PDF(Pubmed)
Abstract：
Liver cirrhosis arises from liver fibrosis and necroinflammation caused by various mechanisms of hepatic injury. It is a prevalent condition in clinical practice characterized by hepatocellular dysfunction, portal hypertension, and associated complications. Despite its common occurrence, the etiology and pathogenesis of liver cirrhosis remain incompletely understood, posing a significant health threat. Effective prevention of its onset and progression is paramount in medical research. Symptoms often include discomfort in the liver area, while complications such as sarcopenia, hepatic encephalopathy, ascites, upper gastrointestinal bleeding, and infection can arise. While the efficacy of Western medicine in treating liver cirrhosis is uncertain, Chinese medicine offers distinct advantages. This review explores advancements in liver cirrhosis treatment encompassing non-pharmacological and pharmacological modalities. Chinese medicine interventions, including Chinese medicine decoctions, Chinese patent medicines, and acupuncture, exhibit notable efficacy in cirrhosis reversal and offer improved prognoses. Nowadays, the combination of Chinese and Western medicine in the treatment of liver cirrhosis also has considerable advantages, which is worthy of further research and clinical promotion. Standardized treatment protocols based on these findings hold significant clinical implications.
摘要：
肝硬化起因于由各种肝损伤机制引起的肝纤维化和坏死性炎症。它是临床实践中常见的以肝细胞功能障碍为特征的疾病，门静脉高压症,和相关的并发症。尽管它很常见，肝硬化的病因和发病机制尚不完全清楚，对健康构成重大威胁。有效预防其发作和进展在医学研究中至关重要。症状通常包括肝脏区域的不适，而肌肉减少症等并发症，肝性脑病,腹水,上消化道出血,和感染可能出现。虽然西医治疗肝硬化的疗效尚不明确,中药具有明显的优势。这篇综述探讨了包括非药理学和药理学方式在内的肝硬化治疗的进展。中医干预,包括中药汤剂,中成药,和针灸，在肝硬化逆转中表现出显着的疗效，并提供改善的预后。如今,中西医结合治疗肝硬化也有相当的优势,值得进一步研究和临床推广。基于这些发现的标准化治疗方案具有重要的临床意义。
