NORM

NORM
  • 文章类型: Journal Article
    本文旨在对来自也门共和国13个不同地区的26篇发表的与自然放射性(NORM)和增强人工放射性(TENORM)研究有关的文章进行系统回顾。这项研究依赖于对各种样本类型的分析,包括空气,地下水地表水,温泉水,土壤,沙子,岩石,建筑材料,和油田样本。它还分析了研究领域,所用探测器的类型,和研究的时间表。分析结果引起了人们对许多研究区域中观察到的高水平放射性的关注。此外,一些地区表明没有任何先前的放射学研究,尽管对人口和环境有明显的影响,这表明存在潜在的放射性核素浓度。基于这项研究,强烈建议研究人员在先前长期研究的地区以及先前未进行放射学研究的地区进行进一步的放射学研究,以评估潜在的放射性核素浓度。
    This paper aimed to conduct a systematic review of 26 published articles from 13 different regions in the Republic of Yemen related to the study of natural radioactivity (NORM) and enhanced artificial radioactivity (TENORM). The study relied on the analysis of various sample types, including air, groundwater, surface water, hot spring water, soil, sand, rocks, building materials, and oil field samples. It also analyzed the study areas, the types of detectors employed, and the study\'s timeframe. The analytical results raised significant concerns regarding the high levels of radioactivity observed in many of the studied regions. Moreover, some regions indicated the absence of any prior radiological study, despite apparent effects on the population and the environment, which suggest the presence of potential radionuclide concentration. Based on this study, it is strongly recommended that researchers conduct further radiological studies in regions previously studied over extended periods and in areas where no prior radiological studies have been conducted to assess potential radionuclide concentration.
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  • 文章类型: Journal Article
    背景:确定药物-靶标相互作用(DTIs)在药物开发中起着关键作用。用于识别DTI的传统湿法实验是昂贵且耗时的。预测DTI的有效计算方法有助于加快药物发现的过程。提出了多种基于非负矩阵分解的DTI预测方法,但大多忽略了特征矩阵的稀疏性和所采用的矩阵分解算法的收敛性,因此,他们的性能可以进一步提高。
    结果:为了更准确地预测DTI,我们提出了一种新的方法iPALM-DLMF。iPALM-DLMF将DTIs预测建模为具有图对偶正则化项和[公式:参见文本]范数正则化项的非负矩阵分解问题。图对偶正则化项用于整合来自药物相似度矩阵和目标相似度矩阵的信息,和[公式:见正文]范数正则化项用于保证非负矩阵分解得到的特征矩阵的稀疏性。为了解决模型,iPALM-DLMF采用非负双奇异值分解初始化非负矩阵分解,和惯性近端交替线性化最小化迭代过程,已经证明收敛到KKT点,得到矩阵分解的最终结果。大量实验结果表明,iPALM-DLMF比其他最先进的方法具有更好的性能。在案例研究中,在由iPALM-DLMF预测的药物加巴喷丁靶向的50种得分最高的蛋白质中,已经验证了46个,在iPALM-DLMF预测的50种针对前列腺素-内过氧化物合酶2的得分最高的药物中,已经验证了47个。
    BACKGROUND: Identifying drug-target interactions (DTIs) plays a key role in drug development. Traditional wet experiments to identify DTIs are costly and time consuming. Effective computational methods to predict DTIs are useful to speed up the process of drug discovery. A variety of non-negativity matrix factorization based methods are proposed to predict DTIs, but most of them overlooked the sparsity of feature matrices and the convergence of adopted matrix factorization algorithms, therefore their performances can be further improved.
    RESULTS: In order to predict DTIs more accurately, we propose a novel method iPALM-DLMF. iPALM-DLMF models DTIs prediction as a problem of non-negative matrix factorization with graph dual regularization terms and [Formula: see text] norm regularization terms. The graph dual regularization terms are used to integrate the information from the drug similarity matrix and the target similarity matrix, and [Formula: see text] norm regularization terms are used to ensure the sparsity of the feature matrices obtained by non-negative matrix factorization. To solve the model, iPALM-DLMF adopts non-negative double singular value decomposition to initialize the nonnegative matrix factorization, and an inertial Proximal Alternating Linearized Minimization iterating process, which has been proved to converge to a KKT point, to obtain the final result of the matrix factorization. Extensive experimental results show that iPALM-DLMF has better performance than other state-of-the-art methods. In case studies, in 50 highest-scoring proteins targeted by the drug gabapentin predicted by iPALM-DLMF, 46 have been validated, and in 50 highest-scoring drugs targeting prostaglandin-endoperoxide synthase 2 predicted by iPALM-DLMF, 47 have been validated.
