坏疽性脓皮病(PG)是一种极为罕见的无菌性坏死性溃疡性疾病,与营养不良作为易感因素有关。不清楚,虽然,是否扩张型心肌病,影响血液流动并导致动脉狭窄,可以作为病因发挥作用。在这项研究中,一例10岁男孩坏疽性脓皮病并发扩张型心肌病,既往有脑血管疾病史,据报道营养不良。据报道,该患者的双腿均有渗出性坏死病变。病变开始时很小,多个,两条腿上有发痒的病变,后来变成了水泡和磨损,进展到痛苦,脓液脱落的病变,出血,病变周围发红,一个月内就会有虫.高烧是伴随的症状。多学科团队参与为该患者提供综合治疗。多次进行抗生素和坏死性清创术。抗凝治疗表明凝血标志物增加,超声心动图提示左心室有血栓。应纠正增加坏疽性脓皮病风险的潜在疾病。病人经临床好转后出院,尽管需要继续门诊监测.我们的报告表明,影响正常血流的扩张型心肌病的慢性病会导致营养不良,血栓的形成,和外周动脉狭窄,所有这些都导致了坏疽性脓皮病。因此,早期手术治疗,抗生素管理,建议抗凝治疗。
Pyoderma gangrenosum (PG) is an extremely rare case of sterile necrotic ulcerative disease associated with malnutrition as a predisposition factor. It is unclear, though, whether dilated cardiomyopathy, which affects blood flow and results in stenosis in the arteries, could play a role as an etiology. In this study, a case of pyoderma gangrenosum in a 10-year-old boy complicated by dilated cardiomyopathy, a previous history of cerebrovascular disease, and a malnourished condition were reported. The patient was reported to have exudative necrotic lesions in both legs. Lesions began as small, multiple, itchy lesions on both legs, which later became blisters and scuffed, and progressed into painful, peeled-off lesions with pus, bleeding, redness around lesions, and maggots within a month. A high fever was an accompanying symptom. The multidisciplinary team was involved to provide a comprehensive treatment for this patient. Antibiotics and necrotomy debridement were performed several times. Anticoagulant treatment was indicated as the coagulation markers were increased and echocardiography suggested thrombus in the left ventricle. The underlying condition that increases the risk of pyoderma gangrenosum should be corrected. The patient was discharged after a clinical improvement, although the continuation of outpatient monitoring was required. Our report suggests that a chronic condition of dilated cardiomyopathy that affects normal blood flow leads to malnutrition, the formation of thrombus, and stenosis of a peripheral artery, all of which contributed to pyoderma gangrenosum. Therefore, early surgical treatment, antibiotic administration, and anticoagulant treatment were recommended.