Abstract：
Calibration affects central blood pressure (BP) estimation accuracy. Factors influencing the accuracy of noninvasive central BP measurement, type of calibration method implemented (systolic/diastolic BP or mean/diastolic BP), and type of BP measurement device used (devices using the transfer function method, directly measurement from the carotid artery, and the transfer function-like method), were investigated. Fifty participants (aged 62.4 ± 8.9 years) without overt heart diseases were recruited. Invasive aortic and radial BP was measured. Simultaneously, noninvasive central BP was measured using three types of devices. The mean invasive aortic BP was 127 ± 19/95 ± 14 mmHg. Noninvasive central BP tended to be slightly lower than invasive BP, though without statistical significance. The type of calibration method did not significantly influence the noninvasive cSBP measurements (p ≥ 0.24). Results from cuff-based devices were significantly lower than invasive measurements (p = 0.04). Multiple regression analyses showed that gender was significantly correlated with the accuracy of noninvasive cSBP measurement. In conclusion, noninvasive cSBP measurements are comparable to invasive measurements but might underestimate true cSBP. The type of device may affect the accuracy of measurement. Either of the two calibration methods is acceptable.
摘要：
校准影响中心血压(BP)估计准确性。影响无创中心血压测量准确性的因素，实施的校准方法类型(收缩压/舒张压或平均/舒张压)，和使用的BP测量设备的类型(使用传递函数法的设备，从颈动脉直接测量，和类似传递函数的方法)，被调查了。招募了50名没有明显心脏病的参与者（年龄为62.4±8.9岁）。测量有创主动脉和桡动脉血压。同时,使用三种类型的装置测量非侵入性中枢BP.平均有创主动脉血压为127±19/95±14mmHg。非侵入性中枢BP倾向于略低于侵入性BP，但没有统计学意义。校准方法的类型对无创cSBP测量没有显着影响（p≥0.24）。基于袖带的设备的结果显着低于侵入性测量（p=0.04）。多元回归分析表明，性别与非侵入性cSBP测量的准确性显着相关。总之,非侵入性cSBP测量与侵入性测量相当,但可能低估了真实的cSBP.设备的类型可能会影响测量的准确性。两种校准方法中的任一种都是可接受的。