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  • 文章类型: Journal Article
    未经证实:儿童创伤问卷简表(CTQ-SF)是广泛使用的儿童虐待(CM)工具。然而,中国青少年CTQ-SF的心理测量特性和规范性数据仍然未知。
    UNASSIGNED:为了研究具有全国代表性的中国青少年样本中中文版CTQ-SF的心理测量特性和规范数据,包括内部一致性可靠性,测试-重测可靠性,结构有效性,和收敛有效性。
    UNASSIGNED:从中国五个省招募了20,951名12至18岁的青少年。对CTQ-SF的25个临床项目进行项目分析。进行验证性因子分析以检查因子结构的拟合指数。儿童不良经历量表(ACE)用于评估收敛效度。给出了CTQ-SF和每个子量表得分的百分位数排名。
    UNASSIGNED:根据项目分析中三种方法的结果,项目4应该删除。其余24个临床项目在替代的四因素模型中获得了令人满意的拟合。替代CTQ-SF显示出可接受的内部一致性,四个分量表的Cronbach'sα为0.824(忽略),0.755(性虐待)0.713(身体虐待),和0.666(情感虐待),分别。此外,替代CTQ-SF的重测信度和收敛效度也可以接受.
    UNASSIGNED:替代四因素模型CTQ-SF在中国青少年中表现出良好的信度和效度。此外,CTQ-SF的规范性信息可为确定不同亚型CM的严重程度提供实际支持.
    UNASSIGNED: The Childhood Trauma Questionnaire-Short Form (CTQ-SF) is a widely utilized instrument of childhood maltreatment (CM). However, psychometric properties and normative data of the CTQ-SF for Chinese adolescents are still unknown.
    UNASSIGNED: To examine psychometric properties and normative data of Chinese version CTQ-SF in a nationally representative sample of Chinese adolescents, including internal consistency reliability, test-retest reliability, structural validity, and convergent validity.
    UNASSIGNED: A total of 20,951 adolescents aged 12 to 18 years were recruited from five provinces across China. Item analysis was used for 25 clinical items of the CTQ-SF. Confirmatory factor analysis was performed to examine fit indices of the factor structure. The Adverse Childhood Experiences Scale (ACEs) was used to evaluate convergent validity. The percentile ranks for scores of the CTQ-SF and each subscales were presented.
    UNASSIGNED: According to the results of three methods in Item analysis, Item 4 should be dropped. The remaining 24 clinical items achieved satisfactory fits in an alternative four-factor model. The alternative CTQ-SF showed acceptable internal consistency and the Cronbach\'s α of the four subscales was 0.824 (Neglect), 0.755 (Sexual Abuse), 0.713 (Physical Abuse), and 0.666 (Emotional Abuse), respectively. Besides, test-retest reliability and convergent validity of the alternative CTQ-SF were also acceptable.
    UNASSIGNED: The alternative four-factor model CTQ-SF exhibits good reliability and validity among Chinese adolescents. Additionally, the normative information of the CTQ-SF could provide practical support for determining severity of different subtypes of CM.
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  • 文章类型: Journal Article
    背景:患有听觉处理缺陷的儿童可能会面临语言问题,学习,和社会交往。
    目的:编制中国学龄前儿童听觉加工评价量表并建立量表的规范。
    方法:通过文献综述形成量表的预测版本,定性访谈,专家咨询,和一个小样本的预测试。采用分层整群抽样方案选取南京市9所幼儿园。首先,选取来自两所幼儿园的734名儿童进行量表的大样本预测试。然后,选取4所幼儿园的1526名儿童和3所幼儿园的1151名儿童进行信度和效度分析和验证性因子分析,分别。以9所幼儿园的3411点量表数据为基础,建立量表的标准化规范数据。最后,通过比较量表上评分提示的正常和异常听觉处理儿童的客观听觉处理测试结果,分析量表的临床有用性。
    结果:学龄前听觉处理评估量表包括5个维度和30个项目。该标度的Cronbach'salpha值大于0.9。验证性因子分析结果验证了量表结构的合理性。建立了量表的百分位数标准。正常和异常听觉处理组的电生理检查结果差异有统计学意义(P<0.05)。
    结论:开发的学前听觉加工评估量表具有良好的信度和效度。该尺度适于临床运用。
    BACKGROUND: Children with auditory processing deficits may face problems with language, learning, and social communication.
    OBJECTIVE: To develop a Chinese auditory processing assessment scale for preschool children and establish the norms of the scale.
    METHODS: The predictive version of the scale was formed by a literature review, qualitative interviews, expert consultation, and a pre-test with a small sample. Nine kindergartens in Nanjing were selected by a stratified cluster sampling plan. First, 734 children from two kindergartens were selected for the large sample pre-test of the scale. Then, 1526 children from four kindergartens and 1151 children from three kindergartens were selected for the reliability and validity analysis and confirmatory factor analysis, respectively. The standardized norm data of the scale were established based on the 3411 points of scale data of the nine kindergartens. Finally, the clinical usefulness of the scale was analyzed by comparing the results of objective auditory processing tests in children with normal and abnormal auditory processing prompted by the score on the scale.
