meditation

冥想
  • 文章类型: Journal Article
    接受手术的患者,特别是接受肿瘤诊断手术的患者,体验焦虑。手术仍然是许多常见类型癌症的主要治疗方法。在术前和术后缓解焦虑的一个有希望的潜在干预措施是冥想,综合医学干预。然而,在围手术期冥想缓解焦虑的有效性方面,文献仍存在空白.
    范围审查是使用Arksey和O\'Malley框架进行的,以综合研究结果,并与系统审查的首选报告项目和范围审查的Meta分析扩展(PRISMA-ScR)一起报告。审查包括EMBASE,PubMed,WebofScience,CINAHLPlus,Scopus,和2013年至2024年的CochraneReview数据库。所有已识别的文章都输出到在线系统审查软件,Covidence.
    总共确定了538篇初始引文,筛选了415个标题和摘要,审查了83篇全文。最终纳入了六项研究。从文献中提取的数据包括:研究目的,研究设计,样本量,术前或术后时间范围,评估焦虑的工具,和结论。
    对于接受肿瘤外科手术的患者,围手术期可以充满焦虑。引导,正念,慈爱冥想可能有助于减少焦虑,特别是在术后接受乳腺癌手术的患者中。然而,目前的文献极为有限。未来的研究应将初步有效性扩展到更广泛的人群,并仔细针对最高风险人群的理想干预时间点。
    UNASSIGNED: Patients undergoing surgery, particularly patients undergoing surgery for oncology diagnoses, experience anxiety. Surgery remains the primary treatment for many common types of cancer. One promising potential intervention to alleviate anxiety in the preoperative and postoperative period is meditation, an integrative medicine intervention. However, there remains a gap in the literature regarding the effectiveness of meditation to alleviate anxiety during the perioperative time period.
    UNASSIGNED: The scoping review was conducted using the Arksey and O\'Malley framework to synthesize the study findings and was reported with the Preferred Reporting Items for Systematic reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR). The review included EMBASE, PubMed, Web of Science, CINAHL Plus, Scopus, and Cochrane Review databases from 2013 through 2024. All identified articles were exported to the online systematic review software, Covidence.
    UNASSIGNED: A total of 538 initial citations were identified, 415 titles and abstracts were screened, and 83 full-text articles reviewed. Six studies were finally included. The data extracted from the literature included: study purpose, study design, sample size, preoperative or postoperative timeframe, instrument to evaluate anxiety, and conclusions.
    UNASSIGNED: For patients undergoing oncology surgery, the perioperative period can be filled with anxiety. Guided, mindfulness, and loving-kindness meditation may be helpful in reducing anxiety, particularly in patients undergoing surgery for breast cancer during the postoperative period. However, the current literature is extremely limited. Future research should expand on the preliminary effectiveness to broader populations and carefully target the highest-risk populations for the ideal time point for interventions.
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  • 文章类型: Journal Article
    冥想,迷幻药,以及其他可以调节意识体验的类似实践或归纳方法,在临床和非临床环境中越来越受欢迎。与这种实践或模式相关的现象学是巨大的。据报道,许多类似的效果和经验也是自发发生的。我们认为,这种经验范围在当代文学中仍然没有得到充分描述或理解,并且有更广泛的研究它的伦理授权,从全面的文档和定义开始。我们回顾了50篇最近的临床或科学出版物,以评估现象的范围,经验,影响,后遗症,以及与各种精神活性化合物相关的影响,冥想练习,以及其他方式或事件。这导致了一个大的清单,综合了30,000多个个体受试者的报告。然后,我们批判性地讨论了最近文献中使用的各种术语和概念,以指定本清单涵盖的全部或部分范围。我们认为,需要专门的术语来建立围绕这个经验领域形成的新生研究领域。作为朝这个方向迈出的一步,我们提出了“出现”的概念及其衍生物,如“紧急现象学”,“作为可能的基础候选人。
    Meditation, psychedelics, and other similar practices or induction methods that can modulate conscious experience, are becoming increasingly popular in clinical and non-clinical settings. The phenomenology associated with such practices or modalities is vast. Many similar effects and experiences are also reported to occur spontaneously. We argue that this experiential range is still not fully described or understood in the contemporary literature, and that there is an ethical mandate to research it more extensively, starting with comprehensive documentation and definition. We review 50 recent clinical or scientific publications to assess the range of phenomena, experiences, effects, after-effects, and impacts associated with a broad variety of psychoactive compounds, meditative practices, and other modalities or events. This results in a large inventory synthesizing the reports of over 30,000 individual subjects. We then critically discuss various terms and concepts that have been used in recent literature to designate all or parts of the range this inventory covers. We make the case that specialized terminologies are needed to ground the nascent research field that is forming around this experiential domain. As a step in this direction, we propose the notion of \"emergence\" and some of its derivatives, such as \"emergent phenomenology,\" as possibly foundational candidates.
