separation

分离
  • 文章类型: Journal Article
    介孔二氧化硅SBA-15由于其独特的结构和物理化学性质,已成为一种有前途的吸附和分离材料。为了进一步提高其性能,各种表面改性策略,包括金属氧化物和贵金属的掺入,以改善催化活性和稳定性,用氨基和巯基进行有机官能化,以增强吸附能力和选择性,和无机-有机复合改性的协同效应,进行了广泛的探索。本文综述了SBA-15用于吸附和分离应用的表面改性的最新进展。合成方法,结构特性,并讨论了SBA-15的优点,然后详细分析了不同的改性策略及其结构-性能关系。功能化SBA-15材料在有机污染物去除中的吸附分离性能,重金属离子,气体,和生物分子,以及在色谱和固液分离中,进行批判性评估。尽管取得了重大进展,确定了未来研究的挑战和机遇,包括开发低成本和可持续的合成路线,合理设计具有定制性能的SBA-15基材料,并融入实际应用。这篇综述旨在指导未来的研究工作,以开发用于可持续环境和工业应用的先进SBA-15基材料。强调绿色和可扩展的修改策略。
    Mesoporous silica SBA-15 has emerged as a promising adsorbent and separation material due to its unique structural and physicochemical properties. To further enhance its performance, various surface modification strategies, including metal oxide and noble metal incorporation for improved catalytic activity and stability, organic functionalization with amino and thiol groups for enhanced adsorption capacity and selectivity, and inorganic-organic composite modification for synergistic effects, have been extensively explored. This review provides a comprehensive overview of the recent advances in the surface modification of SBA-15 for adsorption and separation applications. The synthesis methods, structural properties, and advantages of SBA-15 are discussed, followed by a detailed analysis of the different modification strategies and their structure-performance relationships. The adsorption and separation performance of functionalized SBA-15 materials in the removal of organic pollutants, heavy metal ions, gases, and biomolecules, as well as in chromatographic and solid-liquid separation, is critically evaluated. Despite the significant progress, challenges and opportunities for future research are identified, including the development of low-cost and sustainable synthesis routes, rational design of SBA-15-based materials with tailored properties, and integration into practical applications. This review aims to guide future research efforts in developing advanced SBA-15-based materials for sustainable environmental and industrial applications, with an emphasis on green and scalable modification strategies.
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  • 文章类型: Journal Article
    目标:描述在COVID-19大流行期间,用于减轻住院的急性和重症监护患者及其家人之间强制分离的影响的护理策略。
    方法:根据JBI方法进行范围审查。
    方法:那些急性和重症监护领域,往往出乎意料,紧急发作的疾病或损伤得到了治疗。
    方法:2020年3月至2023年9月在Medline上用英语和法语撰写的文章,CINAHL完成,APAPsycInfo,包括符合我们纳入标准的Embase和CochraneCOVID-19研究注册数据库。灰色文献包括论文,论文和基本比勒费尔德学术搜索引擎。
    结果:在筛选的1357篇文章中,46符合纳入标准。大多数文章在北美发表。成人重症监护病房是最常报告的设置,其次是新生儿重症监护病房。最常报道的策略是虚拟电话或视频通信。大多数创新战略都涉及单位一级的跨专业合作。核心组成部分包括提供相关护理实践,虚拟访问,量身定制的信息,促进家庭成员之间的关系,关于生命终结的姑息治疗支持,以及住院和COVID-19的一般信息。儿科护理设置比成人护理设置更有可能适应身体探视。
    结论:护士使用同步,情节,和结构化的虚拟交互,无论是单独还是作为跨专业团队的一部分,在急性和重症监护环境中,减轻COVID-19大流行期间患者和家属之间的分离。
    结论:需要在急性和重症监护环境中进行永久性政策变更,以便为护士提供支持,以减轻患者和家庭的分离。我们建议将家庭成员视为照顾者和照顾者,在急性和重症监护环境中,不是以患者和家庭为中心的护理的访客。
    OBJECTIVE: To describe the nursing strategies used to mitigate the impact of forced separation between hospitalized acute and critical care patients and their families during the COVID-19 pandemic.
