socioeconomic factors

社会经济因素
  • 文章类型: Journal Article
    背景:有组织的乳腺癌筛查(BCS)计划是50-69岁女性预防德国第六大死亡原因的有效措施。尽管国家筛查计划的实施始于2005年,但参与率尚未达到欧盟标准。目前尚不清楚哪些社会人口统计学因素以及如何与BCS出勤率相关。这项范围审查旨在确定在德国实施有组织的筛查计划后,50-69岁女性在BCS出勤率方面的社会人口统计学不平等。
    方法:遵循PRISMA指南,我们搜索了科学网,Scopus,MEDLINE,PsycINFO,跟随PCC的CINAHL(人口,概念和上下文)标准。我们纳入了定量研究设计的主要研究,并审查了50-69岁女性的BCS出勤率,并收集了2005年以来德国的数据。制定了收获图,描绘了不同的社会人口统计学不平等以及最近两年或更少的BCS出勤率和终身BCS出勤率的影响大小方向。
    结果:我们筛选了476篇标题和摘要以及33篇全文。总的来说,分析了27条记录,14是国家报告,和13篇同行评议的文章。在收获地块中确定并总结了八个社会人口统计学变量:年龄,教育,收入,迁移状态,区的类型,就业状况,合伙同居和健康保险。生活在农村地区且缺乏私人保险的低收入和移民背景的老年妇女对BCS邀请的反应更积极。然而,从一生的角度来看,这些协会只适用于移民背景,在收入和城市居住权方面被逆转,并辅以伴侣同居。最后,生活在前东德萨克森州的妇女,梅克伦堡-西波美拉尼亚,萨克森-安哈尔特,和图林根,以及前西德下萨克森州,在过去两年中,BCS出勤率较高。
    结论:需要高质量的研究来确定在德国没有参加BCS的风险较高的女性,以解决现有研究的高异质性,特别是因为整体出勤率仍然低于欧洲标准。
    背景:https://osf.io/x79tq/。
    BACKGROUND: Organized breast cancer screening (BCS) programs are effective measures among women aged 50-69 for preventing the sixth cause of death in Germany. Although the implementation of the national screening program started in 2005, participation rates have not yet reached EU standards. It is unclear which and how sociodemographic factors are related to BCS attendance. This scoping review aims to identify sociodemographic inequalities in BCS attendance among 50-69-year-old women following the implementation of the Organized Screening Program in Germany.
    METHODS: Following PRISMA guidelines, we searched the Web of Science, Scopus, MEDLINE, PsycINFO, and CINAHL following the PCC (Population, Concept and Context) criteria. We included primary studies with a quantitative study design and reviews examining BCS attendance among women aged 50-69 with data from 2005 onwards in Germany. Harvest plots depicting effect size direction for the different identified sociodemographic inequalities and last two years or less BCS attendance and lifetime BCS attendance were developed.
    RESULTS: We screened 476 titles and abstracts and 33 full texts. In total, 27 records were analysed, 14 were national reports, and 13 peer-reviewed articles. Eight sociodemographic variables were identified and summarised in harvest plots: age, education, income, migration status, type of district, employment status, partnership cohabitation and health insurance. Older women with lower incomes and migration backgrounds who live in rural areas and lack private insurance respond more favourably to BCS invitations. However, from a lifetime perspective, these associations only hold for migration background, are reversed for income and urban residency, and are complemented by partner cohabitation. Finally, women living in the former East German states of Saxony, Mecklenburg-Western Pomerania, Saxony-Anhalt, and Thuringia, as well as in the former West German state of Lower Saxony, showed higher BCS attendance rates in the last two years.
    CONCLUSIONS: High-quality research is needed to identify women at higher risk of not attending BCS in Germany to address the existing research\'s high heterogeneity, particularly since the overall attendance rate still falls below European standards.
    BACKGROUND: https://osf.io/x79tq/ .
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  • 文章类型: Journal Article
    The objective of this study was to identify indicators of social inequalities associated with mortality from neoplasms in the Brazilian adult population. A scoping review method was used, establishing the guiding question: What is the effect of social inequalities on mortality from neoplasms in the Brazilian adult population? A total of 567 papers were identified, 22 of which were considered eligible. A variety of indicators were identified, such as the Human Development Index and the Gini Index, which primarily assessed differences in income, schooling, human development and vulnerability. A single pattern of association between the indicators and the different neoplasms was not established, nor was a single indicator capable of explaining the effect of social inequality at all levels of territorial area and by deaths from all types of neoplasms identified. It is known that mortality is influenced by social inequalities and that the study of indicators provides an opportunity to define which best explains deaths. This review highlights important gaps regarding the use of non-modifiable social indicators, analysis of small geographical areas, and limited use of multidimensional indicators.
