背景:我们的研究旨在比较COVID-19大流行期与非大流行期术后发热的患病率。
方法:对2017年1月1日至2019年3月1日在南京市儿童医院(2019组)接受微创修复(也称为NUSS手术)的漏斗胸(PE)患者进行回顾性分析,2020年1月1日至2021年3月1日(2021年集团)。总共284名患者的数据,由200名(70.4%)男性和84名(29.6%)女性组成,平均年龄为9.73±3.41(范围,4至17)年,被收集。术后发热(定义为术后72小时内额头温度为37.5℃或以上),以及手术时间,术后机械呼吸机和导尿管使用的持续时间,对2019组(n=144)和2021组(n=140)的入院患者的住院时间和住院时间进行评估.术后白细胞(WBC),C反应蛋白(CRP)水平,和术后并发症的患病率(即,气胸,肺不张,肺炎,伤口感染,和开裂)也被确定。
结果:我们的结果显示,与2021组相比,2019组收治的患者在手术后24至72小时内术后发热的发生率在统计学上显着下降(p<0.001),以及峰值体温在72小时内降低(p<0.05)。同时,在年龄和体重指数(BMI)方面没有观察到显着差异,操作时间,术后机械呼吸机和导尿管使用时间比较(p>0.05)。2021组的平均住院时间明显短于2019组(12.49±2.57vs.11.85±2.19天,p<0.05)。此外,两组术后24h白细胞计数差异有统计学意义(p<0.05),CRP水平及术后并发症发生率均无差异(p>0.05)。
结论:2021组接受NUSS手术的PE患者术后72小时内发热发生率和住院时间均下降。我们建议,上述现象可能与医生增加使用个人防护设备(例如外科口罩和过滤面罩呼吸器(FFR))有关,护士,和病人自己。
BACKGROUND: Our study aimed to compare the prevalence of postoperative fever during the COVID-19 pandemic period with that of the preceding non-pandemic period.
METHODS: A retrospective analysis was conducted on patients with pectus excavatum (PE) undergoing minimally invasive repair (also called NUSS procedure) at Nanjing Children\'s Hospital from January 1, 2017 to March 1, 2019 (Group 2019), and from January 1, 2020 to March 1, 2021 (Group 2021). Data from a total of 284 patients, consisting of 200 (70.4%) males and 84 (29.6%) females with an average age of 9.73 ± 3.41 (range, 4 to 17) years, were collected. The presence of post-operative fever (defined as a forehead temperature of 37.5℃ or above within 72 h post-surgery), as well as the time of operation, duration of postoperative mechanical ventilator and urinary catheter use, and length of hospitalization were all assessed in admitted patients from Group 2019 (n = 144) and Group 2021 (n = 140). Postoperative white blood cell (WBC), C-reactive protein (CRP) levels, and prevalence of postoperative complications (i.e., pneumothorax, pulmonary atelectasis, pneumonia, wound infection, and dehiscence) were also determined.
RESULTS: Our results showed a statistically significant decrease in the incidence of postoperative fever within 24 to 72 h of surgery in patients admitted from Group 2019 as compared to Group 2021 (p < 0.001), as well as a decrease in peak body temperature within 72 h (p < 0.05). Meanwhile, no significant differences were observed in age and body mass index (BMI), time of operation, or duration of postoperative mechanical ventilator and urinary catheter use between the two groups (p > 0.05). The average hospitalization length of Group 2021 was significantly shorter than Group 2019 (12.49 ± 2.57 vs. 11.85 ± 2.19 days, p < 0.05). Furthermore, while the WBC count between the two groups 24 h after surgery showed a statistical difference (p < 0.05), no differences in CRP levels or the incidence of postoperative complications were observed (p > 0.05).
CONCLUSIONS: The prevalence of postoperative fever within 72 h of surgery and the length of hospital stay for patients with PE undergoing NUSS surgery were both decreased in Group 2021. We propose that the above phenomenon may be related to increased used of personal protection equipment (such as surgical masks and filtering facepiece respirators (FFRs)) by physicians, nurses, and the patients themselves.