printing

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  • 文章类型: Letter
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  • 文章类型: Case Reports
    背景:拔除后和植入物放置前遇到保留的根尖是可能的临床并发症。有许多方法可以去除可能是创伤性或无创伤的残留根。不管采用哪种方法,仔细的治疗计划对于减少并发症很重要,降低发病率,并保留骨骼结构。当前案例研究的目的是介绍一种技术和数字生成设备,用于识别和无损伤地去除保留的根尖,并同时放置稳定的牙科植入物。
    方法:一名63岁女性,有心肌梗死史,高血压,和急性胰腺炎出现在植入位置#5。临床检查显示足够的咬合,中端,和用于植入物放置的颊舌尺寸。使用锥形束计算机断层扫描的射线照相检查显示,保留的根#5干扰了植入物的放置。使用数字计划以最小的创伤提取根尖,以保持足够的骨骼以同时放置植入物并具有良好的主要稳定性。
    结果:第1、3、6周和第4、8、10个月的随访显示骨整合植入物保存良好。
    结论:采用数字计划来创建pal窗可以非常准确地去除保留的根部,同时保持骨整合良好的牙科植入物的骨基础。
    结论:使用锥形束计算机断层扫描与口内数字扫描相结合的预先计划对于精确定位保留的根部和正确的植入物放置以及出色的主要稳定性是必要的。数字计划的3D手术导向器是用于在植入物放置期间提取保留的根部以最小化骨损伤的有用方法。数字规划提供了精确和微创植入手术。
    BACKGROUND: Encountering a retained root tip post-extraction and prior to implant placement is a possible clinical complication. There are numerous approaches for removing retained roots that may be traumatic or atraumatic. Regardless of the approach, careful treatment planning is important to minimize complications, reduce morbidity, and preserve bony structures. The aim of the current case study is to introduce a technique and digitally generated device used for identifying and atraumatically removing a retained root tip and simultaneously placing a stable dental implant.
    METHODS: A 63-year-old female with a history of myocardial infarction, hypertension, and acute pancreatitis presented for implant placement at site #5. Clinical examination revealed adequate interocclusal, mesiodistal, and buccolingual dimensions for implant placement. Radiographic examination using cone beam computed tomography revealed that retained root #5 interfered with implant placement. Digital planning was used to extract the root tip with minimal trauma to maintain adequate bone for simultaneous implant placement with good primary stability.
    RESULTS: The follow-ups at 1, 3, and 6 weeks and 4, 8, and 10 months revealed good bone preservation with an osseointegrated implant.
    CONCLUSIONS: Employment of digital planning to create a palatal window allowed excellent accuracy in removing the retained root while maintaining the bony foundation for a well osseointegrated dental implant.
    CONCLUSIONS: Pre-planning using cone beam computed tomography scan merged with an intraoral digital scan is necessary for precise location of a retained root and correct implant placement with excellent primary stability. A digitally planned 3D surgical guide is a useful method for extracting retained roots during implant placement to minimize bone damage. Digital planning provides a precise and minimally invasive implant surgery.
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  • 文章类型: Journal Article
    垂直和合并骨缺损的牙槽骨重建是一种不可预测的过程,其成功率各不相同。垂直和组合骨增强的最大挑战是保持骨移植物的机械稳定性;因此,必须提供和保留骨骼再生的空间。生物材料和3D打印的发展使得聚合物支架能够用于重建牙槽嵴缺损。这项初步研究的目的是评估创新的个性化可生物降解聚乳酸(PLA)支架的机械特性,在动态条件下,模拟生物降解和咀嚼力的影响。经过PLA支架的设计和3D打印,根据压缩测试程序,形成两组27个支架。在咬合和横向方向上进行压缩测试。在两组中,在体外降解过程中,在不同的测试阶段形成了三个支架的9个亚组,总共16周。结果表明,生物降解和负载施加对测试支架的力学特性没有显着影响。可以得出结论,模拟的咀嚼力和生物降解不会显着影响个性化的生物可降解增强支架的机械特性。
    The alveolar ridge reconstruction of vertical and combined bone defects is a non-predictable procedure with varying percentages of success. The greatest challenge for vertical and combined bone augmentation is to maintain mechanical stability of the bone graft; therefore, it is mandatory to provide and preserve space for bone regeneration. The development of biomaterials and 3D printing has enabled the use of polymer scaffolds in the reconstruction of alveolar ridge defects. The aim of this pilot study was to evaluate the mechanical characteristics of an innovative individualized biodegradable polylactic acid (PLA) scaffold, under dynamic conditions, simulating biodegradation and the influence of masticatory forces. After the design and 3D printing of PLA scaffolds, two groups of 27 scaffolds were formed according to the compression testing procedure. The compression tests were performed in occlusal and lateral directions. In each of the two groups, nine subgroups of three scaffolds were formed for different testing periods during in vitro degradation with a total period of 16 weeks. Results showed that biodegradation and load application had no significant influence on mechanical characteristics of tested scaffolds. It can be concluded that simulated masticatory forces and biodegradation do not significantly influence the mechanical characteristics of an individualized biodegradable augmentation scaffold.
