Abstract:
Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Several canine and feline studies have shown promising results, suggesting that ECT can be a valid adjuvant or alternative treatment option for some tumours. The objective of this paper is to provide a bibliographic review of the principles and applications of ECT in veterinary medicine and to compare to its use in human medicine.
摘要:
电化学疗法(ECT)是将细胞膜的电穿孔与化学疗法相结合以促进非渗透性分子转运到细胞中的治疗方式。一些犬科和猫科动物的研究显示了有希望的结果,提示ECT可以成为某些肿瘤的有效辅助治疗或替代治疗选择。本文的目的是提供有关ECT在兽医学中的原理和应用的书目综述,并将其与人类医学中的应用进行比较。