目的:本研究旨在通过Missoula-Vitas生活质量指数-15(MVQOLI-15)评估维持性血液透析的终末期肾病(ESRD)患者的生活质量(QoL),以确定影响其健康的因素。
方法:在肾内科透析室进行了一项横断面研究,尼什塔尔医院木尔坦。超过六个月,140名符合条件的患者采用非概率连续抽样。使用MVQOLI-15问卷评估症状,评估年龄在18-80岁的维持性血液透析至少六个月的参与者,函数,人际关系,幸福,和QoL的超越维度。使用IBMSPSSStatisticsforWindows分析数据,版本26(2019年发布;IBMCorp.,Armonk,纽约)。推断性统计检验,包括比较两组的t检验和比较多组的方差分析(ANOVA),用于确定不同人口统计学和临床类别之间QoL评分差异的显著性。P值小于0.05被认为具有统计学意义。
结果:该研究分析了140名血液透析患者,平均年龄52.41±16.31岁,平均血液透析时间4.55±2.46年。大多数参与者年龄在61-80岁(35.7%),受过中等教育(44.3%),已婚(67.1%)。QoL分数,使用MVQOLI测量,显示症状的平均值为4.51±10.71,功能为5.77±8.04,人际关系为7.49±13.67,幸福感为-13.60±7.11,超越为8.24±13.12,总分为16.24±2.75。重要的发现包括:女性的症状评分较高(p=0.001),幸福感评分较低(p=0.000);年轻患者(<30岁)的功能评分较高(p=0.054);每周接受三次血液透析的患者的功能评分较高(p=0.006);每天服用1至3粒药丸的患者的超越评分较高(p=0.000);未婚患者的症状评分较高(p=0.064)在总分中,每周接受一次血液透析的患者的评分明显较好(p=0.011).
结论:这项研究强调了血液透析患者的不同QoL经历,超越得分最高和幸福,最低的。人口因素,如年龄,性别,教育水平显著影响QoL维度。了解这些发现可以指导个性化干预措施,以改善血液透析患者的幸福感。
OBJECTIVE: This study aimed to evaluate the quality of life (QoL) in end-stage kidney disease (ESRD) patients on maintenance hemodialysis through the Missoula-Vitas Quality of Life Index-15 (MVQOLI-15) to identify factors affecting their well-being.
METHODS: A cross-sectional study was conducted at the Dialysis Unit of the Nephrology Department, Nishtar Hospital Multan. Over six months, 140 eligible patients were enrolled using non-probability consecutive sampling. Participants aged 18-80 years on maintenance hemodialysis for at least six months were evaluated using the MVQOLI-15 questionnaire assessing symptoms, function, interpersonal, well-being, and transcendence dimensions of QoL. Data were analyzed using the IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York). Inferential statistical tests, including the t-test for comparing two groups and analysis of variance (ANOVA) for comparing multiple groups, were utilized to determine the significance of differences in QoL scores among different demographic and clinical categories. P-values less than 0.05 were considered statistically significant.
RESULTS: The study analyzed 140 hemodialysis patients, with a mean age of 52.41 ± 16.31 years and an average hemodialysis duration of 4.55 ± 2.46 years. Most participants were aged 61-80 years (35.7%), had secondary education (44.3%), and were married (67.1%). QoL scores, measured using the MVQOLI, indicated mean values for symptoms at 4.51 ± 10.71, function at 5.77 ± 8.04, interpersonal at 7.49 ± 13.67, well-being at -13.60 ± 7.11, transcendence at 8.24 ± 13.12, and a total score of 16.24 ± 2.75. Significant findings include the following: females had higher symptom scores (p=0.001) and lower well-being scores (p=0.000); younger patients (<30 years) had higher function scores (p=0.054); patients on hemodialysis three times per week had higher function scores (p=0.006); patients taking 1 to 3 pills per day had higher transcendence scores (p=0.000); unmarried patients had higher symptoms scores (p=0.064) and lower well-being scores (p=0.004); and illiterate patients had higher symptoms (p=0.005) and transcendence scores (p=0.034). In total score, patients on hemodialysis once per week reported significantly better scores (p=0.011).
CONCLUSIONS: This study highlights varied QoL experiences among hemodialysis patients, with transcendence scoring the highest and well-being, the lowest. Demographic factors such as age, gender, and education level significantly impact the QoL dimensions. Understanding these findings can guide personalized interventions to improve the well-being of hemodialysis patients.