三叉神经痛(TN)包括剧烈的阵发性疼痛,持续几秒钟到几分钟,第五脑神经的分布。TN不会危及生命,但是由于高强度的痛苦,生活变得悲惨。本研究旨在评估不同治疗方法的总体成功率。考虑到疼痛的缓解,复发率,和潜在的副作用。材料与方法在过去10年中,共治疗了203例TN患者,也就是说,包括2013年至2022年。中期治疗103例,射频消融17例,神经切除术9例,肿瘤切除术6例,微血管减压术(MVD)68例。采用稳态采集进行快速成像的磁共振成像是确定疾病病因的基本研究。结果我们机构经验的初步结果表明,多学科方法,结合医疗,外科,和非侵入性治疗,在管理TN方面取得了最有利的结果。使用这些选定的疗法,大多数患者获得了显着的疼痛减轻和改善生活质量。然而,某些亚组患者表现出更高的治疗抵抗倾向,需要进一步调查个性化治疗策略。结论我们的研究得出的结论是,TN患者没有明确的治疗方式(医疗或手术)。由于TN的病因多种多样,TN的管理也各不相同,也就是说,多学科方法。每种类型的治疗都有优点和缺点,但是当TN的原因是血管压迫和患者的一般状况允许手术时,在这种情况下,MVD应优先于消融程序。
Object Trigeminal neuralgia (TN) consists of excruciating paroxysmal pain, which lasts for seconds to minutes, in the distribution of fifth cranial nerve. TN is not life-threatening, but life became miserable because of high intensity of pain. This study aimed to assess the overall success rates of different treatments, considering pain relief, recurrence rates, and potential side effects. Material and Methods A total of 203 patients of TN treated in the period of last 10 years, that is, 2013 to 2022, were included. Medial management was in 103, radiofrequency ablation in 17, neurectomy in 9, tumor excision in 6, and microvascular decompression (MVD) was done in 68 patients. Magnetic resonance imaging brain with fast imaging employing steady-state acquisition was the basic investigation to decide the etiology of disease. Results Preliminary findings from our institutional experience indicate that a multidisciplinary approach, combining medical, surgical, and noninvasive treatments, yielded the most favorable results in managing TN. The majority of patients achieved significant pain reduction and improved quality of life with these selected therapies. However, certain subgroups of patients exhibited a higher propensity for treatment resistance, necessitating further investigation into personalized treatment strategies. Conclusion Our study concludes that there is no definitive treatment modality (either medical or surgical) available for patients with TN. As the etiology of TN is varied, management of TN also varied, that is, multidisciplinary approach. Every type of treatment has pros and cons but when the cause of TN is vascular compression and patient\'s general condition permits for surgery, in such cases MVD should be preferred over the ablative procedures.