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  • 文章类型: Journal Article
    背景:与普通人群和其他学生群体相比,医学基础年(FY)医生表现出更大的心理困扰。这项可行性研究调查了FY医生对正念的看法以及正念韧性和有效性训练(MRET)计划对压力的影响,幸福,和性能。
    方法:混合方法研究使用问卷调查(研究1,N=144)和MRET计划的pre-post分析设计(研究2,N=13),以及焦点小组(N=7)。
    结果:在研究1中,有28.5%的FY报告使用正念。所有五个正念方面都很重要,积极的,与心理健康相关(p<0.05)。意识(AA)和非反应性(NR)显著,与对压力的挑战反应呈正相关(p<0.05)。威胁和损失评估与AA呈负相关,NR,和非判断性(p<0.01)。感知生产力与正念方面呈正相关:描述,AA,和NR(p<0.001)。在研究2中,健康和正念方面的观察显着增加,描述,AA,NR,威胁评估下降(p<0.05)。焦点小组确定的主要主题包括重塑心态,基于价值观的行动,体现领导力和教育学。
    结论:正念之间存在关系,心理健康,和在财政年度的表现。MRETprorgamme改善了心理健康并减少了威胁评估。未来的工作可以集中资源来提高AA和NR的技能,因为这可能足以带来有意义的福祉改善,压力生活事件的生产力和认知重估。
    BACKGROUND: Medical Foundation Year (FY) doctors demonstrate greater psychological distress compared with the general population and other student groups. This feasibility study investigated FY doctors\' perceptions of mindfulness and the impact of a mindful resilience and effectiveness training (MRET) programme on stress, wellbeing, and performance.
    METHODS: Mixed-methods study utilising a questionnaire (study 1, N = 144) and a pre-post analysis design of MRET programme (study 2, N = 13), along with focus groups (N = 7).
    RESULTS: In study 1 28.5% of FY\'s reported using mindfulness. All five mindfulness facets were significantly, and positively, associated with mental wellbeing (p < 0.05). Acting with awareness (AA) and non-reactivity (NR) were significantly, positively associated with a challenge responses to stress (p < 0.05). Threat and loss appraisals were negatively associated with AA, NR, and non-judging (p < 0.01). Perceived productivity was positively associated with mindfulness facets: describing, AA, and NR (p < 0.001). In study 2, there were significant increases in wellbeing and mindfulness facets observing, describing, AA, and NR, and threat appraisals decreased (p < 0.05). The main themes identified across the focus group included Reframed Mindset, Values-Based Action, Embodied Leadership and Pedagogy.
    CONCLUSIONS: There exists a relationship between mindfulness, psychological wellbeing, and performance in FYs. The MRET prorgamme improved psychological wellbeing and reduced threat appraisals. Future work could focus resources on enhancing the skills of AA and NR, as this may be sufficient to bring about meaningful improvements in wellbeing, percieved productivity and cognitive reappraisal of stressful life events.
