PDF(Pubmed)
Abstract：
UNASSIGNED: Quality-of-life (QOL) is important for cancer patients with poor prognosis. However, conducting a QOL survey with patients is difficult. Therefore, we conducted a QOL survey with physicians. Specifically, this study aimed to clarify how physicians assess QOL in patients with pancreatic cancer by conducting a survey and comparing the results between physicians and the general public.
UNASSIGNED: A survey was conducted by interviewing physicians administering chemotherapy to patients for recurrent/metastatic pancreatic cancer. This method is similar to that of the QOL survey conducted among the general public. Responses were evaluated using the composite time trade-off (cTTO) and the visual analog scale (VAS) for 11 pancreatic cancer status scenarios (survey scenarios). These scenarios consisted of patients\' health states as well as the types and grades of adverse events (AEs). Health status was classified into two categories: Stable disease (SD) and Progressive disease (PD). In addition, we conducted a survey using the EuroQol 5 Dimensions 5-Level (EQ-5D-5l) as reference values.
UNASSIGNED: Twenty physicians responded to the survey. SD had the highest mean QOL value for both assessment methods (Physicians: 0.78, General public: 0.63), whereas PD had the lowest mean QOL value (Physicians: 0.15, General public: -0.12). The physicians assigned higher QOL values on both the VAS and cTTO than the general public did in all survey scenarios.
UNASSIGNED: The QOL values obtained from physicians were consistent with the degree of status in any assessment scenarios. Based on the differences in the QOL survey results between physicians and the general public, physicians tended to assign higher QOL values than the general public in cTTO and VAS assessments.
UNASSIGNED: A survey was conducted by interviewing physicians administering chemotherapy to patients for recurrent/metastatic pancreatic cancer. This method is similar to that of the QOL survey conducted among the general public. Responses were evaluated using the composite time trade-off (cTTO) and the visual analog scale (VAS) for 11 pancreatic cancer status scenarios (survey scenarios). These scenarios consisted of patients\' health states as well as the types and grades of adverse events (AEs). Health status was classified into two categories: Stable disease (SD) and Progressive disease (PD). In addition, we conducted a survey using the EuroQol 5 Dimensions 5-Level (EQ-5D-5l) as reference values.
UNASSIGNED: Twenty physicians responded to the survey. SD had the highest mean QOL value for both assessment methods (Physicians: 0.78, General public: 0.63), whereas PD had the lowest mean QOL value (Physicians: 0.15, General public: -0.12). The physicians assigned higher QOL values on both the VAS and cTTO than the general public did in all survey scenarios.
UNASSIGNED: The QOL values obtained from physicians were consistent with the degree of status in any assessment scenarios. Based on the differences in the QOL survey results between physicians and the general public, physicians tended to assign higher QOL values than the general public in cTTO and VAS assessments.
摘要：
■生活质量（QOL）对于预后不良的癌症患者很重要。然而,对患者进行QOL调查很困难。因此,我们与医生进行了QOL调查。具体来说,本研究旨在通过开展一项调查并比较医师与公众的结果,阐明医师如何评估胰腺癌患者的生活质量.
■通过采访医生对复发/转移性胰腺癌患者进行化疗进行调查。这种方法类似于在公众中进行的QOL调查。使用11种胰腺癌状态情景（调查情景）的复合时间权衡（cTTO）和视觉模拟量表（VAS）评估反应。这些情景包括患者的健康状况以及不良事件（AE）的类型和等级。健康状况分为两类：稳定疾病（SD）和进行性疾病（PD）。此外,我们使用EuroQol5Dimensions5-Level（EQ-5D-5l）作为参考值进行了调查。
■20位医生回答了这项调查。两种评估方法的SD平均QOL值最高（医师：0.78，公众：0.63），而PD的平均生活质量值最低(医师:0.15,公众:-0.12)。在所有调查方案中，医生在VAS和cTTO上分配的QOL值均高于普通公众。
■从医生那里获得的QOL值与任何评估方案中的状态程度一致。根据医生和普通公众的QOL调查结果的差异，在cTTO和VAS评估中,医生倾向于赋予比一般公众更高的QOL值.
■通过采访医生对复发/转移性胰腺癌患者进行化疗进行调查。这种方法类似于在公众中进行的QOL调查。使用11种胰腺癌状态情景（调查情景）的复合时间权衡（cTTO）和视觉模拟量表（VAS）评估反应。这些情景包括患者的健康状况以及不良事件（AE）的类型和等级。健康状况分为两类：稳定疾病（SD）和进行性疾病（PD）。此外,我们使用EuroQol5Dimensions5-Level（EQ-5D-5l）作为参考值进行了调查。
■20位医生回答了这项调查。两种评估方法的SD平均QOL值最高（医师：0.78，公众：0.63），而PD的平均生活质量值最低(医师:0.15,公众:-0.12)。在所有调查方案中，医生在VAS和cTTO上分配的QOL值均高于普通公众。
■从医生那里获得的QOL值与任何评估方案中的状态程度一致。根据医生和普通公众的QOL调查结果的差异，在cTTO和VAS评估中,医生倾向于赋予比一般公众更高的QOL值.
