■确定按性别和国家划分的臭氧相关慢性阻塞性肺疾病(COPD)负担的长期时空趋势,并探索潜在的驱动因素。
■我们从2019年全球疾病负担中检索了与臭氧相关的COPD死亡和残疾调整生命年(DALY)的数据。我们使用年龄标准化率(ASR)的自然对数与日历年的线性回归来检查ASR的趋势,并使用面板回归来确定与趋势相关的国家/地区因素。
■在1990年至2019年期间,全球由臭氧引起的COPD死亡人数在男性中从117,114人增加到208,342人,在女性中从90,265人增加到156,880人。尽管臭氧相关COPD死亡和DALY的ASR在全球范围内有所下降,他们在中低社会人口指数(SDI)地区有所增加,女性的崛起速度更快。平均最高温度升高与较高的臭氧可归因于COPD的负荷有关,而更多的绿色空间与更低的负担相关。
■在中低SDI地区需要更多的努力,尤其是对女性来说,以减少臭氧可归因于COPD的国家间不平等。全球变暖可能会加剧这种负担。扩大绿色空间可以减轻负担。
UNASSIGNED: To identify the long-term spatiotemporal trend of ozone-related chronic obstructive pulmonary disease (COPD) burden by sex and country and to explore potential drivers.
UNASSIGNED: We retrieved data of ozone-related COPD death and disability adjusted life year (DALY) from the Global Burden of Disease 2019. We used a linear regression of natural logarithms of age-standardized rates (ASRs) with calendar year to examine the trends in ASRs and a panel regression to identify country-level factors associated with the trends.
UNASSIGNED: Global ozone-attributable COPD deaths increased from 117,114 to 208,342 among men and from 90,265 to 156,880 among women between 1990 and 2019. Although ASRs of ozone-related COPD death and DALY declined globally, they increased in low and low-middle Socio-demographic Index (SDI) regions, with faster rise in women. Elevated average maximum temperature was associated with higher ozone-attributable COPD burden, while more green space was associated with lower burden.
UNASSIGNED: More efforts are needed in low and low-middle SDI regions, particularly for women, to diminish inter-country inequality in ozone-attributable COPD. Global warming may exacerbate the burden. Expanding green space may mitigate the burden.