small animals

小动物
  • 文章类型: Journal Article
    电化学疗法(ECT)是将细胞膜的电穿孔与化学疗法相结合以促进非渗透性分子转运到细胞中的治疗方式。一些犬科和猫科动物的研究显示了有希望的结果,提示ECT可以成为某些肿瘤的有效辅助治疗或替代治疗选择。本文的目的是提供有关ECT在兽医学中的原理和应用的书目综述,并将其与人类医学中的应用进行比较。
    Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Several canine and feline studies have shown promising results, suggesting that ECT can be a valid adjuvant or alternative treatment option for some tumours. The objective of this paper is to provide a bibliographic review of the principles and applications of ECT in veterinary medicine and to compare to its use in human medicine.
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  • 文章类型: Systematic Review
    生酮饮食(KD)已经用于治疗人类癫痫大约一个世纪,最近,它们已经被植入癌症患者,以及肥胖的治疗。这种类型的饮食包括高脂肪水平,足量的蛋白质和限制的碳水化合物,或高中链甘油三酯。最近,生酮饮食在兽医学中引起了人们的关注,并且发表了评估KD对癫痫犬的影响的研究。这篇综述的目的是强调最近关于KD在狗和猫中应用的研究,来描述KD改善癫痫危机的神经生化机制,以及它们的不利影响。通过对PubMed上现有文献的系统回顾来确定研究,Embase,还有Scopus.纳入所有队列和病例对照研究,所有文章都出口到Mendeley®引文管理器,和重复项被自动删除。本研究包括七篇文章和三篇关于狗的会议摘要。有证据表明,食用含有中链甘油三酯的饮食会增加循环酮体的浓度并改善癫痫症状,尽管与经典KD相比,这些饮食具有更高的碳水化合物和更低的脂肪含量。
    Ketogenic diets (KD) have been used in the treatment of epilepsy in humans for around a century and, more recently, they have been implanted for cancer patients, as well as in the treatment of obesity. This type of diet consists of high-fat levels, an adequate amount of protein and restricted carbohydrates, or high medium-chain triglycerides. Recently, the ketogenic diet has gained attention in veterinary medicine and studies were published evaluating the effects of KD in dogs with epilepsy. The objective of this review was to highlight recent studies about the application of KD in dogs and cats, to describe the neurobiochemical mechanisms through which KD improves epilepsy crisis, and their adverse effects. Studies were identified by a systematic review of literature available on PubMed, Embase, and Scopus. All cohort and case-control studies were included, and all articles were exported to Mendeley® citation manager, and duplicates were automatically removed. Seven articles and three conference abstracts conducted with dogs were included in the present study. There is evidence that the consumption of diets with medium-chain triglycerides increases the concentration of circulating ketone bodies and improves epilepsy signs, although these diets have higher carbohydrate and lower fat content when compared to the classic KD.
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  • 文章类型: Journal Article
    锥形连接锁定板(CCP)已成为兽医骨科和创伤学中的有趣替代品。这方面的现有数据,然而,必须谨慎解释,和一些研究仍然需要得出关于这些植入物的临床使用的明确结论。在这种情况下,这篇综述旨在讨论CCP在小动物中的应用和机械方面,体外和离体研究结果。
    Conical coupling locking plates (CCP) have become an interesting alternative in veterinary orthopedics and traumatology. Available data in this regard, however, must be interpreted with caution, and several studies are still required to reach definitive conclusions on the clinical use of these implants. In this context, this review aims to discuss CCP applications and mechanical aspects in small animals and summarize in vivo, in vitro and ex vivo study results.
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  • 文章类型: Journal Article
    In veterinary surgery, single incision laparoscopic surgery (SILS) techniques have been described since 2009, and, in recent decades, many authors have reported the application of SILS in small animals, thus, promoting the wide dissemination of this novel approach among veterinary laparoscopists. The aim of this literature review is to provide a critical evaluation of the scientific reports on SILS in the field of small animal laparoscopic surgery. A comprehensive literature review was performed including from 1 January 2009 to 1 July 2020. The following data were recorded from each study: the design, year of publication, surgical procedure, species, number of animals included, and surgical time. The type of SILS technique and type of control group technique were evaluated. In total, 90 articles were identified through database searches and manual searches. The qualitative analysis showed that most of the articles were retrospective studies, without a control group or case series. A meta-analysis was performed on the eight controlled studies, showing that SILS ovariectomy and gastrointestinal procedures had a comparable surgical time to multiport techniques. The study of the articles available in the veterinary literature did not allow for an adequate meta-analysis of the published results, especially regarding post-operative pain, evaluations of surgical times, and post-operative complications in comparison to multiport techniques. Therefore, veterinary surgeons who want to employ these techniques must consider the real advantages of SILS techniques.
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