背景:黑素细胞痣通常出现在儿童早期,移除它们是对儿童进行的常见整形手术。然而,儿童黑素细胞痣的流行病学特征和住院负担很少有详细的描述。
方法:收集2016年1月1日至2021年12月31日期间患有黑素细胞痣的儿科住院患者的病历,这些病历来自中国儿科发展数据库的福堂研究中心。然后,我们提取并统计分析相关信息,包括人口特征,临床信息,住院负担,以及每个住院患者的其他基本信息。
结果:在13,396例黑素细胞痣患者中,发现病例最多的是华东地区,大多数患者是城市地区的居民。大多数住院患者包括7-12岁的男孩,患有黑素细胞痣。臀部和下肢的病变部位在患有黑素细胞痣的儿科住院患者中最常见。在患有黑素细胞痣的儿科住院患者中,复合痣是最常见的(38.50%)组织学亚型,转变为黑色素瘤的比率为1.02%(137名住院患者)。根据接受手术的患者的年龄等因素,患者的住院负担差异很大,住院年份,病变部位,组织学亚型,和手术方法。总的来说,如果患者年龄在1岁以下,病变部位位于面部,并且需要切除联合组织扩张器可以显着增加儿童住院黑素细胞痣患者的治疗费用。
结论:鉴于在中国住院的黑素细胞痣患儿数量不断增加,住院负担相对较大,政府需要更加关注这一群体,并提供相应的经济和政策支持。
BACKGROUND: Melanocytic nevi typically appear in early childhood, and their removal is a common plastic surgery procedure performed on children. However, the epidemiological characteristics and hospitalization burden of children with melanocytic nevi have rarely been described in detail.
METHODS: Medical records of pediatric inpatients with melanocytic nevi from January 1, 2016, to December 31, 2021, were collected from the Futang Research Center of Pediatric Development database in
China. We then extracted and statistically analyzed the relevant information, including demographic characteristics, clinical information, hospitalization burden, and other basic information for each inpatient.
RESULTS: Among the 13,396 inpatients with melanocytic nevi, the highest number of cases was found in East
China, and most patients were residents of urban areas. Most hospitalized patients consisted of boys aged 7-12 years with melanocytic nevi. Lesion sites in the buttocks and lower limbs were most common among pediatric inpatients with melanocytic nevi. Compound nevi were the most common (38.50 %) histological subtype and the rate of conversion into melanoma was 1.02 % (137 inpatients) among pediatric inpatients with melanocytic nevi. The hospitalization burden for patients varied significantly based on factors such as the age of the patients undergoing surgery, year of hospitalization, site of the lesion, histological subtype, and surgical method. In general, if the patients\' age was under 1 year, lesion site was located in face, and there was a need for excision combined with tissue expander can significantly increase the treatment fees for pediatric inpatients with melanocytic nevi.
CONCLUSIONS: Given the increasing number and relatively large hospitalization burden among children with melanocytic nevi hospitalized in
China, the government needs to pay more attention to this group and provide corresponding economic and policy support.