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  • 文章类型: Observational Study
    根据窗口的存在,三维(3D)打印的钛(3D-Ti)笼的市售设计可以分为两种类型:具有允许填充骨移植材料的窗口的笼和用于独立使用的非窗口笼。这项前瞻性观察性病例系列研究旨在探讨在联合开窗和非开窗笼子植入的情况下使用非开窗型3D-Ti笼子的临床可行性。此外,我们评估了非窗笼的骨生长模式及其与已发表的融合分级系统的相关性。
    共纳入了31例接受单级腰椎后路椎间融合术的连续患者。插入两个具有不同设计的3D-Ti笼:左侧的非窗笼和右侧的窗笼。X线融合由弯曲和伸展X线照片(F-E角)和计算机断层扫描上的笼子桥接骨(CBB)评分之间的节段角度定义。分析了F-E角与包括表面骨整合比(SOR)评分在内的骨整合评分系统之间的关联。
    31例患者中有27例(87%)在术后12个月实现了影像学融合。在非窗口笼子里,31人中有23人(74.2%)有公平的SOR分数,而31个窗口笼子中有19个(61.3%)的笼子内CBB评分相当。SOR分数越高,屈伸角度越小(SOR0与SOR1:6.30°±2.43°vs.1.95°±0.99°,p<0.001;SOR0与SOR2:6.03°±2.43°vs.0.99°±0.74°,p<0.001)。
    在腰椎椎间融合术中使用无窗3D-Ti笼的临床可行性可能是可以接受的。此外,新提出的使用非窗笼的融合准则,SOR分数,显示出与已发布的融合分级系统的显着关联,证明了其在腰椎手术中确定椎间融合的可行性。
    UNASSIGNED: The commercially available design of a three-dimensional (3D)-printed titanium (3D-Ti) cage can be divided into two types according to the presence of a window: a cage with a window that allows filling of bone graft materials and a non-window cage for stand-alone use. This prospective observational case series study aimed to explore the clinical feasibility of using a non-window type 3D-Ti cage in cases of combined window and non-window cage implantation. Furthermore, we evaluated the bone in growth patterns of non-window cages and their correlation with published fusion grading systems.
    UNASSIGNED: A total of 31 consecutive patients who underwent single-level posterior lumbar interbody fusion surgery were included. Two 3D-Ti cages with different designs were inserted: a non-window cage on the left side and a window cage on the right side. Radiographic fusion was defined by the segmental angle between flexion and extension radiographs (F-E angle) and cage bridging bone (CBB) scores on computed tomography. The association between the F-E angle and osteointegration scoring system including the surface osteointegration ratio (SOR) score was analyzed.
    UNASSIGNED: Radiographic fusion was achieved in 27 of 31 patients (87%) at 12 months postoperatively. Among the non-window cages, 23 of 31 (74.2%) had fair SOR scores, while 19 of 31 (61.3%) window cages had fair intra-cage CBB scores. The higher the SOR score was, the smaller the flexion-extension angle (SOR 0 vs. SOR 1: 6.30° ± 2.43° vs. 1.95° ± 0.99°, p < 0.001; SOR 0 vs. SOR 2: 6.03° ± 2.43° vs. 0.99°± 0.74°, p < 0.001).
    UNASSIGNED: The clinical feasibility of using a non-window 3D-Ti cage during lumbar interbody fusion might be acceptable. Furthermore, a newly suggested fusion criterion for the use of the non-window cage, the SOR score, showed a significant association with the published fusion grading systems, demonstrating its feasibility in determining interbody fusion in lumbar spinal surgery.