    O objetivo deste estudo foi identificar indicadores de desigualdades sociais associados à mortalidade por neoplasias na população adulta brasileira. Utilizou-se como método a revisão de escopo, estabelecendo-se a pergunta norteadora: qual o efeito das desigualdades sociais na mortalidade por neoplasias na população adulta brasileira? Foram identificados 567 trabalhos, sendo 22 considerados elegíveis. Identificou-se uma diversidade de indicadores, como o Índice de Desenvolvimento Humano e o Índice de Gini, entre outros, que avaliaram primordialmente diferenças de renda, escolarização, desenvolvimento humano e vulnerabilidade. Não foi estabelecido um único padrão de associação entre os indicadores e as diferentes neoplasias, assim como não se identificou um indicador único capaz de explicar o efeito da desigualdade social em todos os níveis de área e por óbitos por todos os tipos de neoplasias, mas identificou-se que a mortalidade é influenciada pelas desigualdades sociais e que o estudo dos indicadores proporciona definir qual melhor explica os óbitos. Essa revisão destaca importantes lacunas referentes ao uso de indicadores sociais não modificáveis, à análise de pequenas áreas e ao uso limitado de indicadores multidimensionais.
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  • 文章类型: Journal Article
    背景:大多数老年人希望随着年龄的增长留在家中和社区。尽管有这种普遍的偏好,在健康结果和获得医疗保健和社会支持方面的差异可能会造成年龄能力的不平等。我们的目标是使用交叉透镜综合老年人中老龄化社会不平等的证据,并评估用于定义和衡量不平等的方法。
    方法:我们进行了一项混合研究系统综述。我们搜索了MEDLINE,EMBASE,PsycINFO,CINAHL和AgeLine提供定量或定性文献,研究了经济合作与发展组织(OECD)成员国中65岁及以上的成年人在老龄化方面的社会不平等。纳入研究的结果是在PROGRESS-Plus框架的指导下使用定性内容分析进行综合。
    结果:在4874条确定的记录中,共纳入55项研究。农村居民,种族/族裔少数,移民和那些具有较高社会经济地位和更多社会资源的人更有可能在当地老化。女性和受教育程度较高的女性似乎不太可能在原地变老。社会经济地位的影响,教育和社会资源因性别和种族/民族而异,表明跨社会维度的交叉效应。
    结论:社会维度影响经合组织环境中的年龄能力,可能是由于整个生命周期的健康不平等,获得医疗保健和支持服务的差距,以及对老化的不同偏好。我们的结果可以为制定政策和方案提供信息,以公平地支持不同人群的老龄化。
    BACKGROUND: Most older adults wish to remain in their homes and communities as they age. Despite this widespread preference, disparities in health outcomes and access to healthcare and social support may create inequities in the ability to age in place. Our objectives were to synthesise evidence of social inequity in ageing in place among older adults using an intersectional lens and to evaluate the methods used to define and measure inequities.
    METHODS: We conducted a mixed studies systematic review. We searched MEDLINE, EMBASE, PsycINFO, CINAHL and AgeLine for quantitative or qualitative literature that examined social inequities in ageing in place among adults aged 65 and older in Organisation for Economic Co-operation and Development (OECD) member countries. Results of included studies were synthesised using qualitative content analysis guided by the PROGRESS-Plus framework.
    RESULTS: Of 4874 identified records, 55 studies were included. Rural residents, racial/ethnic minorities, immigrants and those with higher socioeconomic position and greater social resources are more likely to age in place. Women and those with higher educational attainment appear less likely to age in place. The influence of socioeconomic position, education and social resources differs by gender and race/ethnicity, indicating intersectional effects across social dimensions.
    CONCLUSIONS: Social dimensions influence the ability to age in place in OECD settings, likely due to health inequalities across the lifespan, disparities in access to healthcare and support services, and different preferences regarding ageing in place. Our results can inform the development of policies and programmes to equitably support ageing in place in diverse populations.
