■弗雷综合征,露西·弗雷在1923年描述,是一种以出汗为特征的独特状况,冲洗,发红是对咀嚼的直接反应。这种现象是由源自耳颞神经的节后副交感神经元的异常再生以及随后由咀嚼刺激引起的乙酰胆碱分泌引起的。虽然罕见,这种综合征可能有多种潜在原因,经常被观察到,发生在高达65%的病例后腮腺外侧切除术。此外,它在颈部解剖后不太常见,整容程序,或与糖尿病有关。
■本文概述了针对弗雷综合征的全面诊断算法,其中包括利用少量淀粉-碘测试。该测试是诊断综合征的关键组成部分,并进行了详细讨论,提供对其程序和解释的见解。此外,治疗已确定的弗雷综合征的黄金标准,肉毒杆菌毒素A,被彻底描述,包括它的作用机制,administration,和潜在的副作用。
■最后,这篇文章强调需要进一步研究,以提高我们对弗雷综合征的理解,为患者提供更好的诊断方法和更量身定制的治疗方案。
UNASSIGNED: Frey\'s syndrome, described by Lucy Frey in 1923, is a unique condition characterized by sweating, flushing, and reddening as a direct response to mastication. This phenomenon results from the aberrant regeneration of postganglionic parasympathetic neurons originating from the auriculotemporal nerve and the subsequent acetylcholine secretion induced by masticatory stimuli. Although rare, this syndrome can have multiple underlying causes and is frequently observed, occurring in up to 65% of cases following lateral parotid resections. Additionally, it can less commonly manifest after neck dissection, facelift procedures, or be associated with diabetes mellitus.
UNASSIGNED: This article outlines a comprehensive diagnostic algorithm for Frey\'s syndrome, which includes the utilization of the Minor-Starch-Iodine Test. This test is a key component in diagnosing the syndrome and is discussed in detail, providing insights into its procedure and interpretation. Additionally, the gold standard of treatment for established Frey\'s syndrome, botulinum toxin A, is thoroughly described, including its mechanism of action, administration, and potential side effects.
UNASSIGNED: Finally, the article underscores the need for further research to enhance our understanding of Frey\'s syndrome, leading to better diagnostic methods and more tailored treatment options for patients.