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  • 文章类型: Journal Article
    基于三维(3D)打印技术和使用预弯曲板的内部重新定位方法在正颌手术中越来越受欢迎。然而,对影响准确性的临床因素的方法和研究仍有进一步改进的空间.这个单一中心,前瞻性研究包括34例患者,旨在评估使用预弯曲锁定钢板进行上颌和下颌复位的准确性和影响因素。在计划位置的3D打印模型上手动预弯曲板,和他们的孔的位置进行扫描和复制术中与截骨引导。在设定的地标下,在三个轴上计算了重新定位和板孔定位的精度。还验证了以下影响重新定位精度的临床因素:板孔定位的偏差,计划的移动量,和模拟的骨干扰量。术前计划和术后结果之间的重新定位和孔定位的中位数偏差为0.26mm和0.23mm,分别,在上颌骨,0.69毫米和0.36毫米,分别,在下颌骨,表明该方法是高度准确的,基于板孔和形状匹配的重新定位概念在上颌骨中更有效。相关测试的结果表明,上/下方向的大量骨干扰和板孔定位错误会降低下颌重新定位的准确性。
    In-house repositioning methods based on three-dimensional (3D)-printing technology and the use of pre-bent plates has been gaining popularity in orthognathic surgery. However, there remains room for further improvement in methods and investigations on clinical factors that affect accuracy. This single-centre, prospective study included 34 patients and aimed to evaluate the accuracy and factors influencing maxillary and mandibular repositioning using pre-bent locking plates. The plates were manually pre-bent on the 3D-printed models of the planned position, and their hole positions were scanned and reproduced intraoperatively with osteotomy guides. The accuracy of repositioning and plate-hole positioning was calculated in three axes with the set landmarks. The following clinical factors that affect repositioning accuracy were also verified: deviation of the plate-hole positioning, amount of planned movement, and amount of simulated bony interference. The median deviations of the repositioning and hole positioning between the preoperative plan and postoperative results were 0.26 mm and 0.23 mm, respectively, in the maxilla, and 0.69 mm and 0.36 mm, respectively, in the mandible, suggesting that the method was highly accurate, and the repositioning concept based on the plate hole and form matching was more effective in the maxilla. Results of the correlation test suggest that large amounts of bony interference and plate-hole positioning errors in the up/down direction could reduce mandibular repositioning accuracy.
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  • 文章类型: Journal Article
    背景:创新项目的高失败率促使我们了解主要利益相关者对提高成功率的阻力和障碍的看法。
    目的:本研究旨在分析加泰罗尼亚三级医院在实施3D打印项目之前的实施准备情况。
    方法:我们使用了基于Web的,自愿,以及使用标准化测量发展问卷(NoMAD)进行的匿名调查,以收集来自德国TriasiPujol大学医院的一组选定的医疗保健专业人员的观点和看法。
    结果:在这项研究中,58名专业人士,包括服务负责人(n=30,51%),医生(n=18,31%),护士(n=7,12%),和支持人员(n=3,5%),回答了问卷。所有小组都看到了该项目的价值,并愿意注册和支持它。受访者报告认知参与得分最高(满分5分)(平均4.45,标准差0.04),相干性(平均值3.72,标准差0.13),和反射监测(平均3.80,标准差0.25)。得分最弱的是集体行动(平均3.52,SD0.12)。调查中各专业之间的分数没有统计学上的显着差异。
    结论:3D打印项目的实施要注意做好准备,定义,分享,并支持其使用和实施所涉及的业务工作。它也应该明白,评估,并传达新的实践集可以影响用户和周围其他人的方式。我们建议卫生官员和政治家将这种经验视为发展更有效的卫生创新系统的坚实基础,并作为转型的催化剂。
    The high failure rate of innovation projects motivates us to understand the perceptions about resistances and barriers of the main stakeholders to improving success rates.
    This study aims to analyze the readiness for change in the implementation of a 3D printing project in a Catalan tertiary hospital prior to its implementation.
    We used a web-based, voluntary, and anonymous survey using the Normalization Measurement Development questionnaire (NoMAD) to gather views and perceptions from a selected group of health care professionals at Germans Trias i Pujol University Hospital.