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  • 文章类型: Systematic Review
    人们已经认识到,与艾滋病毒相关的污名阻碍了检测工作,治疗,和预防。在这次系统审查中,我们的目的是总结艾滋病毒相关的污名和年龄之间的关联的现有发现,社会支持,教育状况,抑郁症,就业状况,财富指数,性别,residence,关于艾滋病毒的知识,婚姻状况,自诊断以来的持续时间,和披露状况使用了大量的研究。
    电子数据库,包括Scopus,Medline/PubMed,WebofSciences(WOS),科克伦图书馆,谷歌学者,和开放研究数据集挑战进行了系统搜索,直到2023年4月15日。我们包括了各种艾滋病毒污名研究,不管语言,发布日期,或地理位置。40项研究符合纳入标准,共有171627名患者。使用混合效应模型来汇集估计值和评估发表偏差,以及进行敏感性分析。
    年龄等因素,社会支持,高等教育,更高的社会经济地位,良好的艾滋病毒知识,和更长的艾滋病毒感染年限显著降低了与艾滋病毒相关的耻辱的可能性。相反,抑郁等因素,居住在农村地区,女性受访者,和未披露HIV状况与HIV相关污名的高风险显著相关.
    为了对抗与艾滋病毒相关的系统性耻辱,通过提高社区一级的艾滋病毒认识,发展健康和全面的社会方法至关重要。除了激进主义,地方经济发展对于建立具有强大社会结构的繁荣社区也至关重要。
    UNASSIGNED: It has been recognized that HIV-related stigma hinders efforts in testing, treatment, and prevention. In this systematic review, we aimed to summarize available findings on the association between HIV-related stigma and age, social support, educational status, depression, employment status, wealth index, gender, residence, knowledge about HIV, marital status, duration since diagnosis, and disclosure status using a large number of studies.
    UNASSIGNED: Electronic databases including Scopus, Medline/PubMed, Web of Sciences (WOS), Cochrane Library, Google Scholar, and Open Research Dataset Challenge were systematically searched until 15 April 2023. We included all kinds of HIV-stigma studies, regardless of language, publishing date, or geographic location. The inclusion criteria were met by 40 studies, with a total of 171,627 patients. A mixed-effect model was used to pool estimates and evaluate publication bias, as well as to conduct sensitivity analysis.
    UNASSIGNED: Factors such as older age, social support, greater education, higher socioeconomic status, good knowledge of HIV, and longer years of living with HIV significantly lowered the likelihood of HIV-related stigma. Contrarily, factors such as depression, residing in rural areas, female respondents, and non-disclosure of HIV status were significantly associated with a high risk of HIV-related stigma.
    UNASSIGNED: To combat systemic HIV-associated stigma, it is crucial to develop wholesome and comprehensive social methods by raising community-level HIV awareness. In addition to activism, local economic development is also crucial for creating thriving communities with a strong social fabric.
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  • 文章类型: Journal Article
    背景:早育在非洲非常普遍。尽管早育对年轻人造成有害后果,旨在改善非洲大陆年轻父母的健康和社会经济福祉的干预措施的文件有限。在这次系统审查中,我们将绘制并提供旨在改善非洲年轻父母的健康和社会经济福祉的干预措施的关键综合,为未来的政策和方案决策提供信息。
    方法:系统评价将遵循系统评价和荟萃分析(PRISMA)指南的首选报告项目。我们将对发表在六个数据库中的同行评审文章进行电子搜索:PubMed,科学直接,AJOL,JSTOR,ERIC和谷歌学者。我们还将通过Google搜索和组织网站搜索灰色文献,以扩大检索到的干预措施的数量。如果(1)研究参与者是10-24岁的年轻母亲和父亲,(2)文章报告了针对非洲或非洲个别国家的年轻母亲和父亲的干预措施,(3)文章以英文或法文发表,(4)文章报告了健康和社会经济福祉结果,(5)文章发表于2000年1月1日至2023年12月31日。我们将从符合纳入标准的文章中提取相关信息,并使用定量和定性方法综合数据。两名审稿人将独立筛选文章以供收录,从纳入的文章中提取数据,并评估研究的方法学质量。
    背景:系统评价不需要伦理批准,因为我们正在合成公开的出版物。这项系统评价的结果将发表在同行评审的期刊上,并在会议和大会上进一步传播,重点关注年轻父母的健康和社会经济福祉。
    CRD42023464828。
    BACKGROUND: Early childbearing is highly prevalent in Africa. Despite the harmful consequences of early childbearing on young people, there is limited documentation of interventions that aim to improve the health and socioeconomic well-being of young parents on the continent. In this systematic review, we will map and provide a critical synthesis of interventions that aim to improve the health and socioeconomic well-being of young parents in Africa to inform future policy and programmatic decision-making.
