vertigo

眩晕
  • 文章类型: Journal Article
    急性眩晕被定义为在没有实际运动的情况下对自己或周围环境的运动的感知,这是急诊科入院的常见原因。此类症状的医疗资源利用率和住院时间较高。此外,急性期脑成像效率较低,考虑到CT和MRI对诊断作为中枢型眩晕病因的疾病的敏感性有限。在阴性结果的情况下,依靠影像学检查可能会提供错误的保证,或者不当延长院内检查。另一方面,临床检查,特别是对眼球震颤特征的评估,已被证明是高度准确和高效的由专家执行。文献数据指出,急诊医生通常没有使用这些技能或错误地使用它们。近年来,已经引入了几种临床算法,目的是提高急诊医师在评估这种特定病理时的诊断准确性。无论是“HINTS”和“STANDING”算法都经过了急诊医师手中的外部验证,显示出良好的诊断准确性。这份共识文件的目的是提供科学证据,支持医生在急诊科评估成年急性眩晕患者的临床决策。特别是在没有明确相关神经系统体征的情况下。该文件旨在提供一种直接和多学科的方法。同时,它试图划定制定本地诊断和治疗途径的基准,并为培训和研究计划的发展提供基础。
    Acute vertigo is defined as the perception of movement of oneself or the surroundings in the absence of actual motion and it is a frequent cause for emergency department admissions. The utilization of medical resources and the duration of hospital stay for this kind of symptom is high. Furthermore, the efficiency of brain imaging in the acute phase is low, considering the limited sensitivity of both CT and MRI for diagnosing diseases that are the causes of central type of vertigo. Relying on imaging tests can provide false reassurance in the event of negative results or prolong the in-hospital work-up improperly. On the other hand, clinical examinations, notably the assessment of nystagmus\' features, have proven to be highly accurate and efficient when performed by experts. Literature data point out that emergency physicians often do not employ these skills or use them incorrectly. Several clinical algorithms have been introduced in recent years with the aim of enhancing the diagnostic accuracy of emergency physicians when evaluating this specific pathology. Both the \'HINTS and \'STANDING\' algorithms have undergone external validation in emergency physician hands, showing good diagnostic accuracy. The objective of this consensus document is to provide scientific evidence supporting the clinical decisions made by physicians assessing adult patients with acute vertigo in the emergency department, particularly in cases without clear associated neurological signs. The document aims to offer a straightforward and multidisciplinary approach. At the same time, it tries to delineate benchmarks for the formulation of local diagnostic and therapeutic pathways, as well as provide a base for the development of training and research initiatives.
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  • 文章类型: English Abstract
    Vestibular rehabilitation therapy (VRT) is a highly effective treatment approach for addressing both peripheral and central vestibular disorders, offering the ability to significantly improve patients\' coordination and control across the vestibular, visual, and proprioceptive systems, all of which are crucial factors in maintaining balance. By promoting vestibular compensation, VRT has been shown to mitigate or even eliminate symptoms of dizziness, vertigo, and instability. With the rapid development of vestibular research, VRT has evolved into a more individualized and precise treatment approach based on evidence-based medicine. Its clinical effectiveness has been increasingly validated in numerous studies. With the involvement of multidisciplinary experts, this article aims to reach a consensus on the pre-treatment evaluation, formulation/implementation of treatment plans, and evidence-based treatment recommendations for common vestibular disorders, focusing on the prospects of vestibular rehabilitation. The goal is to further standardize and update VRT protocols for different vestibular disorders, providing comprehensive and context-specific guidance primarily tailored to the Chinese healthcare landscape, with a notable emphasis on its clinical applicability. Concurrently, it aspires to present new insights and serve as a valuable reference point for forthcoming high-quality clinical research on vestibular rehabilitation in China.