    METHODS: A scoping review was performed in accordance with JBI methodology.
    METHODS: Those acute and critical care areas in which sudden, often unexpected, emergent episodes of illness or injury were treated.
    METHODS: Articles written in English and French between March 2020 and September 2023 in Medline, CINAHL Complete, APA PsycInfo, Embase and the Cochrane COVID-19 study register databases that met our inclusion criteria were included. Gray literature included dissertations, theses and Base Bielefeld Academic Search Engines.
    RESULTS: Among the 1,357 articles screened, 46 met the criteria for inclusion. Most of the articles were published in North America. Adult critical care units were the most frequently reported settings, followed by neonatal intensive care units. The most frequently reported strategies were virtual telephone or video communications. A majority of the innovative strategies involved interprofessional collaboration at the unit level. Core components included the provision of relational nursing practices, virtual visits, tailored information, fostering relationships between family members, palliative care support regarding end of life, and general information about hospitalization and COVID-19. Pediatric care settings were more likely than adult care settings to accommodate physical visitation.
    CONCLUSIONS: Nurses used synchronous, episodic, and structured virtual interactions, either alone or as part of an interprofessional team, to mitigate separation between patients and families during the COVID-19 pandemic in acute and critical care settings.
    CONCLUSIONS: Permanent policy changes are needed across acute and critical care settings to provide support for nurses in mitigating patient and family separation. We recommend that family members be considered as caregivers and care receivers, not visitors in patient and family-centered care in acute and critical care settings.
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  • 文章类型: Journal Article
    生物分子,特别是蛋白质,多糖,和次生代谢物是潜在的先导化合物,因为它们具有显著的药理特性。然而,生物分子复杂的分子结构使其分离过程面临巨大挑战。传统的下游过程需要效率较低的多步骤协议,高溶剂消耗,贵,耗时,和费力。因此,双水相体系(ATPS)是从复杂混合物中提取和纯化生物分子的可靠技术。ATPS是一种环保,简单,成本有效,和易于扩展的过程。在单个过程中同时分离具有工业价值的生物分子需要短的处理时间。还通过引入低共熔溶剂进行了修改,离子液体,碳水化合物,氨基酸或共聚物,以提高产量,提高工艺效率,回收的生物分子的纯度和生物活性。这篇综述试图回顾最近开发的ATPS及其提取效率,隔离,并纯化生物分子,如蛋白质,多糖,次生代谢产物和其他生物物质。该综述提供了对ATPS用于生物分子回收的可行性和可靠性的见解。
    Biomolecules, specifically proteins, polysaccharides, and secondary metabolites are potential lead compounds due to their remarkable pharmacological properties. However, the complex molecular structure of the biomolecules makes their separation processes of great challenges. The conventional downstream processes require multistep protocols that are less efficient, high solvent consumption, expensive, time-consuming, and laborious. Hence, aqueous two-phase system (ATPS) is a reliable technique for the extraction and purification of biomolecules from a complex mixture. ATPS is an environmentally friendly, simple, cost effective, and easily scalable process. It requires a short processing time to separate biomolecules of industrial values simultaneously in a single process. Modifications have also been performed by introducing deep eutectic solvents, ionic liquids, carbohydrates, amino acids or copolymers to enhance the process efficiency with an increased yield, purity and bioactivity of recovered biomolecules. This review attempts to review the recent developed ATPSs and their efficiency to extract, isolate, and purify biomolecules such as proteins, polysaccharides, secondary metabolites and other biological substances. The review provides insights into the feasibility and reliability of ATPS for biomolecule recovery.
