虽然人类接触金属可能在贫血的发病机理中起作用,均衡饮食的消费可能会提高人类的血液血红蛋白(Hb)水平。尽管非正式的电子废物(电子废物)回收过程最近引起了人们的注意,作为一个重要的污染源,几乎没有关于饮食之间关系的经验证据,电子垃圾回收商的金属暴露和贫血。因此,我们评估了饮食对金属暴露相关贫血的可能改善作用,以加纳电子垃圾回收者和参考人群的Hb水平衡量。这项重复测量研究使用了2017年3月至2018年10月从电子垃圾回收商(n=142)和参考人群(n=65)收集的数据。分析了储存的全血样品中的以下金属;Cd,Pb,Rb,TB,Tl,还有Eu.接下来,使用URIT-810®半自动生物化学分析仪分析Hb水平。此外,进行了48小时的饮食回忆问卷,以评估饮食摄入参数,如蛋白质,叶酸,碳水化合物,Fe,Ca,Mg,Se,Zn,和Cu。使用普通回归模型来估计金属和营养素对Hb水平的联合影响。在基线,回收者的平均Hb(12.99±3.17g/dL)低于参照组(13.02±2.37g/dL).血Pb,Cd,Rb,Eu和Tb与电子垃圾回收者的Hb水平显着下降有关。蛋白质和铁的饮食摄入与两组的Hb水平同时增加有关,并且分析仅限于回收者。尽管电子垃圾回收商大量接触各种金属,食用富含铁的饮食似乎可以改善贫血并改善Hb水平(β=0.229;95%CI:0.013,0.445;p=0.04)。因此,食用富含铁和蛋白质的食物可能会提高电子垃圾回收商的血液Hb水平,即使接触高水平的金属是这一工人群体贫血的预测因素。
While human exposure to metals may play a role in the pathogenesis of anemia, consumption of balanced diets may boost blood hemoglobin (Hb) levels in humans. Although informal electronic waste (e-waste) recycling processes have recently drawn attention as an important source of pollution, there is almost no empirical evidence on the relationship between diet, metals exposure and anemia among e-waste recyclers. Therefore, we evaluated possible ameliorating effects of diet on metal exposure related anemia, as measured by Hb levels of e-waste recyclers and a reference population in Ghana. This repeated measure study used data collected from e-waste recyclers (n=142) and a reference population (n=65) between March 2017 and October 2018. Stored whole blood samples were analyzed for the following metals; Cd, Pb, Rb, Tb, Tl, and Eu. Next, Hb levels were analysed using the URIT-810® semiautomatic biochemistry analyzer. Furthermore, a 48-hour dietary recall questionnaire was administered to assess dietary intake parameters such as protein, folate, carbohydrates, Fe, Ca, Mg, Se, Zn, and Cu. Ordinary regression models were used to estimate joint effects of metals and nutrients on Hb levels. At baseline, the mean Hb was lower among recyclers (12.99 ± 3.17 g/dL) than the reference group (13.02 ±2.37 g/dL). Blood Pb, Cd, Rb, Eu and Tb were associated with significant decreases in Hb levels of e-waste recyclers. Dietary intake of proteins and Fe was associated with concomitant increase in Hb levels of both groups as well as when analysis was restricted to recyclers. Despite the high exposure of e-waste recyclers to a myriad of metals, consumption of Fe-rich diets appears to ameliorate anemia and improved Hb levels (β=0.229; 95% CI: 0.013, 0.445; p=0.04). Therefore, the consumption of Fe and protein-rich foods may boost blood Hb levels in e-waste recyclers, even though exposure to high levels of metals is a predictor of anemia among this worker-group.