    前庭康复治疗(VRT)是治疗外周及中枢眩晕/前庭疾病的有效方法,可提高患者的前庭觉、视觉和本体觉对平衡的协调控制能力,促进前庭代偿,从而减轻或消除患者的头晕、眩晕和不稳症状。随着眩晕/前庭医学的快速发展,VRT已逐渐发展为基于循证医学的更为个体化和精准化的治疗手段,其临床疗效也在越来越多的研究中得到证实。在多学科专家的参与下,本文围绕前庭康复的治疗前评估、治疗方案的制定/实施、常见眩晕/前庭疾病基于循证医学的治疗建议达成共识,并对前庭康复的治疗前景进行展望,旨在进一步规范、补充及更新针对不同眩晕/前庭疾病的VRT方案,以期为临床提供符合我国国情、实操性强且更为详细的VRT指导,同时为国内未来前庭康复的高质量临床研究提供新的思路和参考。.
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  • 文章类型: Journal Article
    良性阵发性位置性眩晕(BPPV)是老年人头晕和跌倒的最常见原因之一。诊断和治疗BPPV可以减少跌倒,从而降低与跌倒相关的发病率和死亡率。最近的世界瀑布指南建议对有跌倒风险的老年人进行BPPV的正式评估,但前提是他们报告眩晕。然而,该建议忽略了以下数据:(i)许多患有BPPV的老年人将头晕视为模糊的不稳定(而不是眩晕),和(ii)其他人可能根本没有头晕症状。无眩晕的BPPV是由于前庭对自我运动的感知受损,称为“前庭失认症”。前庭失认症是在衰老中发现的,神经变性和创伤性脑损伤,并导致漏诊的BPPV显著增加。没有眩晕的BPPV患者通常最容易受到与该疾病相关的负面结果的影响。因此,我们建议简化世界瀑布指南:所有有客观或主观平衡问题的老年人(>60岁),不管有症状的投诉,应进行位置测试以检查BPPV。
    Benign paroxysmal positional vertigo (BPPV) is amongst the commonest causes of dizziness and falls in older adults. Diagnosing and treating BPPV can reduce falls, and thereby reduce fall-related morbidity and mortality. Recent World Falls Guidelines recommend formal assessment for BPPV in older adults at risk of falling, but only if they report vertigo. However, this recommendation ignores the data that (i) many older adults with BPPV experience dizziness as vague unsteadiness (rather than vertigo), and (ii) others may experience no symptoms of dizziness at all. BPPV without vertigo is due to an impaired vestibular perception of self-motion, termed \'vestibular agnosia\'. Vestibular agnosia is found in ageing, neurodegeneration and traumatic brain injury, and results in dramatically increased missed BPPV diagnoses. Patients with BPPV without vertigo are typically the most vulnerable for negative outcomes associated with this disorder. We thus recommend simplifying the World Falls Guidelines: all older adults (>60 years) with objective or subjective balance problems, irrespective of symptomatic complaint, should have positional testing to examine for BPPV.
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  • 文章类型: Review
    眩晕是一种常见的症状,可能有多种原因,可能需要从初级保健进行全面的诊断和治疗。提出了一种基于SEORL-PCF的Otoneurology委员会提出的分类的诊断算法,这有助于对不同类型的眩晕进行分类,并为患者提供从初级保健到其他专科的转诊标准。根据根本原因对可用的治疗方法进行审查,以进行适当的治疗管理。该文件有望成为治疗眩晕患者的专业人员的宝贵工具。该文件基于科学证据和各医学专业领域专家的经验;并寻求提高初级保健对急性眩晕的理解和临床方法。
    Vertigo is a common symptom that can have various causes and may require a comprehensive approach for its diagnosis and treatment from primary care. A diagnostic algorithm based on the classification proposed by the Otoneurology Commission of the SEORL-PCF is suggested, which facilitates the classification of the different types of vertigo and provides referral criteria for patients from primary care to other specialties. A review of the available treatments based on the underlying cause is conducted for appropriate therapeutic management. This document is expected to become a valuable tool for professionals treating patients with vertigo. The document is based on scientific evidence and on the experience of experts in the field from various medical specialties; and seeks to improve the understanding and clinical approach to acute vertigo from primary care.
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  • 文章类型: English Abstract
    Isolated otolith dysfunction(iOD) involves a group of unexplained vestibular syndromes that manifest clinically as a sense of translation, tilting or floating, and blurred vision with head movement, with normal semicircular canal function but abnormal otolith function on laboratory vestibular testing. As vestibular medicine has gained widespread popularity in recent years, increasing attention has also been paid to iOD and case reports, clinical studies and diagnostic criteria have been published. However, there is no consensus document to guide the diagnosis of this disease in China. In this context, the Special Committee on Vertigo of China Medical Education Association organized a group of domestic experts in vestibular medicine and formulated this diagnostic consensus after thorough discussion based on the latest evidence in China and abroad, in order to promote the best clinical practice for iOD.