    RESULTS: The preschool auditory processing assessment scale includes 5 dimensions and 30 items. The Cronbach\'s alpha value of the scale is greater than 0.9. The confirmatory factor analysis results verify that the scale structure is reasonable. The percentile norm of the scale was established. The results of electrophysiological tests of the normal and abnormal auditory processing groups were statistically different (P < 0.05).
    CONCLUSIONS: The developed preschool auditory processing assessment scale has good reliability and validity. The scale is suitable for clinical application.
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  • 文章类型: Journal Article
    Objective: To establish the Core Occupational Stress Scale (COSS) norm values for manufacturing and medical workers. Methods: A total of 10 316 manufacturing workers of 20 companies from 7 provincial capital cities and 5 031 medical workers of 19 hospitals from 4 provincial capital cities were investigated using a stratified sampling method. Questionnaire information including occupational stress was collected. Norms of mean, percentile and T scores were calculated for COSS total and sub-dimension scores by different demographic characteristics. Based on the normal distribution, cut points of x¯+0.5s, x¯+s, x¯+1.5s of COSS total scores were calculated to classify the degree of occupational stress. Results: The COSS total scores were (45.48±8.16) and (45.71±8.46). The 50th percentiles were both 46, and T score ranges were (15-92) and (16-91), respectively, for manufacturing and medical workers. When the total score was<50, 50-53, 54-57, and >57 for manufacturing worker, or<50, 50-54, 55-58, and >58 for medical workers, occupational stress would be classified into none, mild, moderate, and severe levels. Conclusion: Compatible with the national condition of China, as well as the principles of psychological measurement, these norm values for manufacturing and medical workers could provide theoretical support and practical guideline on occupational mental health promotion.
    目的: 研制适用于我国制造业工人和医务人员的职业紧张测量核心量表(COSS)得分常模。 方法: 采用分层随机抽样方法,从制造业高度聚集区域7个省会市20家制造业企业和全国东、中、西部地区4个省会市19家医院分别抽取制造业工人(10 316名)和医务人员(5 031名)作为常模样本。通过问卷收集职业紧张相关信息,并建立不同人口学特征对象的均数常模、百分位常模、T分值常模,同时采用正态分布法,以COSS总分的x¯+0.5s、x¯+s、x¯+1.5s作为职业紧张程度划分标准。 结果: 制造业工人、医务人员COSS总分分别为(45.48±8.16)、(45.71±8.46)分,P50对应的总分均为46,T分常模范围分别为(15~92)、(16~91)分。当制造业工人COSS总分<50、50~53、54~57、>57分时,医务人员COSS总分<50、50~54、55~58、>58分时,分别判定为无职业紧张和轻度、中度、重度职业紧张水平。 结论: 本常模符合我国国情及心理学测量要求,操作简便、易行,为制造业工人和医务人员心理健康促进提供理论支持与实践指导。.
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  • 文章类型: Journal Article
    Occupational stress is one of the major occupational health problems in industrialized countries. In Europe, the United States, Japan, and other countries, occupational stress has been included in the prevention and control of occupational hazards in the workplace. This problem has also become a major risk factor affecting the physical and mental health of the working population in China. Over the last three decades, China had carried out a lot of research on occupational stress and made significant progress, but there is still a big gap between China and industrialized countries in terms of theoretical research on occupational stress, development of measurement tools, research topics and methods, formulation of regulations and standards, and practice of prevention and control. Articles in this key issue report the research on the core scale of occupational stress measurement for the Chinese working population, the scale scoring norm of manufacturing and medical personnel, the research on the relationship between positive psychology variables, and occupational stress and its role in the relationship between occupational stress and health outcomes.
    职业紧张是工业化国家主要的职业卫生问题之一,欧洲、美国、日本等已经将其纳入工作场所职业危害因素预防控制范围,职业紧张也已经成为影响我国职业人群身心健康的主要危险因素。过去30年,我国在职业紧张方面开展了很多研究,取得了显著的进步,但在职业紧张理论研究、测量工具研制、研究内容和方法、法规与标准制定以及预防控制实践方面与工业化国家相比,仍有很大差距。本期重点号报道了适用于我国职业人群的职业紧张测量核心量表以及制造业工人和医务人员两个人群的量表评分常模研究,和积极心理学变量与职业紧张关系以及其在职业紧张与健康结局关系中作用的研究等。.