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  • 文章类型: Journal Article
    自我消耗描述了一种精神状态,在主要的自我控制行动后,自我控制能力暂时耗尽。这项研究的目的是调查具有集成生物反馈的简短的基于虚拟现实的正念呼吸冥想是否可以被认为是一种有效的策略,以抵消自我消耗对压力下运动技能表现的不利影响。这项研究包括两个实验,他们每个人都设计为平衡交叉试验,并基于先验样本量计算。在每个实验中,参与者以随机分配的顺序完成了两个约会,在此期间,他们被要求在以下条件前后的压力下在四个目标方块(N=16;实验2)中对足球进球进行20次篮球罚球(N=18;实验1)或20次罚球:Stroop测试引起的自我消耗,然后休息15分钟,Stroop测试引起的自我消耗,然后进行15分钟的基于虚拟现实的正念呼吸冥想和综合生物反馈。结果表明,与休息休息相比,一个简短的基于虚拟现实的正念冥想和综合生物反馈可以抵消自我消耗的有害影响(实验2),并提高压力下的运动技能表现(实验1,2)根据已确定的方法局限性得出对研究人员和从业者的启示。
    Ego-depletion describes a state of mind, where the capacity for self-control is temporarily depleted after a primary self-control action. The aim of this study was to investigate whether a brief virtual reality-based mindfulness breathing meditation with integrated biofeedback can be considered an effective strategy to counteract the detrimental effects of ego depletion on motor skill performance under pressure. The study included two experiments, each of them designed as counterbalanced cross-over trials and based on an a priori sample-size calculation. Within each experiment, participants completed two appointments in a randomly assigned order, during which they were asked to perform 20 basketball free throws (N = 18; Experiment 1) or 20 penalty kicks at a football goal in four target squares (N = 16; Experiment 2) under pressure pre and post the following conditions: Stroop-test-induced ego depletion followed by a 15 min resting break, Stroop-test-induced ego depletion followed by a 15 min virtual reality-based mindfulness breathing meditation with integrated biofeedback. Results indicate that, in comparison to a resting break, a brief virtual reality-based mindfulness meditation with integrated biofeedback can counteract the detrimental effects of ego-depletion (Experiment 2) and enhance motor skill performance under pressure (Experiment 1, 2) Implications for researchers and practitioners are derived in light of the identified methodological limitations.
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  • 文章类型: Journal Article
    介绍我们的研究旨在将冥想和基于同情心的团体治疗与饮食失调患者的护理标准进行比较,毒瘾,酒精成瘾,和抑郁症,关于接受,正念意识,自我同情,和心理困扰。方法采用设计对照研究,将冥想和以同情心为中心的团体疗法与单独的护理标准进行比较,饮食失调患者,毒瘾,酒精成瘾,和情绪障碍。进行了四份经过验证的问卷:接受和行动问卷-II(AAQ-II),评估与当前时刻完全接触的能力;正念注意意识量表(MAAS),它评估有意识地体验当下正在发生的事情的能力;自我同情量表(SCS),评估自我同情的特征,包括爱心;和症状清单-90(SCL-90),衡量心理困扰(焦虑,抑郁症,精神病行为,等。).结果共有75名受试者,其中48人代表实验组,和27代表对照组。受试者的总体平均年龄为44.8±13.2岁。实验组有统计学上的显着增加(基线与研究结束)用于AAQ-II,MAAS,和SCS分数,SCL-90评分有统计学意义的下降。在对照组中,SCL-90评分有统计学上的显著下降,但其他测量没有显著差异。在研究结束时,两组之间的比较如下:AAQ-II:0.7(-5.74至7.15),p=0.827;MAAS:4.78(-3.19至12.75),p=0.233;SCS:5.89(-3.18至14.96),p=0.199;SCL-90:-0.26(-0.62至0.1),p=0.157。结论实验组内,所有量表均有统计学显著改善。在研究结束时,两组之间的四个量表没有统计学上的显着差异。组间比较受数据可用性的限制。
    Introduction Our study aimed to compare meditation and compassion-based group therapy with the standard of care in patients with eating disorders, drug addiction, alcohol addiction, and depression, concerning acceptance, mindfulness awareness, self-compassion, and psychological distress. Methods A controlled designed study was performed, comparing meditation and compassion-focused group therapy added to the standard of care with the standard of care alone, on patients with eating disorders, drug addiction, alcohol addiction, and mood disorders. Four validated questionnaires were administered: the Acceptance and Action Questionnaire-II (AAQ-II), which assesses