BACKGROUND: Evidence supports the effectiveness of serious games in health education, but little is known about their effects on the psychosocial well-being of children in the general population.
OBJECTIVE: This study aimed to investigate the potential of a mobile game-based safety education program in improving children\'s safety and psychosocial outcomes.
METHODS: Safe City is a mobile roleplaying game specifically designed to educate children in Hong Kong about safety. This randomized controlled trial included 340 children in grades 4 through 6. Intervention arm participants (n=170) were instructed to play the Safe City mobile game for 4 weeks, whereas control arm participants (n=170) received a safety booklet. All participants completed a survey on safety knowledge and behaviors and psychosocial problems at baseline (T1), 1 month postintervention (T2), and 3 months postintervention (T3). Cumulative game scores and mini-game performance were analyzed as a proxy for the extent of exposure to the game. Outcome data were analyzed using 2-sample 2-tailed t tests to compare mean change from T1 to T2 and to T3 for intervention versus control arm participants. The association of game use with outcome changes postintervention was analyzed using generalized additive models.
RESULTS: No significant differences were found in mean changes between the intervention and control arms. However, use analyses showed that higher game scores were associated with improvements in safe behavior (P=.03) and internalizing problems (P=.01) at T3. Matching and Spot the Danger mini-game performance significantly predicted improvements in safety knowledge at T2 and T3.
CONCLUSIONS: Analysis of use has shown that playing the Safe City mobile game can result in significant improvements in safety knowledge and reductions in unsafe behavior and internalizing problems. These findings provide evidence for the positive impact of serious games on psychological and social well-being, highlighting the potential of technology-driven interventions to assist children in learning about safety and preventing injuries.
BACKGROUND: ClinicalTrials.org NCT04096196; https://clinicaltrials.gov/show/NCT04096196.
UNASSIGNED: RR2-10.2196/17756.

Drinking water is the main cause of iodine excess among Chinese residents and we have found that water iodine concentration (WIC) reduction was the effective intervening measure. In this study, to eliminate the hazards of water-borne excessive iodine, we firstly investigated the WIC of villages in Tianjin in 2017 to determine the distribution range. Secondly, the risk characterization of excessive iodine on residents in 6∼< 9 years old, 9∼< 12 years old, 12∼< 15 years old, 15∼< 18 years old and adults were evaluated, and the safe upper limit of WIC was determined. Finally, WIC was investigated again after the completion of WIC reduction in water-borne excessive-iodine villages in 2020, and the differences in urinary iodine concentration (UIC) and thyroid volume (Tvol) of children aged 8-10 years before and after WIC reduction were analyzed. The WIC of 2459 villages surveyed was 22.30 (8.60-58.80) μg/L and the maximum was 514 μg/L. There were 422 villages with WIC > 100 μg/L. Under the conditions of non-iodized salt intake, recommended amount of iodized salt intake and actual amount intake, the maximum of excessive iodine exposure hazard quotient (HQ) were the highest in the age group of 6∼< 9 years, which were 2.300, 2.663 and 2.771, the safe upper WIC limits were 223 μg/L, 142 μg/L and 118 μg/L and villages with HQ> 1 accounted for 4.14%, 6.09% and 6.88% of all villages, respectively. After the WIC reduction, the WIC of the former water-borne iodine-excess villages decreased to < 100 μg/L, and the UIC and Tvol of children decreased (both P < 0.001) and was within normal range. Determining the distribution range of water-borne iodine-excess areas, exploring appropriate intervening measure, carrying out risk assessment, determining the WIC safe upper limit, intervening and evaluating the intervention effect can be the process to eliminate the hazards of water-borne excessive iodine.