    METHODS: The systematic review will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We will conduct an electronic search of peer-reviewed articles published in six databases: PubMed, Science Direct, AJOL, JSTOR, ERIC and Google Scholar. We will also search for grey literature through Google search and organisations\' websites to broaden the number of interventions retrieved. Articles will be included if (1) the study participants are young mothers and fathers aged 10-24 years, (2) the article reports on interventions targeting young mothers and fathers in Africa or individual countries in Africa, (3) the article is published in English or French, (4) the article reports on health and socioeconomic well-being outcomes and (5) the article was published between 1 January 2000 and 31 December 2023. We will extract relevant information from articles that meet the inclusion criteria and synthesise data using both quantitative and qualitative approaches. Two reviewers will independently screen articles for inclusion, extract data from included articles and assess the methodological quality of studies.
    BACKGROUND: Ethical approval is not required for the systematic review since we are synthesising publicly available publications. Findings from this systematic review will be published in a peer-reviewed journal and further disseminated in conferences and convenings focusing on the health and socioeconomic well-being of young parents.
    UNASSIGNED: CRD42023464828.
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  • 文章类型: Journal Article
    目的:确定现有文献中根据创伤性脑损伤幸存者的社会经济地位(伤前或伤后)分析医疗费用的文章。次要目的是描述成本和社会经济特征的类型,并确定社会经济特征是否会影响创伤性脑损伤的风险,或者创伤的后果是否会改变受伤后的生活条件。
    方法:此范围审查遵循Arksey和O\'Malley提出的方法。在5个数据库中进行文献检索。
    结果:包括22篇文章,1988年至2023年出版。只有2篇文章(9%)遵循了医疗保健计划的经济评估指南,而2篇文章(9%)则“完全”评估了社会经济地位,并具有3个主要的社会经济特征指标(即,教育,收入,和职业)。在创伤性脑损伤中,成本和社会经济特征之间的关系可能在两个方面有所不同:社会经济劣势主要与更高的医疗保健成本有关。医疗费用降低了幸存者的生活条件。
    结论:这项工作强调需要对社会经济特征与创伤相关成本之间的关系进行详细和方法学上的合理评估。对创伤性脑损伤的护理途径进行建模将有可能识别TBI后康复不良或恶化风险的人群。并开发特定的护理途径。目的是建立更合适的,有效,和公平的护理计划。
    OBJECTIVE: To identify the articles in the existing literature that analyse healthcare costs according to the socioeconomic position (pre- or post-injury) for traumatic brain injury survivors. Secondary aims were to describe the types of costs and socioeconomic characteristics and to determine whether socioeconomic characteristics affect the risk of traumatic brain injury or whether the consequences of trauma alter living conditions post-injury.
    METHODS: This scoping review followed the methods proposed by Arksey and O\'Malley. The literature search was performed in 5 databases.
    RESULTS: Twenty-two articles were included, published between 1988 and 2023. Only 2 articles (9%) followed the guidelines for economic evaluation of healthcare programmes and 2 articles (9%) evaluated socioeconomic position \"completely\" with 3 main individual measures of socioeconomic characteristics (i.e., education, income, and occupation). The relationship between costs and socioeconomic characteristics could vary in 2 ways in traumatic brain injury: socioeconomic disadvantage was mostly associated with higher healthcare costs, and the cost of healthcare reduced the survivors\' living conditions.
    CONCLUSIONS: This work highlights the need for a detailed and methodologically sound assessment of the relationship between socioeconomic characteristics and the costs associated with trauma. Modelling the care pathways of traumatic brain injury would make it possible to identify populations at risk of poor recovery or deterioration following a TBI, and to develop specific care pathways. The aim is to build more appropriate, effective, and equitable care programmes.