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  • 文章类型: Journal Article
    现代科学在重矿物应用方面的最新进展,工程,几十年来,技术和冶金工业特别是核能和电力工业的需求显着增加。这是重矿物产品的关键性和商业化的原因,也需要工业对其的高需求。重质矿物的回收,例如:来自其矿床的Zr和Ti伴生矿物依赖于来自复杂矿物的过渡金属和难熔金属的提取冶金。根据矿物浓缩和金属提取的有效性和效率,在他们的恢复过程中遇到了一些挑战,特别是在它们与相关的矿物杂质或脉石的分离中。然而,这篇综述的重点是研究磁性和静电物理处理技术及其在重矿物选矿和回收中的应用。因此,这将是,作为减少工艺步骤和提取复杂性的工具,涉及到溶解和湿法冶金过程的下游措施的矿物。
    Recent advancements in the applications of heavy minerals by modern science, engineering, technological and metallurgical industries especially in the demand by nuclear and power industries have significantly increased over the decades. This is the reason for the criticality and commerciality of products of heavy minerals and also necessitated their high demand by industries. The recovery of heavy minerals, such as: Zr and Ti associated minerals from their deposits is dependent on extractive metallurgy of transition and refractory metals from complex minerals. Based on the effectiveness and efficiency of mineral concentration as well as metal extraction, several challenges have been encountered in their recovery process, especially in their separation from associated mineral impurities or gangue. This review is however focused on investigating magnetic and electrostatic physical processing techniques and their applications in the beneficiation and recovery of heavy minerals. This will therefore, serve as a tool in reducing process steps and extraction complexity involved in downstream measures of dissolution and hydrometallurgical processes of the minerals.
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  • 文章类型: Journal Article
    出于健康和安全原因,寻找绿色,健康,具有良好口感的低热量甜味剂已成为许多消费者的需求。此外,对天然来源的糖替代品的需求急剧增加。在这次审查中,我们简要讨论了甜菊糖甜味剂的安全和健康益处,并列举了甜菊糖苷(SGs)的生理功能的一些例子,如抗炎,抗肥胖,抗高血压药,抗糖尿病,和反病毒,引用与它们在食品工业中的应用有关的各种证据。讨论了提取和纯化SGs的新兴技术以及过程变量和操作策略的最新进展。还证明了提取方法的影响及其与常规技术的比较。这些技术使用最少的能源溶剂,简化后续纯化阶段,使可行的替代品适合可能的工业应用。此外,我们还阐明了推进和应用天然甜味剂SGs的潜力。
    For health and safety reasons, the search for green, healthy, and low-calorie sweeteners with good taste has become the demand of many consumers. Furthermore, the need for sugar substitutes of natural origin has increased dramatically. In this review, we briefly discussed the safety and health benefits of stevia sweeteners and enumerated some examples of physiological functions of steviol glycosides (SGs), such as anti-inflammatory, anti-obesity, antihypertensive, anti-diabetes, and anticaries, citing various evidence related to their application in the food industry. The latest advances in emerging technologies for extracting and purifying SGs and the process variables and operational strategies were discussed. The impact of the extraction methods and their comparison against the conventional techniques have also been demonstrated. These technologies use minimal energy solvents and simplify subsequent purification stages, making viable alternatives suitable for a possible industrial application. Furthermore, we also elucidated the potential for advancing and applying the natural sweeteners SGs.
