■本研究利用全球疾病负担(GBD)2019年的数据,评估了1990年至2019年期间由环境颗粒物污染引起的缺血性中风的全球影响。
■对各个亚组进行了分析,包括区域,社会人口指数(SDI)水平,国家,年龄,和性别。这项研究主要检查了死亡病例等指标,死亡率,残疾调整寿命年(DALYs),DALY费率,和年龄标准化指标。计算估计年度百分比变化(EAPC)以评估随时间的趋势。
■研究发现,由于周围的颗粒物,缺血性中风的全球负担适度增加,年龄标准化的DALY率显示EAPC为0.41。亚组分析表明,撒哈拉以南非洲西部的增长最为显著(EAPC2.64),东亚(EAPC2.77),和东部撒哈拉以南非洲(EAPC3.80)。中低SDI国家表现出最显著的上升趋势,年龄标准化死亡率(ASDR)和DALY率的EAPC值为3.36和3.58,分别。具体来说,像赤道几内亚这样的国家,东帝汶,也门的ASDR和年龄标准化的DALY比率增幅最大。此外,由于颗粒物引起的缺血性卒中的死亡率和DALY率在所有地区均显示随着年龄的增加而显著增加.
■该研究强调了与颗粒物污染有关的缺血性中风对全球健康的影响日益增加,特别是在亚洲和非洲。这强调了在这些地区进行量身定制的公共卫生干预措施的关键必要性。
UNASSIGNED: This study assesses the worldwide impact of ischemic stroke caused by ambient particulate matter pollution between 1990 and 2019, utilizing data from the Global Burden of Disease (GBD) 2019.
UNASSIGNED: An analysis was conducted across various subgroups, including region, Socio-demographic Index (SDI) level, country, age, and gender. The study primarily examined metrics such as death cases, death rate, Disability-Adjusted Life Years (DALYs), DALY rate, and age-standardized indicators. The Estimated Annual Percentage Change (EAPC) was calculated to assess trends over time.
UNASSIGNED: The study found a moderate increase in the global burden of ischemic stroke attributed to ambient particulate matter, with the age-standardized DALY rate showing an EAPC of 0.41. Subgroup analyses indicated the most substantial increases in Western Sub-Saharan Africa (EAPC 2.64), East Asia (EAPC 2.77), and Eastern Sub-Saharan Africa (EAPC 3.80). Low and middle SDI countries displayed the most notable upward trends, with EAPC values of 3.36 and 3.58 for age-standardized death rate (ASDR) and DALY rate, respectively. Specifically, countries like Equatorial Guinea, Timor-Leste, and Yemen experienced the largest increases in ASDR and age-standardized DALY rate. Furthermore, both death and DALY rates from ischemic stroke due to particulate matter showed significant increases with age across all regions.
UNASSIGNED: The study highlights the increasing worldwide health consequences of ischemic stroke linked to particulate matter pollution, particularly in Asia and Africa. This emphasizes the critical necessity for tailored public health interventions in these regions.