背景:剥夺性弱视在阻塞视轴的增生性持续性瞳孔膜(PPM)中是一个非常值得关注的问题。其他眼部异常可能伴随并进一步阻碍婴儿的视觉发育。我们评估了早期手术干预和及时视觉康复治疗的密集PPM和其他相关异常患者的长期视觉预后和并发症。
方法:回顾性回顾了2000年至2020年手术切除PPM并接受视觉康复的患者的病历。除了视轴阻塞PPM,纳入合并其他弱视危险因素或眼部异常的患者。由于如果存在潜在的白内障,为随后的晶状体摘除做准备,包括器械和伤口方向在内的手术设置与白内障手术相似.所有患者均尽快纳入视觉康复计划。结果包括性别,年龄,操作时间,初始和最终视力,屈光不正,并记录并发症。
结果:本病例系列包括5例患者中的7例。手术的平均年龄为42.3±21.1个月(范围,5至66个月),术后随访期为4.9年(范围,1.2至8.2年)。手术时患者年龄为2.5个月至2.5岁(平均,14个月)。术后平均随访5.3年(范围,2.5-8年)。没有术中和术后并发症。最终BCVA的平均值为0.29logMAR(范围,0到1logMAR)。屈光不正和斜视的相关眼部异常导致最佳的视觉预后。
结论:在PPM患者中,使用我们的技术,所有患者均无明显并发症.手术设置更容易处理并且更熟悉儿科外科医生。除了修补剥夺之外,对于有屈光不正性和斜视性弱视风险的患者,早期PPM干预和及时的视觉康复可达到最佳的视觉预后。
背景:本次回顾展,介入病例系列研究于2000年4月1日至2020年4月31日在中国医科大学附属医院进行。(IRB编号:CMUH109-REC2-069)。
BACKGROUND: Deprivation amblyopia is a great concern in hyperplastic persistent pupillary membranes (PPM) which blocked visual axis. Other ocular abnormality may accompany and further hinder the visual development of the infants. We evaluate the long-term visual prognosis and complications in patients with dense PPM and other associated abnormalities treated with early surgical intervention and timely visual rehabilitation.
METHODS: Medical records of patients with surgical removal of PPM from 2000 to 2020 and also receiving visual rehabilitation were retrospectively reviewed. Besides visual axis blocked PPM, patients combined with other amblyopic risk factors or ocular abnormalities were included. Due to preparation for subsequent lens extraction if an underlying cataract was present, the surgical settings including the instruments and wound direction were similar to cataract surgery. All patients were enrolled in a visual rehabilitation program as soon as possible. The results including sex, age, timing of operation, initial and final visual acuity, refractive errors, and complications were recorded.
RESULTS: Seven cases of five patients were included in this
case series. Mean age at surgery was 42.3 ± 21.1 months (range, 5 to 66 months) and the post-operative follow-up period was 4.9 years (range, 1.2 to 8.2 years). The patient age at time of surgery ranged from 2.5 months to 2.5 years (mean, 14 months). Mean postoperative follow-up was 5.3 years (range, 2.5-8 years). There were no intra-operative and post-operative complications. Final BCVA varied with a mean value of 0.29 logMAR (range, 0 to 1 logMAR). An associated ocular abnormality of ametropia and strabismus led to the best visual prognosis.
CONCLUSIONS: In patients with PPM, there were no significant complications in any patient using our technique. The surgical settings are easier to handle and more familiar with pediatric surgeons. Besides deprivation with patching, early PPM intervention and timely visual rehabilitation achieve the best visual prognosis in patients associated with risk of ametropic and strabismic amblyopia.
BACKGROUND: This retrospective, interventional
case series study was conducted at China Medical University Hospital between April 1, 2000 and April 31, 2020. (IRB number: CMUH109-REC2-069 ).