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  • 文章类型: Journal Article
    来自有机废物发酵的高附加值产品在现代社会已引起越来越多的关注。VFA是短链脂肪酸,在有机物的厌氧发酵过程中作为中间产物产生。VFA可以作为生产可替代燃料的重要有机碳源,微生物脂肪和油,和合成生物降解塑料等。从发酵液中提取VFA是一项具有挑战性的任务,因为悬浮液的组成相当复杂。在本文中,全面审查VFA生产方法,提供提取和分离。首先,简要回顾了提高VFA产量和重要操作参数的方法。其次,各种VFA提取和分离技术的评估和详细讨论,包括膜分离,复杂的提取,和吸附方法,被呈现,强调它们的具体优势和局限性。最后,强调了不同分离技术和提高工艺性能的新方法所遇到的挑战,为有效回收有机废弃物中的VFAs提供理论指导。
    High value-added products from organic waste fermentation have garnered increasing concern in modern society. VFAs are short-chain fatty acids, produced as intermediate products during the anaerobic fermentation of organic matter. VFAs can serve as an essential organic carbon source to produce substitutable fuels, microbial fats and oils, and synthetic biodegradable plastics et al. Extracting VFAs from the fermentation broths is a challenging task as the composition of suspensions is rather complex. In this paper, a comprehensive review of methods for VFAs production, extraction and separation are provided. Firstly, the methods to enhance VFAs production and significant operating parameters are briefly reviewed. Secondly, the evaluation and detailed discussion of various VFAs extraction and separation technologies, including membrane separation, complex extraction, and adsorption methods, are presented, highlighting their specific advantages and limitations. Finally, the challenges encountered by different separation technologies and novel approaches to enhance process performance are highlighted, providing theoretical guidance for recycling VFAs from organic wastes efficiently.
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  • 文章类型: Journal Article
    使用柔性支气管镜检查进行肺隔离和单肺通气的双腔管或支气管阻滞剂定位需要特定的技术能力。获得和保留这些技能的培训仍然是胸部麻醉的挑战。模拟领域最近的技术和创新发展开辟了令人兴奋的新视野和可能性。在这篇叙述性评论中,我们在调查的同时研究现有培训模式的最新发展,特别是,使用新兴技术,如虚拟现实支气管镜模拟,虚拟气道内窥镜检查,或术前气道的3D打印。本文的目的是,因此,总结训练模型/模拟器和虚拟现实模拟器在训练柔性支气管镜和肺隔离胸腔镜麻醉中的现有和未来应用作用。
    A double-lumen tube or bronchial blocker positioning using flexible bronchoscopy for lung isolation and one-lung ventilation requires specific technical competencies. Training to acquire and retain such skills remains a challenge in thoracic anesthesia. Recent technological and innovative developments in the field of simulation have opened up exciting new horizons and possibilities. In this narrative review, we examine the latest development of existing training modalities while investigating, in particular, the use of emergent techniques such as virtual reality bronchoscopy simulation, virtual airway endoscopy, or the preoperative 3D printing of airways. The goal of this article is, therefore, to summarize the role of existing and future applications of training models/simulators and virtual reality simulators for training flexible bronchoscopy and lung isolation for thoracic anesthesia.
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  • 文章类型: Journal Article
    背景:牛奶脂肪球膜(MFGM)是存在于牛奶乳液中的薄膜,悬浮在乳脂球表面,并且包含多种生物活性成分。MFGM研究的最新进展引起了人们对其生物学特性和健康相关功能的兴趣。彻底探索和利用MFGM作为乳乳剂中重要的生物活性成分,可以以积极的方式深刻影响人类健康。范围和方法:本审查全面审查了在理解结构方面的当前进展,composition,物理化学性质,分离和纯化的方法,和MFGM的生物活性。此外,它强调了MFGM在开发添加剂和药物输送系统方面的巨大潜力,特别关注利用存在于MFGM上的蛋白质和磷脂的表面活性和稳定性来生产天然乳化剂和药物包封材料。
    结论:MFGM含有多种具有多种生理功能的活性物质,包括促进消化,维持肠粘膜屏障,促进神经发育。通常用作婴儿配方食品中的膳食补充剂,MFGM的特殊表面活性推动了其成为天然乳化剂或封装材料的发展。这种表面活性主要来源于极性脂质的两亲性和高度糖基化的蛋白质所表现出的稳定性。
    BACKGROUND: The milk fat globule membrane (MFGM) is a thin film that exists within the milk emulsion, suspended on the surface of milk fat globules, and comprises a diverse array of bioactive components. Recent advancements in MFGM research have sparked a growing interest in its biological characteristics and health-related functions. Thorough exploration and utilization of MFGM as a significant bioactive constituent in milk emulsion can profoundly impact human health in a positive manner. Scope and approach: This review comprehensively examines the current progress in understanding the structure, composition, physicochemical properties, methods of separation and purification, and biological activity of MFGM. Additionally, it underscores the vast potential of MFGM in the development of additives and drug delivery systems, with a particular focus on harnessing the surface activity and stability of proteins and phospholipids present on the MFGM for the production of natural emulsifiers and drug encapsulation materials.
