背景:糖尿病性黄斑水肿(DME)显著损害糖尿病患者的视力,患者对当前治疗如抗血管内皮生长因子(VEGF)治疗的反应各不相同,这突显了继续研究更有效策略的必要性。本研究旨在评估全球研究趋势,并确定DME的新兴前沿,以指导未来的研究和临床管理。
方法:对从WebofScienceCoreCollection(WoSCC)开始至2023年9月4日之间与糖尿病性黄斑水肿相关的出版物进行了定性和定量分析。MicrosoftExcel,CiteSpace,VOSviewer,Bibliometrix包,和Tableau用于文献计量分析和可视化。这包括检查年产量的总体分布,主要国家,regions,机构,作者,核心期刊,共同引用的参考文献,和关键词分析。
结果:总体而言,分析了5624种出版物,表明二甲醚研究呈上升趋势。美国被确定为DME研究的领先国家,最高的h指数为135和91,841次引用。FrancescoBandello以97种出版物成为最多产的作家。NeilM.Bressler的h指数最高,总引文计数最高,分别为46和9692。“视网膜-视网膜和玻璃体疾病杂志”和“眼科”杂志被强调为该领域最突出的杂志。“视网膜”以354种出版物领先,引文计数为11,872,h指数为59。同时,“眼科”以最高的总引文计数31,558和最高的h指数90脱颖而出。糖尿病性黄斑水肿的主要研究重点包括患病率和危险因素。“\”病理机制,成像模式,“\”治疗策略,“和”临床试验。“新兴的研究领域包括深度学习和人工智能,新的治疗方式,“和”生物标志物。\"
结论:我们的文献计量分析描绘了美国在DME研究中的主导作用。我们确定了当前的研究热点,包括流行病学研究,病理生理机制,成像进步,和治疗创新。新兴趋势,例如人工智能和新的治疗方法的集成,突出未来方向。这些见解强调了协作和跨学科方法在推进DME研究和临床管理方面的重要性。
BACKGROUND: Diabetic Macular Edema (DME) significantly impairs vision in diabetics, with varied patient responses to current treatments like anti-vascular endothelial growth factor (VEGF) therapy underscoring the necessity for continued research into more effective strategies. This study aims to evaluate global research trends and identify emerging frontiers in DME to guide future research and clinical management.
METHODS: A qualitative and quantitative analysis of publications related to diabetic macular edema retrieved from the Web of Science Core Collection (WoSCC) between its inception and September 4, 2023, was conducted. Microsoft Excel, CiteSpace, VOSviewer, Bibliometrix Package, and Tableau were used for the bibliometric analysis and visualization. This encompasses an examination of the overall distribution of annual output, major countries, regions, institutions, authors, core journals, co-cited references, and keyword analyses.
RESULTS: Overall, 5624 publications were analyzed, indicating an increasing trend in DME research. The United States was identified as the leading country in DME research, with the highest h-index of 135 and 91,841 citations. Francesco Bandello emerged as the most prolific author with 97 publications. Neil M. Bressler has the highest h-index and highest total citation count of 46 and 9692, respectively. The journals \"Retina - the Journal of Retinal and Vitreous Diseases\" and \"Ophthalmology\" were highlighted as the most prominent in this field. \"Retina\" leads with 354 publications, a citation count of 11,872, and an h-index of 59. Meanwhile, \"Ophthalmology\" stands out with the highest overall citation count of 31,558 and the highest h-index of 90. The primary research focal points in diabetic macular edema included \"prevalence and risk factors,\" \"pathological mechanisms,\" \"imaging modalities,\" \"treatment strategies,\" and \"clinical trials.\" Emerging research areas encompassed \"deep learning and artificial intelligence,\" \"novel treatment modalities,\" and \"biomarkers.\"
CONCLUSIONS: Our bibliometric analysis delineates the leading role of the United States in DME research. We identified current research hotspots, including epidemiological studies, pathophysiological mechanisms, imaging advancements, and treatment innovations. Emerging trends, such as the integration of artificial intelligence and novel therapeutic approaches, highlight future directions. These insights underscore the importance of collaborative and interdisciplinary approaches in advancing DME research and clinical management.