the ability to be fully in touch with the present moment; the Mindful Attention Awareness Scale (MAAS), which assesses the ability to experience consciously what is happening in the present moment; the Self-Compassion Scale (SCS), which assesses self-compassion characteristics, including loving-kindness; and the Symptom Checklist-90 (SCL-90), which measures psychological distress (anxiety, depression, psychotic behavior, etc.). Results There was a total of 75 subjects, out of which 48 represented the experimental group, and 27 represented the control group. The overall mean age of the subjects was 44.8 ± 13.2 years. There were statistically significant increases in the experimental group (baseline vs. end of study) for the AAQ-II, MAAS, and SCS scores, and a statistically significant decrease in the SCL-90 score. In the control group, there was a statistically significant decrease in the SCL-90 score, but no significant differences for other measurements. The comparisons between the two groups at the end of the study were as follows: AAQ-II: 0.7 (-5.74 to 7.15), p = 0.827; MAAS: 4.78 (-3.19 to 12.75), p = 0.233; SCS: 5.89 (-3.18 to 14.96), p = 0.199; SCL-90: -0.26 (-0.62 to 0.1), p = 0.157. Conclusion Within the experimental group, all scales improved statistically significantly. There were no statistically significant differences at the end of the study concerning the four scales between the groups. The comparison between groups was limited by data availability.
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  • 文章类型: Journal Article
    由于长时间的旅程以及他们在船上的工作性质,水手们会感到焦虑和睡眠障碍。早期的研究表明,循环冥想(CM)有利于管理焦虑和改善睡眠质量。因此,本研究旨在调查CM对水手焦虑和睡眠质量的影响。
    将50名水手分配到实验组(n=25)和对照组(n=25)。实验组接受45minCM,每周7天,共3周。对照组继续进行常规活动,并在接下来的3周内进行CM练习。在基线和3周结束时,采用汉密尔顿焦虑量表(HAM-A)和匹兹堡睡眠质量指数(PSQI)进行睡眠以及血压和脉搏率。使用重复测量方差分析(RMANOVA)分析组内和组间效应的数据。
    在3周后,两组之间的所有变量均存在显着差异。实验组显示出减少的焦虑(p<0.001)和改善的睡眠(p<0.001)以及血压和脉搏率的改善。对照组在3周后未显示任何显著变化。
    CM可以作为水手在船上期间管理焦虑和改善睡眠质量的例行公事。
    UNASSIGNED: Sailors undergo anxiety and sleep disturbances due to prolonged journeys and the nature of their work on ships. Earlier studies indicate Cyclic Meditation (CM) being beneficial for managing anxiety and improving sleep quality. Thus, the current study was designed to investigate the effect of CM on anxiety and sleep quality among sailors.
    UNASSIGNED: Fifty sailors were assigned to experimental (n = 25) and control (n = 25) groups. The experimental group received 45 min of CM, 7 days a week for 3 weeks. Control group continued with their routine activities and were offered CM practice the following 3 weeks. Hamilton Anxiety Scale for anxiety (HAM-A) and the Pittsburg Sleep Quality Index (PSQI) for sleep along with blood pressure and pulse rate were taken at baseline and by the end of 3 weeks. Data were analyzed using Repeated Measures Analysis of Variance (RM ANOVA) for within and between group effects.
    UNASSIGNED: Significant differences were found between the groups following 3 weeks for all the variables. Experimental group demonstrated reduced anxiety (p < 0.001) and improved sleep (p < 0.001) along with improvements in blood pressure and pulse rate. The control group did not show any significant changes following 3 weeks.
    UNASSIGNED: CM could be incorporated as a routine for sailors to manage their anxiety and improve sleep quality during the period on board ships.
