目的:本研究比较了经无气单侧腋下入路(ETGUA)和胸锁乳突前缘入路(SLEA)的内镜甲状腺切除术与传统的开放式甲状腺切除术(COT)在半甲状腺切除术中的应用。主要重点是保护颈部肌肉(胸锁乳突,表舌骨,胸骨甲状腺)以及通过这些常见方法产生的术后声音和吞咽功能。
方法:共纳入302例接受半甲状腺切除术的患者,分为三组:ETGUA(n=101),SLEA(n=100),和COT(n=101)。超声测量双侧颈部肌肉厚度,包括胸锁乳突,表舌骨,和胸甲.与非手术侧相比,手术侧的厚度变化。分析的因素包括肌肉厚度变化,吞咽障碍评分(SIS),语音障碍指数(VHI),疤痕宇宙评估和评级(SCAR),颈部损伤指数(NII)手术持续时间,排水量,住院治疗,和淋巴结的数量。
结果:除性别差异外,三组间临床特征一致,年龄,BMI。如胸锁乳突肌,NII,低钙血症,术后PTH,短暂的声音嘶哑,淋巴结数目三组间差异无统计学意义。然而,在手术时间上有显著差异,排水量,住院期间舌骨肌,胸骨舌骨肌,VHI,SIS,和SCAR(所有p<0.001)。
结论:与COT相比,ETGUA和SLEA在保护颈部肌肉和保持声音和吞咽功能方面表现出优越性,而不影响手术安全性或激进性。
OBJECTIVE: This study compares endoscopic thyroidectomy by gasless unilateral axillary approach (ETGUA) and sternocleidomastoid leading-edge approach (SLEA) with conventional open thyroidectomy (COT) in hemithyroidectomy. The main focus is on the protection of neck muscles (sternocleidomastoid, omohyoid, sternothyroid) and the postoperative function of voice and swallowing yielded through these common approaches.
METHODS: A total of 302 patients who underwent hemithyroidectomy were enrolled and divided into three groups: ETGUA (n = 101), SLEA (n = 100), and COT (n = 101). Ultrasound was used to measure the thickness of bilateral neck muscles, including the sternocleidomastoid, omohyoid, and sternothyroid. The changes in thickness on the surgical side compared to the non-surgical side. Analyzed factors included muscle thickness changes, Swallowing Impairment Score (SIS), Voice Handicap Index (VHI), Scar Cosmesis Assessment and Rating (SCAR), Neck Injury Index (NII), surgery duration, drainage volume, hospitalization, and number of lymph nodes.
RESULTS: The clinical characteristics among the three groups were consistent except for differences in sex, age, and BMI. Metrics such as sternocleidomastoid muscle, NII, hypocalcemia, postoperative PTH, transient hoarseness, and number of lymph nodes showed no significant differences among the three groups. However, significant differences were found in the duration of surgery, drainage volume, hospitalization period omohyoid muscle, Sternohyoid muscle, VHI, SIS, and SCAR (all p < 0.001).
CONCLUSIONS: In comparison to COT, ETGUA and SLEA demonstrate superiority in protecting neck muscles and preserving voice and swallowing function without compromising surgical safety or radicality.