Objective: To analyze the mechanism of invasive blood pressure change in radial artery caused by arm elevation by observing pressure, velocity and diameter of radial artery. Methods: Twenty-six hemodynamically stable hepatobiliary surgery patients admitted to the intensive care unit from June to December 2018 after general anesthesia in Tsinghua Changgung Hospital were selected. When the arm was raised, the invasive blood pressure was recorded, and the inner diameter and blood flow velocity of the radial artery were measured by Doppler ultrasound. The data following a normal distribution were compared with paired t test. Results: After arm elevation for 30 s, systolic blood pressure of radial artery decreased and diastolic blood pressure increased significantly((107±16) mmHg vs (120±17) mmHg, (75±6) mmHg vs (71±9) mmHg, t=25.0, -12.6, both P<0.05), but there was no significant difference in mean arterial pressure ((87±10) mmHg vs (87±11) mmHg, t=1.1, P>0.05). The peak velocity, end-diastolic velocity and resistance index of the radial artery increased significantly, and the transverse and longitudinal inner diameters of the radial artery decreased significantly after the arm was elevated for 30 s (t=-63.4, -14.6, -22.5, 31.4, 25.3, all P<0.01). Conclusions: Kinetic pressure compensation and vascular resistance compensation may be the main mechanism of radial artery pressure change when the arm is elevated. Arm elevation can be used as a vascular resistance response test clinically.
目的: 通过观测桡动脉压力、流速、直径等指标,分析抬高上肢导致桡动脉有创血压改变的流体力学机制。 方法: 选择2018年6至12月期间入住清华长庚医院重症监护病房(ICU)的血流动力学稳定的肝胆外科全身麻醉手术后患者26例。分别在抬高上肢前和抬高上肢时,记录有创血压数值,并以多普勒超声测量桡动脉置管处的动脉血管内径和血流速。符合正态分布的数据比较采用配对t检验。 结果: 与抬高上肢前相比,抬高上肢30 s后桡动脉收缩压下降、舒张压上升,分别为(107±16) mmHg比(120±17) mmHg和(75±6) mmHg比(71±9) mmHg,差异均有统计学意义(t=25.0、-12.6,均P<0.05),但平均动脉压变化差异无统计学意义[(87±10) mmHg比(87±11) mmHg,t=1.1,P>0.05]。与抬高上肢前相比,抬高上肢30 s后桡动脉收缩期峰流速、舒张期末流速和阻力指数均显著增加,而桡动脉横径与纵径则显著减小,前后比较差异均有统计学意义(t=-63.4、-14.6、-22.5、31.4、25.3,均P<0.01)。 结论: 动压代偿和血管阻力代偿可能是抬高上肢时桡动脉压力改变的主要机制,抬高上肢可以作为血管阻力反应性试验在临床应用。.