Celluloid, the predecessor to plastic, was synthesized in 1869, and due to technological advancements, plastic products appear to be ubiquitous in daily life. The massive production, rampant usage, and inadequate disposal of plastic products have led to severe environmental pollution. Consequently, reducing the employment of plastic has emerged as a pressing concern for governments globally. This review explores microplastics, including their origins, absorption, and harmful effects on the environment and humans. Several methods exist for breaking down plastics, including thermal, mechanical, light, catalytic, and biological processes. Despite these methods, microplastics (MPs, between 1 and 5 mm in size) continue to be produced during degradation. Acknowledging the significant threat that MPs pose to the environment and human health is imperative. This form of pollution is pervasive in the air and food and infiltrates our bodies through ingestion, inhalation, or skin contact. It is essential to assess the potential hazards that MPs can introduce. There is evidence suggesting that MPs may have negative impacts on different areas of human health. These include the respiratory, gastrointestinal, immune, nervous, and reproductive systems, the liver and organs, the skin, and even the placenta and placental barrier. It is encouraging to see that most of the countries have taken steps to regulate plastic particles. These measures aim to reduce plastic usage, which is essential today. At the same time, this review summarizes the degradation mechanism of plastics, their impact on human health, and plastic reduction policies worldwide. It provides valuable information for future research on MPs and regulatory development.

Thiophenol (PhSH), a highly reactive aromatic thiol, plays an essential role as a common industrial raw material in food, pesticides, pharmaceuticals, and cosmetics. In this work, we designed and constructed two fluorescent probes CM-PhSH and CM-Ratio-PhSH by a rational strategy. Specifically, coumarin fluorophores with excellent optical properties were modified, and olefinic unsaturated bonds served as reaction sites for the detection of PhSH. Based on this, the introduction of the nitro group at specific positions of the CM-PhSH changed the fluorescence emission of the CM-Ratio-PhSH, eventually obtaining a novel ratiometric fluorescent probe CM-Ratio-PhSH for PhSH detection. Surprisingly, these two probes exhibited advantages such as high specificity and low limit of detection (LOD) for CM-PhSH 32.3 nM and CM-Ratio-PhSH 40.2 nM, respectively. Furthermore, subsequent experiments demonstrated CM-PhSH and CM-Ratio-PhSH could be successfully used for highly selective and rapid detection of PhSH in aqueous solutions, live cells, and complex food samples.

The long-term and excessive use of organophosphorus pesticides (OPs) leads to hazardous residues in the environment, which threatens human health to a considerable extent. Colorimetric methods can quickly and readily identify pesticide residue, but they still have various challenges in accuracy and stability. Herein, a smartphone-assisted and non-enzymatic colorimetric biosensor was constructed for rapid monitoring of multiple OPs based on the enhanced effect of aptamer on the catalytic ability of octahedral Ag2O. It was demonstrated that the aptamer sequence could enhance the affinity of colloidal Ag2O to chromogenic substrates, and accelerate the generation of oxygen radicals such as superoxide radical (·O2-) and singlet oxygen (1O2) from dissolved oxygen, thereby significantly increasing the oxidase activity of octahedral Ag2O. The color change of the solution can be easily converted to the corresponding RGB values by a smartphone for quantitative and rapid detection of multiple OPs. Hence, the smartphone-based and visual biosensor of multiple OPs was acquired with limit of detection of 10 μg L-1, 28 μg L-1 and 40 μg L-1 for isocarbophos, profenofos and omethoate, respectively. The colorimetric biosensor also exhibited good recoveries in several environmental and biological samples, showing that it may have broad application prospects for detecting OPs residues.

Microplastic pollution has become an emergent global environmental issue because of its ubiquitous nature and everlasting ecological impacts. In marine ecosystems, microplastics can serve as carriers to absorb various contaminants and the ingestion of microplastics in oysters is of concern because they can induce several adverse effects. The analytical process of microplastics in oysters commonly consists of separation, quantification, and identification. Quantification of microplastics is difficult since information regarding the analytical methods is incoherent, therefore, standard microplastic analytical methods for shellfish should be established in the future. The depuration process can be used to reduce the level of microplastics in oysters to ensure safe consumption of oysters and longer depuration time facilitates improved depuration efficacy. In summary, this review aims to help better understand microplastic pollution in oysters and provide useful suggestions and guidance for future research.

At present, diesel vehicles still play an irreplaceable role in the traditional energy field in China. Diesel vehicle exhaust contains hydrocarbons, carbon monoxide, nitrogen oxides, and particulate matter, which can lead to haze weather, photochemical smog, and the greenhouse effect; endanger human health; and damage the ecological environment. In 2020, the number of motor vehicles in China reached 372 million, and the number of automobiles reached 281 million, of which 20.92 million are diesel vehicles, accounting for only 5.6% of the number of motor vehicles and 7.4% of the number of automobiles. Nevertheless, diesel vehicles emitted 88.8% of nitrogen oxides and 99% of particulate matter in total vehicle emissions. Diesel vehicles, especially diesel trucks, have become the top priority of motor vehicle pollution control. However, there are few reviews on the comprehensive treatment of diesel vehicle exhaust. This review provides an overview of exhaust gas composition, hazards, and treatment techniques. Phytoremediation, three-way catalytic conversion, rare earth catalytic degradation, and nanoscale TiO2 catalytic degradation are briefly described.

