Objective: To analyze the clinical features and surgical outcomes of petrous bone cholesteatomas (PBCs). Methods: Data from 39 PBCs patients treated in the Department of Otorhinolaryngology, Xijing Hospital from September 2011 to December 2017 were reviewed retrospectively, including 23 males, 16 femals, aged 12-71 years old, with the median age of 37. Clinical classifications, surgical methods, facial and hearing function, and intraoperative and postoperative complications were made summary analysis. Results: In this study, five patients were congenital PBCs and 34 patients were acquired PBCs. The common clinical symptoms were hearing loss (100%, 39/39), ear discharge/pus (89.7%, 35/39) and facial paralysis (46.2%, 18/39). According to Sanna\'s classification, 14 cases were supralabyrinthine, including three cases underwent transcochlear (TC) approach, six cases underwent transotic (TO) approach and five underwent translabyrinthine (TL) approach. 10 cases were infralabyrinthine, including eight cases underwent subtotal petrosectomy, one case underwent TO approach and one underwent TL approach.10 cases were massive, including seven cases underwent TC approach, three cases underwent TO approach. Five cases were infralabyrinthine-apical, including two cases underwent TC approach, two cases underwent TO approach, and one case underwent endoscope assisted infratemporal fossa type B. The degree of facial nerve (FN) dysfunction from high to low was massive (6/10), supralabyrinthine (8/14), infralabyrinthine-apical (2/5) and infralabyrinthine (2/10). 19 cases involved in facial nerve operation, three cases underwent FN decompression, four cases underwent FN rerouting, four cases underwent nerve grafting, and one case underwent facial-hypoglossal anastomosis. Preoperative FN involvement in 18 cases, and the FN function was improved in 14 cases after surgery. The improved rate of postoperative FN function was 77.8%. The bone conducted hearing retained 50.0% (14/28) postoperatively. Five cases with cerebrospinal fluid leak were managed by inserting free muscle plugs and cavity obliteration. Two cases with the cholesteatomas matrix involved the sigmoid sinus and the jugular bulb, and occlusion of the sigmoid sinus was performed. Postoperatively, two patients presented with synkinesis. The patients were followed up for 40 to 115 months, and there was no recurrence. Conclusions: There are no specific clinical manifestations for PBCs, thus, it is difficult in early diagnosis and treatment. According to Sanna\'s classification, preoperative FN and hearing function, the best surgical approach should be selected with minimal recurrences and perioperative morbidity.
目的: 探讨分析岩部胆脂瘤的病变特点、手术方式和疗效。 方法: 回顾性分析2011年9月至2017年12月空军军医大学西京医院耳鼻咽喉科收治的39例随访时间超过3年、资料完整的颞骨岩部胆脂瘤患者的临床资料,其中男性23例,女性16例,年龄12~71岁,中位年龄37岁,总结分析其病变分型、手术方式、面听神经功能以及术中、术后并发症等。 结果: 本组患者中先天性岩部胆脂瘤5例,获得性岩部胆脂瘤34例。常见临床症状分别为听力下降(100%,39/39)、耳溢液/流脓(89.7%,35/39)以及面神经麻痹(46.2%,18/39)。按Sanna分型,迷路上型岩部胆脂瘤14例,其中3例采用耳蜗径路、6例采用耳囊径路、5例采用迷路径路;迷路下型岩部胆脂瘤10例,其中8例采用岩骨次全切、1例采用耳囊径路、1例采用迷路径路;广泛型岩部胆脂瘤10例,其中7例采用耳蜗径路、3例采用耳囊径路;迷路下-岩尖型岩部胆脂瘤5例,其中2例采用耳蜗径路、2例采用耳囊径路、1例行耳内镜辅助颞下窝B型径路。面神经受累率由高到低依次为广泛型(6/10)、迷路上型(8/14)、迷路下-岩尖型(2/5)、迷路下型(2/10)。19例术中涉及面神经手术操作,3例行面神经全程减压,4例行面神经改道吻合,4例行面神经耳大神经移植,1例行面神经-舌下神经吻合,面神经移位者7例。18例患者术前面神经受累,术后14例面神经功能得以改善,术后面神经功能改善率为77.8%(14/18)。手术多采用颞侧入路,骨导听力保存率为50.0%(14/28)。术中5例发生脑脊液漏,给予肌肉填塞并封腔处理;2例因病变粘在乙状窦和颈静脉球表面较难剥离,术中予以填塞并结扎乙状窦。术后2例患者出现面肌联动。术后随访40~115个月,无复发病例。 结论: 颞骨岩部胆脂瘤临床表现缺乏特异性,早期诊断具有一定难度。应根据病变类型及面听神经功能,选择合适的手术方式,以达到在彻底清除病变的同时,保护重要神经和血管功能,降低术后并发症和复发率。.