背景:大蒜是一种著名的香料,也是中药中的草药,用于增加性欲和治疗勃起功能障碍。然而,没有太多的研究来评估马铃薯的性增强特性。这项研究的目的是评估马铃薯对海绵体平滑肌(CCSM)的壮阳和血管松弛特性,并检查对增强雄性大鼠性行为的作用。性欲,效力及其生精特性。
方法:将种子粉化,依次用己烷提取,乙酸乙酯和丁醇。向雄性Wistar大鼠施用分级剂量的马铃薯n-BuOH提取物(ATB)(50、100、200和400mg/kg),并将伟哥用作阳性对照药物。通过胃探针每天一次施用提取物/药物,持续45天,并通过在发情期将雄性大鼠暴露于雌性大鼠来分析性行为。
结果:ATB以200μg/ml的浓度松弛了海绵体平滑肌(68.9%)。从动物研究中获得的结果表明,ATB显着增加了安装频率(MF),引入频率(IF),射精频率(EF),射精潜伏期(EL)和射精后间隔(PEI)显着减少,挂载延迟(ML),和内渗延迟(IL)。此外,一个显着增加的测试的效力被观察到的显著增加的勃起,快速翻转,长翻转和完全反射。此外,ATB显着提高了精子的活力和数量,并增加了睾丸激素的浓度,卵泡刺激素(FSH),和治疗动物中的磷酸酶。
结论:因此,我们的结果表明,马铃薯可以刺激雄性大鼠的性唤起并增强性执行,因此提供了有价值的实验证据,表明马铃薯具有性增强特性。
BACKGROUND: Allium tuberosum is a well-known spice as well as a herb in traditional Chinese medicine, used for increasing libido and treating erectile dysfunction. However, not many studies have been done to evaluate the sexual enhancing properties of A. tuberosum. The aim of this study was to evaluate the
aphrodisiac and vasorelaxant properties of A. tuberosum on corpus cavernosum smooth muscle (CCSM) as well as checking the effect on enhancing male rat sexual behavior, libido, potency as well as its spermatogenic properties.
METHODS: The seeds were powdered and sequentially extracted with hexane, ethyl acetate and butanol. Male Wistar rats were administered with graded doses of the n-BuOH extracts (ATB) of A. tuberosum (50, 100, 200 and 400 mg/kg) and Viagra was used as the positive control drug. The extract/drug was administered by gastric probe once daily for 45 days and the sexual behavior was analyzed by exposing the male rats to female rats in the estrus period.
RESULTS: ATB relaxed corpus cavernosum smooth muscle (68.9%) at a concentration of 200 μg/ml. The results obtained from the animal studies indicated that ATB significantly increased mount frequency (MF), intromission frequency (IF), ejaculation frequency (EF), ejaculation latency (EL) and markedly reduced post ejaculatory interval (PEI), mount latency (ML), and intromission latency (IL). Furthermore, a remarkable increase in the test for potency was observed as witnessed by marked increase in erections, quick flips, long flips and total reflex. In addition, ATB significantly improved the sperm viability and count as well as increased the concentrations of testosterone, follicle stimulating hormone (FSH), and phosphatases in the treated animals.
CONCLUSIONS: Thus our results suggest that A. tuberosum could stimulate sexual arousal and enhance sexual execution in male rats, thus providing valuable experimental evidence that A. tuberosum possesses sexual enhancing properties.