    摘要: 孤立性耳石器功能障碍(isolated otolith dysfunction,iOD)是一组原因不明的前庭综合征,临床表现为平移、倾斜或漂浮感以及头部活动时的视敏度下降,前庭功能检查显示半规管功能正常但耳石器功能异常。随着前庭医学临床实践的广泛开展,对iOD的关注逐渐增加,国际上相关的病例报道、临床研究和诊断标准亦见诸报道。且在临床实践中,国内尚无共识文件指导该疾病的临床工作。在此背景下,中国医药教育协会眩晕专委会组织国内多名前庭医学专家,经过多次讨论,在参考借鉴国内外最新研究成果的基础上制定本诊断共识,以期规范开展iOD的临床诊疗工作。.
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  • 文章类型: Journal Article
    目的:尽管是临床实践中最常见的外周性眩晕类型之一,良性阵发性位置性眩晕(BPPV)仍未得到诊断和治疗,即使在富裕的医疗保健系统中。完全更新的临床实践指南的出版极大地促进了BPPV的诊断和治疗。这项研究评估了我们临床环境中指南的采用情况,并回顾了改善护理质量的进一步建议。
    方法:这项回顾性横断面调查包括在5年期间(2017-2021年)在该国最大的三级护理中心诊断为BPPV的1155名成年患者。前三年(2017-2020年)和919名患者的数据全部收集,其余236名患者(2020-2021年)仅部分是由于COVID-19大流行对转诊的干扰。
    结果:根据患者图表和我们的医疗保健数据库判断,医生对已发布的临床指南的熟悉程度和依从性总体上不能令人满意。在我们的样品中,粘附性从0变化到40.5%。只有20-30%的病例遵循了诊断和重新定位程序作为一线治疗的建议。
    结论:BPPV患者的护理质量有很大的改善机会。除了在初级卫生保健一级进行持续和系统的教育之外,医疗保健系统可能需要采取更先进的措施,以确保更好地遵守指南并随后降低医疗成本。
    OBJECTIVE: Despite being one of the most common types of the peripheral vertigo encountered in clinical practice, benign paroxysmal positional vertigo (BPPV) remains underdiagnosed and undertreated, even in affluent health care systems. The publication of fully updated clinical practice guidelines significantly facilitated the diagnosis and treatment of BPPV. This study evaluates the adoption of the guidelines in our clinical setting and reviews further recommendations for quality-of-care improvement.
    METHODS: This retrospective cross-sectional survey included a total of 1155 adult patients diagnosed with BPPV at the biggest tertiary care center in the country during a 5-year period (2017-2021). The data for the first three years (2017-2020) and 919 patients were collected in full, and for the remaining 236 patients (2020-2021) only partially due to the disturbance in referrals caused by COVID-19 pandemic.
    RESULTS: The familiarity with and adherence to the published clinical guidelines by physicians judged by patients\' charts and our health care database were overall unsatisfactory. The adherence varied from 0 to 40.5% in our sample. The recommendations for making the diagnosis and for repositioning procedure as first-line therapy were followed in only 20-30% of cases.