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  • 文章类型: Journal Article
    社会健康驱动因素(SDOH)在发生中的重要性,检测,治疗,心房颤动(AF)的转归越来越受到关注。解决SDOH因素可能提示预防AF及其并发症的机会。我们的目标是进行结构化的叙事回顾,并总结当前关于种族和民族之间关联的知识,SDOH,包括农村与城市居住,教育,收入,和邻里,和房颤的风险,其管理,和并发症。我们确定了PubMed中的537个参考文献和Embase中的473个参考文献。删除重复项后,我们筛选了975篇参考文献的摘要,导致113个参考文献被审查为合格。随后,排除了34个参考文献,留下了79个参考文献供审查。房颤发病率和患病率的社会梯度证据相互矛盾。然而,我们发现了大量证据表明房颤检测中的社会不平等,获得治疗,以及医疗保健利用等结果,出血,心力衰竭,中风,痴呆症,工作残疾,和死亡。据报道,各种医疗保健系统存在不平等现象,构成影响几大洲的全球问题,尽管缺乏来自非洲和南美的数据。鉴于房颤检测中记录的社会不平等现象,管理,和结果,迫切需要医疗保健系统,政策制定者,和社会来确定和实施有效的干预措施,可以减少不平等和改善个人房颤的结果。
    The importance of social drivers of health (SDOH) in the occurrence, detection, treatment, and outcome of atrial fibrillation (AF) has attracted increasing attention. Addressing SDOH factors may suggest opportunities to prevent AF and its complications. We aimed to conduct a structured narrative review and summarize current knowledge on the association between race and ethnicity, SDOH, including rural vs. urban habitation, education, income, and neighbourhood, and the risk of AF, its management, and complications. We identified 537 references in PubMed and 473 references in Embase. After removal of duplicates, we screened the abstracts of 975 references, resulting in 113 references that were examined for eligibility. Subsequently, 34 references were excluded leaving 79 references for the review. Evidence of a social gradient in AF incidence and prevelance were conflicting. However, we found substantial evidence indicating social inequities in the detection of AF, access to treatment, and outcomes such as healthcare utilization, bleeding, heart failure, stroke, dementia, work disability, and death. Inequities are reported across various health care systems and constitute a global problem affecting several continents, although data from Africa and South America are lacking. Given the documented social inequities in AF detection, management, and outcomes, there is an urgent need for healthcare systems, policymakers, and society to identify and implement effective interventions that can reduce inequities and improve outcomes in individuals with AF.
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  • 文章类型: Journal Article
    背景:越来越多的文献记录了COVID-19大流行的次要影响如何加剧了社会中已经存在的社会经济脆弱性,特别是跨社会类别,如性别,种族,类,和社会经济地位。这些影响表明,大流行应对政策如何作为健康的结构性决定因素,不仅影响直接健康结果,而且影响中介结果,例如获得教育或收入。
    方法:这篇综述旨在从公平的角度分析加拿大大流行应对政策的研究范围,为了确定共同的主题,recommendations,和差距。
    结果:对14项研究进行了主题分析,大多数是定性政策文件分析,应用关键框架,并专注于对选定优先人群的影响。对经济和劳工政策的分析表明,没有考虑优先人群的具体需求,那些从事不稳定的人,非正式,和基本劳动。对社会政策的分析说明了学校和服务关闭的广泛影响,特别是妇女和儿童。此外,这些政策缺乏对疫情期间边缘化人群的考虑,包括老年人和他们的照顾者,以及缺乏对土著社区多样性的考虑。本次审查中提出的建议呼吁制定应对政策,解决持续存在的社会和经济不平等,针对优先人群的需求制定大流行应对政策,并在政策制定过程中进行更有意义的协商。
    结论:数量有限的研究表明,承认政策是健康不平等的结构性决定因素的研究仍有很大的余地。包括采取交叉方法的研究。
    BACKGROUND: A growing literature has documented how the secondary effects of the COVID-19 pandemic have compounded socioeconomic vulnerabilities already present in society, particularly across social categories such as gender, race, class, and socioeconomic status. Such effects demonstrate how pandemic response policies act as structural determinants of health to influence not only direct health outcomes but also intermediary outcomes, such as access to education or income.
    METHODS: This review aims to scope research that analyzes pandemic response policies in Canada from an equity perspective, to identify common themes, recommendations, and gaps.
    RESULTS: Fourteen studies were thematically analyzed, the majority being qualitative policy document analysis, applying critical frameworks and focused on effects on select priority populations. Analysis of economic and labour policies indicates a lack of consideration for the specific needs of priority populations, and those engaged in precarious, informal, and essential labour. Analysis of social policies illustrate the wide-ranging effects of school and service closures, particularly on women and children. Furthermore, these policies lacked consideration of populations marginalized during the pandemic, include older adults and their caregivers, as well as lack of consideration of the diversity of Indigenous communities. Recommendations proposed in this review call for developing policy responses that address persistent social and economic inequities, pandemic response policies tailored to the needs of priority populations and more meaningful consultation during policy development.