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  • 文章类型: Systematic Review
    背景:围手术期的有效疼痛和焦虑管理对于接受手术和其他侵入性手术的患者仍然是一个挑战。目前的护理标准包括处方镇痛药来治疗这些疾病;然而,最近有兴趣应用限制这些药物使用的多模式策略.一种这样的方式是冥想,这已被证明是有效的缓解各种身体和心理症状在其他环境中。本系统综述旨在评估当前的冥想实践如何影响围手术期疼痛和焦虑。
    方法:我们根据系统评价和荟萃分析指南的首选报告项目对随机对照试验进行了系统评价。使用PubMedMEDLINE进行了全面的文献检索,Embase,PsycINFO,APAPsycINFO,EBM评论,Scopus,和WebofScience的所有可用日期。我们感兴趣的主要结果是使用视觉模拟量表的患者报告的疼痛和焦虑评分,简短的疼痛清单,抑郁焦虑压力量表,状态特质焦虑量表(STAI),和医院焦虑和抑郁量表(HADS)。对于HADS和STAI量表,仅报告了焦虑和焦虑状态亚组,分别。
    结果:文献检索产生1746篇文章。共筛选了286篇全文,本系统综述纳入了16项研究.共有8项研究评估了侵入性手术后的疼痛评分;5项研究报告了疼痛评分的改善,三个报告冥想练习后没有变化。10项研究评估了侵入性手术后的焦虑结果:9项报告由于冥想练习而导致整体焦虑水平下降,而一项研究报告焦虑评分没有变化。
    结论:来自此有限文献的数据表明,对于接受各种类型侵入性手术的患者,不同的冥想练习可以有效缓解围手术期的疼痛和焦虑。需要进一步的前瞻性研究来确定围手术期的常规冥想是否有效减轻围手术期的疼痛和焦虑。
    BACKGROUND: Effective pain and anxiety management during the perioperative phase remains a challenge for patients undergoing surgeries and other invasive procedures. The current standard of care involves prescribing analgesics to treat these conditions; however, there has been recent interest in applying multimodal strategies that limit the use of these medications. One such modality is meditation, which has been shown to be effective in alleviating various physical and psychological symptoms in other settings. This systematic review aims to assess how current meditative practices affect perioperative pain and anxiety.
    METHODS: We conducted a systematic review of randomized controlled trials following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A comprehensive literature search was conducted using PubMed MEDLINE, Embase, PsycINFO, APA PsycINFO, EBM Reviews, Scopus, and Web of Science for all available dates. Our primary outcomes of interest were patient-reported pain and anxiety scores using the Visual Analog Scale, the Brief Pain Inventory, the Depression Anxiety Stress Scale, the State-Trait Anxiety Inventory (STAI), and the Hospital Anxiety and Depression Scale (HADS). For the HADS and STAI scales, only the anxiety and anxiety-state subgroups were reported, respectively.
    RESULTS: The literature search yielded 1746 articles. A total of 286 full-text articles were screened, and 16 studies were included in this systematic review. A total of eight studies assessed pain scores after invasive procedures; five reported improvements in pain scores, and three reported no change after meditative practices. Ten studies assessed anxiety outcomes after invasive procedures: nine reported a decrease in overall anxiety levels as a result of meditation practices while one study reported no change in anxiety scores.
    CONCLUSIONS: Data from this limited literature suggests that different meditation practices could be effective in alleviating pain and anxiety within the perioperative phase for patients undergoing various types of invasive procedures. Future prospective studies are needed to determine whether routine meditation in the perioperative setting is effective in mitigating perioperative pain and anxiety.