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  • 文章类型: Journal Article
    抑郁症的大规模筛查一直使用在给定时间根据给定人群制定的规范。研究人员试图随着时间和不同人群调整截止分数,但是这种努力太少了,而且远远不能对时间和区域变化敏感。在这项研究中,我们提出了一种无监督的机器学习方法来构建抑郁分类,以克服传统的基于规范的方法的局限性。数据来自8,063名中国初中和高中学生。使用k均值聚类,我们生成了4个级别的抑郁症状,以匹配基于常模的分类.然后,我们通过将它们与基于规范的方法(及其变化)在鲁棒性方面进行比较来评估分类的有效性,模型性能(精度,AUC,和灵敏度),和收敛结构有效性(即,具有已知相关性的协会)。结果表明,与基于规范的方法相比,我们的自动分类系统表现良好。
    Large-scale screening for depression has been using norms developed based on a given population at a given time. Researchers have attempted to adjust the cutoff scores over time and for different populations, but such efforts are too few and far in between to be sensitive to temporal and regional variations. In this study, we proposed an unsupervised machine learning approach to constructing depression classifications to overcome the limitations of the traditional norm-based method. Data were collected from 8,063 Chinese middle and high school students. Using k-means clustering, we generated four levels of depressive symptoms to match the norm-based classifications. We then evaluated the validity of the classifications by comparing them with the norm-based method (and its variations) in terms of their robustness, model performance (accuracy, AUC, and sensitivity), and convergent construct validity (i.e., associations with known correlates). The results showed that our automatic classification system performed well as compared to the norm-based method.
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  • 文章类型: Journal Article
    By introducing independent parameters and interval variables, applying the weight functions and the technique of real analysis, an extended Hilbert\'s integral inequality in the whole plane with parameters and a best possible constant factor is provided. The equivalent forms, the reverses, and the related homogeneous forms with particular parameters are considered. Meanwhile, an extended Hilbert\'s integral operator in the whole plane is defined, and the operator expressions for the equivalent inequalities are obtained.
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  • 文章类型: Journal Article
    副作用(SEE)是一种观察,即人们对行为是否有意的直觉取决于结果是好还是坏。不对称的反应,然而,并不代表所有受试者的判断(尼科尔斯和乌拉托夫斯基,2007).对于可以调节SEE大小的主观因素,它仍未被探索。因此,当前的研究调查了个体相关因素是否,具体来说,成年人关心某人行为结果的强度是否会影响他们对该人是否打算结果的判断。我们假设参与者对虚构代理人的判断对其行为副作用的责任将取决于他们对副作用领域的关心程度。在两个实验中,照顾受影响的参与者的强度将意向归为代理人的负面意外副作用。与积极的副作用相比,故意对负面副作用的归因更强(即,SEE;Knobe,2003)仅在参与者报告较高的关怀水平的领域中发现。此外,关怀的强度增加了意图归因可靠的负面副作用,而不是正面副作用。这些结果表明,关心一个领域会介导对意图的不对称归因,而不是积极的副作用。
    The side-effect effect (SEE) is the observation that people\'s intuition about whether an action was intentional depends on whether the outcome is good or bad. The asymmetric response, however, does not represent all subjects\' judgments (Nichols and Ulatowski, 2007). It remains unexplored on subjective factors that can mediate the size of SEE. Thus, the current study investigated whether an individual related factor, specifically, whether adults\' intensity of caring about an outcome of someone\'s actions influences their judgments about whether that person intended the outcome. We hypothesized that participants\' judgments about fictional agents\' responsibility for their action\'s side-effects would depend on how much they care about the domain of the side-effect. In two experiments, the intensity of caring affected participants\' ascription of intention to an agent\'s negative unintended side-effect. The stronger ascription of intentionality to negative than positive side-effects (i.e., the SEE; Knobe, 2003) was found only in domains in which participants reported higher levels of caring. Also, the intensity of caring increased intentionality attributions reliably for negative side-effects but not for positive side-effects. These results suggest that caring about a domain mediates an asymmetrical ascription of intentionality to negative more than positive side-effects.
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  • 文章类型: Journal Article
    The GNSS/INS (Global Navigation Satellite System/Inertial Navigation System) navigation system has been widely discussed in recent years. Because of the unique INS-aided loop structure, the deeply coupled system performs very well in highly dynamic environments. In practice, vehicle maneuvering has a big influence on the performance of IMUs (Inertial Measurement Unit), and determining whether the selected IMUs and receiver parameters satisfy the loop dynamic requirement is still a critical problem for deeply coupled systems. Aiming at this, a new parameter self-calibration method based on the norm principle is proposed which explains the relationship between IMU precision and the velocity error of the system; the method will also provide a detailed solution to calculate the loop steady-state tracking error, so it will eventually make a judgment about the stability of the tracking loop under present system parameter settings. Lastly, a full digital simulation platform is set up, and the results of simulations show good agreement with the proposed method.
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