UNASSIGNED:将多普勒超声(DUS)门控的胎儿心脏MRI应用于临床常规,并与胎儿超声心动图进行比较,以探讨复杂先天性心脏病(CHD)的诊断性能。
未经评估:在这项前瞻性研究中(2021年5月至2022年3月),患有CHD胎儿的女性在同一天接受了胎儿超声心动图和DUS门控胎儿心脏MRI检查.MRI,在轴向和可选的矢状和/或冠状方向上获取平衡的稳态自由进动电影图像。总体图像质量以四点李克特量表进行评估(从1=非诊断性到4=良好的图像质量)。通过使用两种模式独立评估20个胎儿心血管特征中异常的存在。参考标准为产后检查结果。通过使用随机效应模型确定敏感性和特异性的差异。
未经评估:该研究包括23名参与者(平均年龄,32岁±5[SD];平均胎龄,36周±1)。所有参与者均完成胎儿心脏MRI检查。DUS门控电影图像的整体图像质量中位数为3(IQR,2.5-4).23名参与者中有21名(91%)通过使用胎儿心脏MRI正确评估基础CHD.在一个案例中,仅通过MRI(内位和先天性矫正的大动脉转位)做出正确诊断。MRI和超声心动图检测异常心血管特征的敏感性(91.8%[95%CI:85.7,95.1]vs93.6%[95%CI:88.8,96.2];P=.53)和特异性(99.9%[95%CI:99.2,100]vs99.9%[95%CI:99.5,100];P>.99)分别。
UNASSIGNED:使用DUS门控的胎儿电影心脏MRI的性能与使用胎儿超声心动图诊断复杂胎儿冠心病的性能相当。关键词:儿科,MR-胎儿(胎儿MRI),心脏,心,先天性,胎儿成像,心脏MRI,产前,先天性心脏病临床试验登记号。NCT05066399补充材料可用于本文。©RSNA,2023另见本期Biko和Fogel的评论。
UNASSIGNED: To apply Doppler US (DUS)-gated fetal cardiac cine MRI in clinical routine and investigate diagnostic performance in complex congenital heart disease (CHD) compared with that of fetal echocardiography.
UNASSIGNED: In this prospective study (May 2021 to March 2022), women with fetuses with CHD underwent fetal echocardiography and DUS-gated fetal cardiac MRI on the same day. For MRI, balanced steady-state free precession cine images were acquired in the axial and optional sagittal and/or coronal orientations. Overall image quality was assessed on a four-point Likert scale (from 1 = nondiagnostic to 4 = good image quality). The presence of abnormalities in 20 fetal cardiovascular features was independently assessed by using both modalities. The reference standard was postnatal examination results. Differences in sensitivities and specificities were determined by using a random-effects model.
UNASSIGNED: The study included 23 participants (mean age, 32 years ± 5 [SD]; mean gestational age, 36 weeks ± 1). Fetal cardiac MRI was completed in all participants. The median overall image quality of DUS-gated cine images was 3 (IQR, 2.5-4). In 21 of 23 participants (91%), underlying CHD was correctly assessed by using fetal cardiac MRI. In one case, the correct diagnosis was made by using MRI only (situs inversus and congenitally corrected transposition of the great arteries). Sensitivities (91.8% [95% CI: 85.7, 95.1] vs 93.6% [95% CI: 88.8, 96.2]; P = .53) and specificities (99.9% [95% CI: 99.2, 100] vs 99.9% [95% CI: 99.5, 100]; P > .99) for the detection of abnormal cardiovascular features were comparable between MRI and echocardiography, respectively.
UNASSIGNED: Using DUS-gated fetal cine cardiac MRI resulted in performance comparable with that of using fetal echocardiography for diagnosing complex fetal CHD.Keywords: Pediatrics, MR-Fetal (Fetal MRI), Cardiac, Heart, Congenital, Fetal Imaging, Cardiac MRI, Prenatal, Congenital Heart DiseaseClinical trial registration no. NCT05066399 Supplemental material is available for this article. © RSNA, 2023See also the commentary by Biko and Fogel in this issue.