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  • 文章类型: Journal Article
    非正式实践(即,将简短的冥想练习自发地纳入日常活动中)对于提高基于冥想的干预(MedBI)的功效和可及性可能很重要。然而,参与非正式实践的促进者和障碍在很大程度上是未知的。本研究旨在调查与非正式实践实施相关的因素。
    参与者来自一项随机试验,该试验在为期4周的智能手机提供的冥想训练中测试了每天5分钟和15分钟的冥想练习的效果。干预后,对17名参与者(平均年龄:37.12岁;82.35%的女性;52.94%的非拉丁裔白人)进行了非正式实践的定性访谈。鉴于有关此主题的先验知识有限,归纳内容分析被用来描述参与者在实施非正式实践方面的经历。
    数据中出现了四个总体类别,即(A)报告的非正式做法的好处,(b)整合非正式做法,(c)对非正式实践的感知障碍,(d)建议非正式做法的促进者。
    这项研究强调了解决障碍和促进者的重要性(例如,提供个性化的应用程序功能,提醒,社会支持,和重复干预内容),以鼓励个人非正式实践。调查结果为增加非正式实践参与的方法提供了建议,可能,反过来,提高MedBI的可及性和有效性。
    通过clinicaltrials.gov(NCT05229406)和OpenScienceFramework(https://osf.io/fszvj/?view_only=039b14ccbf8848bd99808c983070b635)预先注册了定性访谈参与者。这里报告的定性分析没有预先登记。
    UNASSIGNED: Informal practice (i.e., brief meditation practices incorporated spontaneously into daily activities) may be important for increasing the efficacy and accessibility of meditation-based interventions (MedBIs). However, the facilitators and barriers to engaging in informal practice are largely unknown. The current study aimed to investigate factors associated with the implementation of informal practice.
    UNASSIGNED: Participants were drawn from a randomized trial testing the effects of 5- versus 15-min daily meditation practice in a 4-week smartphone-delivered meditation training. Qualitative interviews on informal practice were conducted with 17 participants (mean age: 37.12 years; 82.35% female; 52.94% non-Latinx White) following the intervention. Given that prior knowledge on this topic is limited, inductive content analysis was utilized to characterize participants\' experiences in relation to implementing informal practice.
    UNASSIGNED: Four overarching categories emerged from the data, namely (a) reported benefits of informal practice, (b) integration of informal practice, (c) perceived barriers to informal practice, and (d) recommended facilitators of informal practice.
    UNASSIGNED: This study underscores the importance of addressing barriers and facilitators (e.g., providing personalized app features, reminders, social support, and repeating intervention content) to encourage individuals\' informal practice. Findings provide suggestions for methods to increase engagement in informal practice, which may, in turn, increase the accessibility and effectiveness of MedBIs.
    UNASSIGNED: The larger trial from which the qualitative interview participants were drawn was preregistered through clinicaltrials.gov (NCT05229406) and the Open Science Framework (https://osf.io/fszvj/?view_only=039b14ccbf8848bd99808c983070b635). The qualitative analyses reported here were not preregistered.
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  • 文章类型: Journal Article
    教学沉思神经科学正在成为一种方法,以增加我们领域对更广泛的本科人口的影响和相关性,同时也鼓励沉思的有益实践。有关该主题的面对面课程已被证明可以改善学术学习以及对科学和冥想的态度。这里我们展示了短期,沉思神经科学中的异步在线课程具有可比的好处。学生完成了冥想练习清单的决定因素(DMPI;威廉姆斯等人。,2011)和正念注意力意识量表(MAAS;Brown和Ryan,2003)在课程的开始和结束时。他们的分数显示冥想障碍减少,课程结束后正念提高,预测一系列积极行为和福祉结果的变化。学生还认为该课程在提高神经科学理解和能力方面非常有效。对照组(来自在线普通心理学课程)显示正念没有增加,冥想障碍的减少明显较弱。鉴于在线教学的快速增长以及它可以为非传统学生提供的更好访问,在线课程在学术和社会情感学习方面的成功是有希望的。因此,班级格式及其与健康相关的主题可能是一个有价值的工具,可以达到更多样化的学生群体,同时促进与个人和社会效益相关的实践。
    Teaching contemplative neuroscience is emerging as a way to increase the reach and relevance of our field to a wider undergraduate population while also encouraging the beneficial practice of contemplation. In-person classes on the topic have been shown to improve both academic learning and attitudes towards science and meditation. Here we show that a short-term, asynchronous online course in contemplative neuroscience had comparable benefits. Students completed the Determinants of Meditation Practice Inventory (DMPI; Williams et al., 2011) and the Mindful Attention Awareness Scale (MAAS; Brown and Ryan, 2003) at the start and end of the course. Their scores showed reduced barriers to meditation and improved mindfulness after the course, changes predictive of a range of positive behavioral and well-being outcomes. Students also rated the course as highly effective in advancing neuroscience understanding and competency. A comparison group (from an online general psychology class) showed no increase in mindfulness and a significantly weaker reduction in meditation barriers. This success of an online class in both academic and social-emotional learning is promising given the rapid growth of online instruction and the improved access it can provide to non-traditional students. The class format together with its health-relevant topic could thus be a valuable tool for reaching a more diverse student body while at the same time promoting practices linked to both personal and societal benefits.