    CONCLUSIONS: There are large opportunities for improvement in quality of care of BPPV patients. Apart from constant and systematic education at the primary health care level, the health care system may need to adopt more advanced measures of ensuring better adherence to guidelines and subsequent reduction in medical costs.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    引言在以前的研究中已经注意到在临床医生中关于良性阵发性位置性眩晕(BPPV)的管理的临床实践中的差异。这种变化可能与对临床实践指南的不同依从性有关。目的评估临床医生对BPPV指南的依从性,并调查不同专业和资格之间依从性的差异。方法这是一项横断面研究,在6月至8月之间进行了基于小插图的调查,2020年。我们包括从事管理BPPV的临床医生,他们至少有一年的临床经验。我们排除了学生,和不参与BPPV患者管理的临床医生。要求参与者根据四个假设的患者小插曲做出管理选择。样本范围从第一个小插图的77名参与者到最后一个小插图的45名参与者。结果我们纳入了77名临床医生,大多数是耳鼻喉科医师(31.2%)。受访者平均遵守该指南的比例为63.3%。结果表明,耳鼻喉科医师的依从性高于不同专业的临床医师(p=0.006,d=0.72)。此外,具有研究生学位的临床医生比仅具有学士学位的临床医生更有可能坚持该指南(p=0.014,d=0.58),并且了解该指南的参与者更有可能坚持该指南(p<0.001,d=1.05).最后,回归分析显示,依从性受研究生学位和指南意识的影响。结论耳鼻喉科医师比其他专科医师更有可能遵守该指南。在所有专业中,较高的依从性与指南意识和研究生学位相关.
    Introduction  Variations in clinical practice regarding the management of benign paroxysmal positional vertigo (BPPV) among clinicians have been noted in previous studies. Such variations might be related to the different adherence to clinical practice guidelines. Objective  To evaluate clinicians\' adherence to BPPV guidelines and investigate the variations in the adherence between different specialties and qualifications. Methods  This is a cross-sectional study with a vignettes-based survey conducted between June and August, 2020. We included clinicians engaged in managing BPPV that had at least one year of clinical experience. We excluded students, and clinicians who were not involved in the management of individuals with BPPV. Participants were asked to make their management choices based on four hypothetical patient vignettes. The sample ranged from 77 participants for the first vignette to 45 participants for the last vignette. Results  We included 77 clinicians in the study, with the majority being Otolaryngologists (31.2%). The respondents\' mean adherence to the guideline was of 63.3%. Result showed that Otolaryngologists\' adherence was higher than that of clinicians from different specialties ( p  = 0.006, d  = 0.72). Furthermore, clinicians with a postgraduate degree were more likely to adhere than those with a bachelor\'s degree only ( p  = 0.014, d  = 0.58) and participants who were aware of the guideline were more likely to adhere to it ( p  < 0.001, d  = 1.05). Lastly, regression analysis exhibited that adherence was affected by postgraduate degree and guideline awareness. Conclusion  Otolaryngologists were more likely to adhere to the guideline than other specialties. Among all specialties, higher adherence was associated with guideline awareness and postgraduate degrees.
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  • 文章类型: Review
    这项审查的目的是评估眩晕和头晕管理指南的方法学质量,并比较其建议,特别关注神经成像。
    MEDLINE,EMBASE,国家准则信息交换所,和国家健康与临床卓越数据库研究所。
    2022年3月,进行了系统搜索,以寻找眩晕和头晕管理的实践指南。指南质量的评估由四位作者使用AGREEII工具独立进行。我们从结果中排除了那些不主要关注眩晕和头晕的指南,例如国家/国际准则,其中仅简要提及眩晕和头晕。
    我们的文献检索策略确定了161项研究,并选择了18条准则进行评估。只有五个准则在总体结果中达到了接受水平(至少60%),其中三人得分最高(至少80%)。最高分出现在第6域“编辑独立性”中,“域1”范围和目的,\"和域4\"演示的清晰度\"(中值=66%,62%,61%,分别)。其余领域的质量水平较低:领域2“利益相关者的参与,“域3”发展的严谨,“和领域5”适用性的中值为27%,27%,22%,分别。这些指南的质量很低,由于多学科团队在编写指南建议方面的参与度较低。
    考虑到所有准则,只有三个人的总分“高”,而其中18人中有13人(72%)被评为“低”质量。未来的指南可能会考虑到这一点,以提高临床适用性。
    The aim of this review is to assess the methodological quality of guidelines for the management of vertigo and dizziness and to compare their recommendations, with specific focus on neuroimaging.
    MEDLINE, EMBASE, National Guideline Clearinghouse, and National Institute for Health and Clinical Excellence database.
    In March 2022, a systematic search was performed to find practice guidelines of management of vertigo and dizziness. The evaluation of guidelines quality was performed independently by four authors using the AGREE II tool. We excluded from the results those guidelines that were not primarily focused on vertigo and dizziness, such as national/international guidelines in which vertigo and dizziness were only briefly mentioned.
