背景:关于移民人群中1型单纯疱疹病毒(HSV-1)和2型单纯疱疹病毒(HSV-2)感染的数据有限。这项研究调查了占卡塔尔人口60%的卡塔尔手工工人和体力劳动者(CMW)之间的HSV-1和HSV-2血清感染率和关联。
方法:对CMW人群进行了基于全国人群的横断面血清阳性率调查,所有的男人,2020年7月26日至9月9日。使用HerpeSelect1ELISAIgG试剂盒测试了2,612份血清的抗HSV-1IgG抗体,并使用HerpeSelect2ELISAIgG试剂盒测试了抗HSV-2IgG抗体(FocusDiagnostics,美国)。进行单变量和多变量逻辑回归分析以确定与HSV-1和HSV-2感染的关联。
结果:血清学检测确定2,171份血清为阳性,403为阴性,和38对于HSV-1抗体是模棱两可的,和300血清为阳性,2,250为负,和62对于HSV-2抗体是模棱两可的。CMW中的HSV-1和HSV-2血清感染率估计为84.2%(95%CI82.8-85.6%)和11.4%(95%CI10.1-12.6%),分别。HSV-1感染与国籍有关,教育程度,和职业。HSV-2感染与年龄有关,国籍,和教育程度。
结论:超过80%的CMW感染HSV-1,超过10%感染HSV-2。研究结果强调了性健康计划的必要性,以解决CMW人群中的性传播感染。
Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual workers (CMWs) in Qatar who constitute 60% of Qatar\'s population.
A national population-based cross-sectional seroprevalence survey was conducted on the CMW population, all men, between July 26 and September 9, 2020. 2,612 sera were tested for anti-HSV-1 IgG antibodies using HerpeSelect 1 ELISA IgG kits and for anti-HSV-2 IgG antibodies using HerpeSelect 2 ELISA IgG kits (Focus Diagnostics, USA). Univariable and multivariable logistic regression analyses were conducted to identify associations with HSV-1 and HSV-2 infections.
Serological testing identified 2,171 sera as positive, 403 as negative, and 38 as equivocal for HSV-1 antibodies, and 300 sera as positive, 2,250 as negative, and 62 as equivocal for HSV-2 antibodies. HSV-1 and HSV-2 seroprevalences among CMWs were estimated at 84.2% (95% CI 82.8-85.6%) and 11.4% (95% CI 10.1-12.6%), respectively. HSV-1 infection was associated with nationality, educational attainment, and occupation. HSV-2 infection was associated with age, nationality, and educational attainment.
Over 80% of CMWs are infected with HSV-1 and over 10% are infected with HSV-2. The findings highlight the need for sexual health programs to tackle sexually transmitted infections among the CMW population.