (1120±494 cm3) than those without varices (419 cm3) (P<0.05). The CI was also higher in subjects with varices. Portal vein velocity showed the highest sensitivity (94%) with a cutoff of 19 cm/s, while the CI had the highest diagnostic accuracy (93.75%) with a cutoff of 0.10 cm xsec. The splenic index demonstrated a sensitivity of 92.85% and diagnostic accuracy of 92.18% with a cutoff of 480 cm3. The splenic index followed by the CI is found to be a better predictor of esophageal varices (area under the curve of 96.8 and 96%, respectively).
UNASSIGNED: Ultrasonographic assessment of the portal vein and spleen is a reliable, noninvasive method for predicting gastroesophageal varices in liver cirrhosis. The splenic index and CI have high diagnostic accuracy.
摘要：
■食管和胃底静脉曲张在肝硬化患者中很常见。超声与多普勒研究评估肝硬化的严重程度，测量门静脉和脾指数与胃食管静脉曲张的相关性。
■这项研究是对64名具有慢性肝病超声特征的受试者进行的，这些受试者被推荐进行常规随访扫描。门静脉直径，平均速度,脾指数,拥塞指数(CI)，并测量门静脉面积和速度。
■患有胃食管静脉曲张的受试者的门静脉直径（14.7±1.64mm）明显大于没有静脉曲张的受试者（12.05±1.26mm）（P<0.05）。相反，无静脉曲张者门静脉流速(17.9±0.6cm/s)高于有静脉曲张者(13.91±2.01cm/s)(P=0.0005)。有静脉曲张者脾指数(1120±494cm3)高于无静脉曲张者(419cm3)(P<0.05)。TheCI在静脉曲张患者中也较高。门静脉速度显示最高的灵敏度（94％），截止值为19cm/s，而CI的诊断准确率最高(93.75%),截断值为0.10cmxsec.脾指数的灵敏度为92.85％，诊断准确率为92.18％，临界值为480cm3。发现脾指数其次是CI是食管静脉曲张的更好预测指标（曲线下面积为96.8％和96％，分别)。
■门静脉和脾脏的超声检查是可靠的，无创性预测肝硬化食管静脉曲张的方法。脾指数和CI具有较高的诊断准确性。
■这项研究是对64名具有慢性肝病超声特征的受试者进行的，这些受试者被推荐进行常规随访扫描。门静脉直径，平均速度,脾指数,拥塞指数(CI)，并测量门静脉面积和速度。
■患有胃食管静脉曲张的受试者的门静脉直径（14.7±1.64mm）明显大于没有静脉曲张的受试者（12.05±1.26mm）（P<0.05）。相反，无静脉曲张者门静脉流速(17.9±0.6cm/s)高于有静脉曲张者(13.91±2.01cm/s)(P=0.0005)。有静脉曲张者脾指数(1120±494cm3)高于无静脉曲张者(419cm3)(P<0.05)。TheCI在静脉曲张患者中也较高。门静脉速度显示最高的灵敏度（94％），截止值为19cm/s，而CI的诊断准确率最高(93.75%),截断值为0.10cmxsec.脾指数的灵敏度为92.85％，诊断准确率为92.18％，临界值为480cm3。发现脾指数其次是CI是食管静脉曲张的更好预测指标（曲线下面积为96.8％和96％，分别)。
■门静脉和脾脏的超声检查是可靠的，无创性预测肝硬化食管静脉曲张的方法。脾指数和CI具有较高的诊断准确性。