    Our strategy of literature search identified 161 studies, and 18 guidelines were selected for the appraisal. Only five guidelines reached the acceptance level in the overall result (at least 60%), with three of them reaching the highest scores (at least 80%). The highest scores were found in Domain 6 \"Editorial Independence,\" Domain 1 \"Scope and purpose,\" and Domain 4 \"Clarity of presentation\" (median value = 66%, 62%, and 61%, respectively). The remaining domains showed a low level of quality: Domain 2 \"Stakeholder Involvement,\" Domain 3 \"Rigor of development,\" and Domain 5 \"Applicability\" had median values of 27%, 27%, and 22%, respectively. The quality of these guidelines was very low, because of low involvement of multidisciplinary teams in writing guidelines recommendations.
    Considering all guidelines, only three had a \"high\" overall score, whereas 13 of 18 (72%) of them were rated as of \"low\" quality. Future guidelines might take this into account to improve clinical applicability.
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  • 文章类型: Journal Article
    背景:短期糖皮质激素是治疗前庭神经炎(VN)专家考虑的治疗策略之一。我们进行了一项综述(系统评价的系统评价),以总结使用皮质类固醇治疗VN的证据。
    方法:我们纳入了随机对照试验(RCT)和观察性研究的系统评价,这些研究评估了糖皮质激素与安慰剂或常规治疗对成年急性VN患者的影响。标题,摘要,全文一式两份。使用AMeaSurement工具评估系统评论(AMSTAR-2)工具评估评论的质量。建议的分级,评估,开发和评估(GRADE)评估用于评估证据的确定性。未进行荟萃分析。
    结果:来自149个标题,选择了五项系统评价进行质量评估,两篇综述的方法学质量较高,被纳入。这两项综述包括12项个体研究和660例VN患者。在两项RCT的荟萃分析中,包括总共50名患者,使用皮质类固醇(与安慰剂相比)与更高的完全热量恢复相关(风险比2.81,95%置信区间[CI]1.32~6.00,低确定性).非常不确定这是否转化为临床改善,如患者报告的眩晕或患者报告的头晕残疾等结果的不精确效果估计所示。头晕障碍评分的结果有一个广泛的CI(一项研究,30名患者,皮质类固醇组的20.9分与安慰剂15.8分,平均差异+5.1,95%CI-8.09至+18.29,非常低的确定性)。据报道,接受皮质类固醇治疗的患者的轻微不良反应发生率较高,但是这个证据的确定性很低。
    结论:支持在急诊科使用皮质类固醇治疗VN的证据有限。
    A short course of corticosteroids is among the management strategies considered by specialists for the treatment of vestibular neuritis (VN). We conducted an umbrella review (systematic review of systematic reviews) to summarize the evidence of corticosteroids use for the treatment of VN.
    We included systematic reviews of randomized controlled trials (RCTs) and observational studies that evaluated the effects of corticosteroids compared to placebo or usual care in adult patients with acute VN. Titles, abstracts, and full texts were screened in duplicate. The quality of reviews was assessed with the A MeaSurement Tool to Assess systematic Reviews (AMSTAR-2) tool. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) assessment was used to rate certainty of evidence. No meta-analysis was performed.
    From 149 titles, five systematic reviews were selected for quality assessment, and two reviews were of higher methodological quality and were included. These two reviews included 12 individual studies and 660 patients with VN. In a meta-analysis of two RCTs including a total of 50 patients, the use of corticosteroids (compared to placebo) was associated with higher complete caloric recovery (risk ratio 2.81, 95% confidence interval [CI] 1.32 to 6.00, low certainty). It is very uncertain whether this translates into clinical improvement as shown by the imprecise effect estimates for outcomes such as patient-reported vertigo or patient-reported dizziness disability. There was a wide CI for the outcome of dizziness handicap score (one study, 30 patients, 20.9 points in corticosteroids group vs. 15.8 points in placebo, mean difference +5.1, 95% CI -8.09 to +18.29, very low certainty). Higher rates of minor adverse effects for those receiving corticosteroids were reported, but the certainty in this evidence was very low.
    There is limited evidence to support the use of corticosteroids for the treatment of VN in the emergency department.
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