    CONCLUSIONS: The limited number of studies suggests there is still much scope for research recognizing policies as structural determinants of health inequities, including research which takes an intersectional approach.
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  • 文章类型: Journal Article
    背景:潜在不适当的处方(PIP)是指具有较高不良结局风险的药物处方,如药物相互作用,falls,和认知障碍。PIP在老年人中尤其令人关注,并与发病率增加有关,死亡率,和医疗费用。社会经济匮乏已被确定为PIP的潜在风险因素。然而,这种关系的程度尚不清楚。这篇综述旨在综合当前有关老年人PIP与社会经济地位(SES)之间关联的文献。
    方法:使用Medline数据库进行文献检索,Embase和CINAHL。开发了一种搜索策略来捕获研究三个关键概念的论文:PIP,社会经济匮乏和老年人/老年人口。在2000年1月1日至2022年12月31日之间发表的同行评审定量研究有资格纳入。
    结果:来自3,966个命中的20篇文章符合纳入标准。纳入研究的样本量从668到1650万人不等,其中大部分来自欧洲(n=8)和北美(n=8)。大多数将老年患者定义为65岁或以上(n=12),并使用收入(n=7)或补贴资格(n=5)来评估SES。总之,12项研究报告了社会经济剥夺与经历PIP的可能性增加之间的统计学显著关联。其中一些报告称,在调整了服用药物的数量后,有一些关联,或者多重用药的存在。关联的根本原因尚不清楚,尽管一项研究发现,剥夺和较高的PIP患病率之间的关联不能用获得医疗机构或从业人员的机会较差来解释.
    结论:研究结果表明,老年人的SES与他们暴露于PIP的可能性之间存在某种关联。SES似乎是独立和协同作用以影响老年人经历PIP的可能性的几个因素之一。这篇评论强调,在进行药物审查时,优先考虑生活在社会经济贫困环境中的老年人可能是一种有效的策略。
    BACKGROUND: Potentially inappropriate prescribing (PIP) refers to the prescription of medications that carry a higher risk of adverse outcomes, such as drug interactions, falls, and cognitive impairment. PIP is of particular concern in older adults, and is associated with increased morbidity, mortality, and healthcare costs. Socioeconomic deprivation has been identified as a potential risk factor for PIP. However, the extent of this relationship remains unclear. This review aimed to synthesize the current literature on the association between PIP and socioeconomic status (SES) in older adults.
    METHODS: A literature search was conducted using the databases Medline, Embase and CINAHL. A search strategy was developed to capture papers examining three key concepts: PIP, socioeconomic deprivation and older/elderly populations. Peer-reviewed quantitative research published between 1/1/2000 and 31/12/2022 was eligible for inclusion.
    RESULTS: Twenty articles from 3,966 hits met the inclusion criteria. The sample size of included studies ranged from 668 to 16.5million individuals, with the majority from Europe (n = 8) and North America (n = 8). Most defined older patients as being 65 or over (n = 12) and used income (n = 7) or subsidy eligibility (n = 5) to assess SES. In all, twelve studies reported a statistically significant association between socioeconomic deprivation and an increased likelihood of experiencing PIP. Several of these reported some association after adjusting for number of drugs taken, or the presence of polypharmacy. The underlying reasons for the association are unclear, although one study found that the association between deprivation and higher PIP prevalence could not be explained by poorer access to healthcare facilities or practitioners.
    CONCLUSIONS: The findings suggest some association between an older person\'s SES and their likelihood of being exposed to PIP. SES appears to be one of several factors that act independently and in concert to influence an older person\'s likelihood of experiencing PIP. This review highlights that prioritising older people living in socioeconomically-deprived circumstances may be an efficient strategy when carrying out medication reviews.
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  • 文章类型: Journal Article
    背景:癫痫发病率及其不良后果的社会经济不平等在国际上有记载,然而,各国之间的不平等程度和影响协会的因素可能有所不同。英国对癫痫的公共卫生反应,在不扩大不平等的情况下预防癫痫,是必需的。然而,关于英国癫痫不平等的数据尚未在综述中综合,潜在的决定因素未知.