UNASSIGNED: This study developed a nano-filter to reduce the concentration of hazardous substances in surgical smoke.
UNASSIGNED: The nano-filter consists of nanomaterials and hydrophilic materials. Smoke was collected before and after using the new nano-filter during the surgery.
RESULTS: The concentration of PM2.5 and PAHs produced by the monopolar device was the highest (P < .05). The concentration of PM2.5 and PAHs after using a nano-filter was less than the non-filter group (P < .05).
RESULTS: Surgical smoke generated by monopolar and bipolar devices pose a potential cancer risk to health staff in the operational room. The concentration of PM and PAHs were reduced and the cancer risk was not obvious by using the nano-filter.

Due to environmental pollution, crop growth and productivity are threatened at different levels. Recapitulation of changes in plant bodies due to water pollution and mitigating strategies reveal the need for précised actions to save crop losses. The present study was carried out to estimate modulations in growth, mineral homeostasis, and nutrient profile of fruits in Capsicum annum L. grown with three concentrations of wastewater (25, 50, 100%) and two levels of silver nanoparticles (40 and 80 mg/L AgNPs). It has been reported that ion accumulation patterns from wastewater clearly vary among crops. Our findings manifested that the application of AgNPs significantly improved the mineral ions in different plant tissues, that ultimately helped to improve growth. Highest improvements were recorded for root shoot P (316 and 197%) at T9 (80 mg/L AgNPs + normal water), while K (273 and 262%), Mg (638 and 916%), and Ca (148 and 273%), at T11 (80 mg/L AgNPs + 50% Wastewater), in comparison with control. Such reduction in elemental uptake that remain detrimental even at low concentrations positively correlates with growth and nutrition of Capsicum plants. Another facet of our observation is dose-dependent improvement in nutritive attributes of fruits i.e., crude fibers, proteins, and carbohydrates by AgNPs. T8 (40 mg/L AgNPs + 100% Wastewater), improved nutritional attributes such as P (55%), Mn (44%), Zn (38%), Carbohydrates (62%), Crude fat (38%), and Fibers (49%) as compared to control. Application of silver nanoparticles (AgNPs) combined with untreated wastewater (WW) reduced the hazards of contaminants in plants. The finding of the current study suggested that AgNPs are a cost-efficient and environment friendly material having the potential to mitigate harmful impacts of WW on plants.

BACKGROUND: The construction of a safety culture in coal mine enterprises is an essential component of coal mine safety management. Current studies do not address the mechanism for forming and constructing systems for coal mine enterprise safety culture, and many studies are based on imperfect theoretical frameworks and unsystematic empirical research, their policy recommendations are not systematic or operable, and they offer no feasible safety culture construction system.
OBJECTIVE: This study is devoted to analysing the theoretical basis of safety culture construction in coal mine enterprises from the perspective of hazards and proposing the content, stages and targets of constructing a safety culture and develops pragmatic approaches for coal mining enterprises to improve safety culture.
METHODS: A theoretical basis for safety culture construction in coal mine enterprises is proposed from the perspective of hazards by considering accident-causing mechanisms based on hazards. Furthermore, this study applied the case analysis and application to conduct empirical research on the proposed theoretical basis for safety culture construction from the perspective of hazards.
RESULTS: Four aspects are proposed to capture the content and objectives of safety culture construction from the perspective of hazards: safety concept, behaviour safety, material state safety, and safety institutions. Furthermore, this paper provides a case study of safety culture construction by the Yimei coal group from the perspective of hazards, identifies the hazards based on the above four aspects, and then identifies preventative measures and controls for the identified hazards.
CONCLUSIONS: Constructing a safety culture in coal mine enterprises from the perspective of hazards is operable and practical, and thus this study provides essential theoretical and practical value for improving coal mine safety.