■本研究的目的是在临床上评估下颌阻生第三磨牙拔除术的皮瓣设计对其邻居远端牙周组织的影响,免疫学,和微生物学。
这项随机对照研究包括100名患者,他们被随机分配接受三角形皮瓣或改良三角形皮瓣。远端牙周袋深度,菌斑指数,探查时出血,放线菌放线杆菌的存在,牙龈卟啉单胞菌和中间普雷沃氏菌,白细胞介素-1β的水平,在基线测量邻近第二磨牙的白细胞介素-8和基质金属蛋白酶-8,术后1、4、8周。
■1周和4周后,邻近第二磨牙的远端牙周状况恶化,同时两组牙龈下微生物群和炎症因子的增加。并与改良三角皮瓣组比拟,三角皮瓣组明显增多(p<0.05)。中间介体普雷沃特拉,两组白细胞介素-1β与探查深度呈正相关。8周后,他们回到了术前水平。
■在这项研究中,两个皮瓣设计的下颌阻生第三磨牙拔除与较差的临床牙周指数相关,增加龈沟液的炎症生物标志物,和更多的牙龈下病原微生物在4周内。但是与三角形皮瓣相比,改良三角瓣对邻近第二磨牙的远端牙周健康效果更好,为临床治疗提供了一定的方向。
UNASSIGNED: The aim of this study was to assess the effect of flap design for impacted mandibular third molar extraction on the distal periodontal tissue of their neighbors clinically, immunologically, and microbiologically.
UNASSIGNED: This randomized controlled study comprised 100 patients who were allocated randomly to receive either a triangular flap or a modified triangular flap. The distal periodontal pocket depth, plaque index, bleeding on probing, the presence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia, and the level of interleukin-1β, interleukin-8 and matrix metalloproteinase-8 of adjacent second molars were measured at baseline, and 1, 4 and 8 weeks after surgery.
UNASSIGNED: After 1 and 4 weeks, distal periodontal conditions of adjacent second molars deteriorated, along with an increase in subgingival microbiota and inflammatory factors in both groups. And compared to the modified triangular flap group, the triangular flap group significantly increased (p < 0.05). Prevotella intermedia, interleukin-1β and probing depth were positively correlated in both groups. After 8 weeks, they returned to the preoperative level.
UNASSIGNED: In this study, both flap designs for impacted mandibular third molar extractions was associated with worse clinical periodontal indices, increased inflammatory biomarkers of gingival crevicular fluid, and more subgingival pathogenic microbiota within 4 weeks. But compared with the triangular flap, the modified triangular flap was better for distal periodontal health of adjacent second molars, which provides certain directions for clinical treatment.