    方法:在本系统综述和荟萃分析中,我们搜索了六个书目数据库(MEDLINE,Embase,PsycINFO,CINAHL,WebofScience,和Scopus)和1980年1月1日至2024年2月21日之间发表的灰色文献,以根据社会经济因素(个体水平或地区水平)确定英国报告癫痫发病率或癫痫相关不良结局的研究。我们纳入了纵向队列研究,使用常规收集的医疗保健数据的研究,横断面研究,以及匹配的队列研究和排除的会议摘要,以及在审查和荟萃分析中未报告实证结果的研究。多个审阅者(KJB,EC,SER,WOP,和RHT)独立筛选的研究,KJB从所包含的研究中提取数据,并由第二审阅者(SM或EC)检查数据提取。我们使用关键评估技能计划检查表来评估质量。我们使用随机效应荟萃分析来汇总事件发生率比率(IRRs),并对不良结果进行了叙述。本研究在PROPSPERO(CRD42023394143)上注册。
    结果:我们从数据库搜索中确定了2471项独特的研究。我们纳入了26项研究,根据社会经济因素,其中10例报告了癫痫的发病率,16例报告了癫痫相关的不良结局.错误分类,参与,和解释性偏差被确定为研究质量限制。荟萃分析显示,社会经济剥夺与癫痫发病率之间存在关联,与低剥夺组相比,高剥夺组(IRR1·34[95%CI1·16-1·56];I2=85%)和中剥夺组(IRR1·23[95%CI1·08-1·39];I2=63%)发生癫痫的风险更高.这种关联在仅包括儿童的研究中仍然存在(高与低:IRR1·36[95%CI1·19-1·57];I2=0%)。只有两项研究检查了影响癫痫发病率的因素。关于英国不利结果不平等的证据有限。
    结论:在英国,癫痫发病率的社会经济不平等是显而易见的。制定以证据为基础的癫痫公共卫生应对措施,需要进一步的研究来了解受影响的人群,决定关联的因素,以及不利结果不平等的程度。
    背景:英国癫痫研究所。
    BACKGROUND: Socioeconomic inequalities in epilepsy incidence and its adverse outcomes are documented internationally, yet the extent of inequalities and factors influencing the association can differ between countries. A UK public health response to epilepsy, which prevents epilepsy without widening inequalities, is required. However, the data on UK epilepsy inequalities have not been synthesised in a review and the underlying determinants are unknown.
    METHODS: In this systematic review and meta-analysis, we searched six bibliographic databases (MEDLINE, Embase, PsycINFO, CINAHL, Web of Science, and Scopus) and grey literature published between Jan 1, 1980, and Feb 21, 2024, to identify UK studies reporting epilepsy incidence or epilepsy-related adverse outcomes by socioeconomic factors (individual level or area level). We included longitudinal cohort studies, studies using routinely collected health-care data, cross-sectional studies, and matched cohort studies and excluded conference abstracts and studies not reporting empirical results in the review and meta-analysis. Multiple reviewers (KJB, EC, SER, WOP, and RHT) independently screened studies, KJB extracted data from included studies and a second reviewer (SM or EC) checked data extraction. We used Critical Appraisal Skills Programme checklists to assess quality. We used random-effects meta-analysis to pool incident rate ratios (IRRs) and synthesised results on adverse outcomes narratively. This study was registered on PROPSPERO (CRD42023394143).
    RESULTS: We identified 2471 unique studies from database searches. We included 26 studies, ten of which reported epilepsy incidence and 16 reported epilepsy-related adverse outcomes according to socioeconomic factors. Misclassification, participation, and interpretive biases were identified as study quality limitations. Meta-analyses showed an association between socioeconomic deprivation and epilepsy incidence, with greater risks of epilepsy incidence in groups of high-deprivation (IRR 1·34 [95% CI 1·16-1·56]; I2=85%) and medium-deprivation (IRR 1·23 [95% CI 1·08-1·39]; I2=63%) compared with low-deprivation groups. This association persisted in the studies that only included children (high vs low: IRR 1·36 [95% CI 1·19-1·57]; I2=0%). Only two studies examined factors influencing epilepsy incidence. There is limited evidence regarding UK inequalities in adverse outcomes.
    CONCLUSIONS: Socioeconomic inequalities in epilepsy incidence are evident in the UK. To develop an evidence-based public health response to epilepsy, further research is needed to understand the populations affected, factors determining the association, and the extent of inequalities in adverse outcomes.
    BACKGROUND: Epilepsy Research Institute UK.
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