    CONCLUSIONS: MFGM harbors numerous active substances that possess diverse physiological functions, including the promotion of digestion, maintenance of the intestinal mucosal barrier, and facilitation of nerve development. Typically employed as a dietary supplement in infant formula, MFGM\'s exceptional surface activity has propelled its advancement toward becoming a natural emulsifier or encapsulation material. This surface activity is primarily derived from the amphiphilicity of polar lipids and the stability exhibited by highly glycosylated proteins.
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  • 文章类型: Systematic Review
    海洋低聚糖由于具有多种生理活性而被广泛应用于工业领域。然而,不同聚合度(Dps)的寡糖在生理活性和适用领域上有所不同。因此,分离是有希望和必要的,纯化和结构表征这些寡糖,以了解它们的结构-功能关系。这篇综述将总结分离的持续发展,海洋寡糖的纯化和结构表征,包括藻酸盐寡糖,角叉菜胶寡糖,琼脂寡糖,甲壳素寡糖和壳寡糖,强调分离和纯化方法的成功例子。此外,还包括在食品生物技术和农业领域制备功能性寡糖的前景。该综述无疑可以促进海洋功能性多糖在食品和农业中的利用。
    Marine oligosaccharides have now been applied in a wide range of industry due to various kinds of physiological activities. However, the oligosaccharides with different polymeric degrees (Dps) differed in physiological activities and applicable fields. So it is promising and essential to separate, purify and structurally characterize these oligosaccharides for understanding their structure-function relationship. This review will summarize the lasted developments in the separation, purification and structural characterization of marine oligosaccharides, including the alginate oligosaccharides, carrageenan oligosaccharides, agar oligosaccharides, chitin oligosaccharides and chitosan oligosaccharides, emphasizing the successful examples of methods for separation and purification. Furthermore, an outlook for preparation of functional oligosaccharides in food biotechnology and agriculture fields is also included. This comprehensive review could definitely promote the utilization of marine functional polysaccharides for food and agriculture.
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  • 文章类型: Journal Article
    在这项研究中,我们回顾了将微流体液滴中的样品处理与不同分离技术相结合的各种策略,包括液相色谱,质谱,和毛细管电泳。与液滴微流体接口的分离技术代表了分析化学的新兴趋势,其中微飞升液滴用作微反应器,分析模块之间的桥梁,以及样品处理和分离/检测步骤之间的目标分析物的载体。这可以克服分离科学中遇到的障碍,尤其是模块集成度低,工作卷不兼容,以及不同操作阶段之间的交叉污染。对于这种液滴分离接口的目的,这篇评论涵盖了截至2023年5月关于这一主题的所有作品的不同工具设计,以及我们对各自优势和考虑因素的观点。还讨论了针对有限样品体积的液滴接口分离策略的演示和性能。
    In this study, we review various strategies to couple sample processing in microfluidic droplets with different separation techniques, including liquid chromatography, mass spectrometry, and capillary electrophoresis. Separation techniques interfaced with droplet microfluidics represent an emerging trend in analytical chemistry, in which micro to femtoliter droplets serve as microreactors, a bridge between analytical modules, as well as carriers of target analytes between sample treatment and separation/detection steps. This allows to overcome the hurdles encountered in separation science, notably the low degree of module integration, working volume incompatibility, and cross contamination between different operational stages. For this droplet-separation interfacing purpose, this review covers different instrumental designs from all works on this topic up to May 2023, together with our viewpoints on respective advantages and considerations. Demonstration and performance of droplet-interfaced separation strategies for limited sample volumes are also discussed.
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