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  • 文章类型: Journal Article
    背景:基于正念的计划(MBP)已显示出对心理健康的有益影响。有新的证据表明,MBP也可能与清醒意识的主观体验中的明显偏差有关。我们旨在探讨MBPs是否在不同类型的此类状态中具有因果作用。
    方法:我们进行了一项实用的随机对照试验(ACTRN12615001160527)。剑桥大学没有严重精神疾病的学生被随机接受为期8周的MBP和心理健康支持(SAU)。或者单独去SAU。我们改编了意识状态改变量表(OAV,0-100点范围)以评估日常生活中的自发经历,并在为期一年的随访问卷结束时将其作为事后次要结果。两部分模型分析比较了试验组,以及一年中正式(冥想)和非正式(日常活动)正念练习的剂量反应效应。进行了校正多重比较的敏感性分析。
    结果:我们随机分配了670名参与者;205(33%)完成了OAV。与SAU相比,MBP参与者更频繁和更密集地经历团结(两部分边际效应(ME)=6.26OAV量表点,95%置信区间(CI)=2.24,10.27,p=0.006,Cohen\sd=0.33)和反施舍更频繁(ME=4.84,95%CI=0.86,8.83,p=0.019,Cohen\sd=0.26)。正式实践预言了精神,幸福和团结的经历,洞察力,具体化,改变了含义。非正式实践预示着团结和幸福的经历。在对多重比较进行校正后,试验臂比较和非正式练习效果失去了意义,但正式实践剂量反应效应仍然显著。
    结论:结果提供了正念练习与特定意识状态改变之间因果关系的新建议。为了优化他们的影响,从业者和教师需要适当地预测和处理它们。未来的研究需要确认发现并评估机制和临床意义。
    BACKGROUND: Mindfulness-based programmes (MBPs) have shown beneficial effects on mental health. There is emerging evidence that MBPs may also be associated with marked deviations in the subjective experience of waking consciousness. We aimed to explore whether MBPs can have a causal role in different types of such states.
    METHODS: We conducted a pragmatic randomised controlled trial (ACTRN12615001160527). University of Cambridge students without severe mental illness were randomised to an 8-week MBP plus mental health support as usual (SAU), or to SAU alone. We adapted the Altered States of Consciousness Rating Scale (OAV, 0-100-point range) to assess spontaneous experiences in daily life, and included it as a post-hoc secondary outcome at the end of the one-year follow-up questionnaire. Two-part model analyses compared trial arms, and estimated dose-response effects of formal (meditation) and informal (daily activities) mindfulness practice during the year. Sensitivity analyses correcting for multiple comparisons were conducted.
    RESULTS: We randomised 670 participants; 205 (33%) completed the OAV. In comparison with SAU, MBP participants experienced unity more frequently and intensively (two-part marginal effect (ME) = 6.26 OAV scale points, 95% confidence interval (CI) = 2.24, 10.27, p = 0.006, Cohen\'s d = 0.33) and disembodiment more frequently (ME = 4.84, 95% CI = 0.86, 8.83, p = 0.019, Cohen\'s d = 0.26). Formal practice predicted spiritual, blissful and unity experiences, insightfulness, disembodiment, and changed meanings. Informal practice predicted unity and blissful experiences. Trial arm comparisons and informal practice effects lost significance after corrections for multiple comparisons, but formal practice dose-response effects remained significant.
    CONCLUSIONS: Results provide a novel suggestion of causal links between mindfulness practice and specific altered states of consciousness. To optimise their impact, practitioners and teachers need to anticipate and handle them appropriately. Future studies need to confirm findings and assess mechanisms and clinical implications.
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