    In this study, 58 professionals, including heads of service (n=30, 51%), doctors (n=18, 31%), nurses (n=7, 12%), and support staff (n=3, 5%), responded to the questionnaire. All groups saw the value of the project and were willing to enroll and support it. Respondents reported the highest scores (out of 5) in cognitive participation (mean 4.45, SD 0.04), coherence (mean 3.72, SD 0.13), and reflective monitoring (mean 3.80, SD 0.25). The weakest score was in collective action (mean 3.52, SD 0.12). There were no statistically significant differences in scores among professions in the survey.
    The 3D printing project implementation should pay attention to preparing, defining, sharing, and supporting the operational work involved in its use and implementation. It should also understand, assess, and communicate the ways in which the new set of practices can affect the users and others around them. We suggest that health officers and politicians consider this experience as a solid ground toward the development of a more efficient health innovation system and as a catalyst for transformation.
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  • 文章类型: Journal Article
    目的:对比马蹄肾(HSK)患者的手术结果,其中有疑似癌症的局限性肾脏肿块与非融合的非异位肾脏患者,强调HSK的安全手术方法。
    方法:该研究检查了1971-2021年间梅奥诊所肾切除术注册的实体瘤。根据各种因素,每个HSK病例与三名非HSK患者相匹配。测量的结果包括手术后30天内的并发症,eGFR的变化,总的来说,癌症特异性,和无转移生存率。
    结果:34例HSKs中有30例患有恶性肿瘤,而非融合非异位参考队列中102例患者中有90例患有恶性肿瘤。93%的HSK病例存在副峡部动脉,43%表现出多个动脉,7%表现出6个或更多动脉。HSKs的估计失血量和手术时间显着增加(900vs.300ml,P=0.004;246与163分钟,分别为P<0.001)。HSK组的总体并发症发生率为26%(与17%的对象,p=0.2),3个月时eGFR的中位数变化为-8.5(vs.-8.1在引用中,p=0.8)。在5年的随访中,HSK患者的生存率为72%,91%,总体来说是69%,癌症特异性,和无转移生存率,分别。相应的比率为79%,86%,77%,分别,匹配的参考患者(p>0.05)。
    结论:HSK肿瘤治疗在技术上具有挑战性,出血较多;然而,数据显示HSK肿瘤患者的结果相当,包括并发症和生存率,那些在有经验的中心没有HSK的人。
    To contrast surgical outcomes of Horseshoe Kidney (HSK) patients with localized renal masses suspected of cancer with nonfused nonectopic kidney patients, emphasizing safe surgical practices for HSKs.
    The study examined solid tumors from the Mayo Clinic Nephrectomy registry between 1971 and 2021. Each HSK case was matched to three non-HSK patients based on various factors. The outcomes measured included complications within 30days of surgery, change in estimated glomerular filtration rate, and overall, cancer-specific, and metastasis-free survival rates.
    Thirty of the 34 HSKs had malignant tumors compared with 90 of the 102 patients in the nonfused nonectopic referent cohort. Accessory isthmus arteries were present in 93% of HSK cases, with 43% exhibiting multiple arteries and 7% with 6 or more arteries. Estimated blood loss and surgery duration were significantly higher in HSKs (900 vs 300 mL, P = .004; 246 vs 163 minutes, P < .001, respectively). The HSK group demonstrated an overall complication rate of 26% (vs 17% in referents, P = .2) and a median change in estimated glomerular filtration rate at 3months of - 8.5 (vs -8.1 in referents, P = .8). At 5-year follow-up, survival rates for HSK patients were 72%, 91%, and 69% for overall, cancer-specific, and metastasis-free survival, respectively. The corresponding rates were 79%, 86%, and 77%, respectively, for matched referent patients (P > .05).
    HSK tumor management is technically challenging with higher blood loss; however, the data demonstrate comparable outcomes for patients with HSK tumors, including complications and survival, to those without HSKs in experienced centers.
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    文章类型: Journal Article
    边缘配合是假肢修复成功的关键因素。这项研究旨在评估和比较通过三维(3D)打印和常规方法制造的内冠的边缘拟合。
    这在体外,实验研究评估了20个内冠,其中10个是通过3D打印制造的,10个是通过传统的蜡技术制造的。在立体显微镜下在8个点处测量边缘间隙。使用Shapiro-Wilk检验对结果进行了分析,配对t检验,独立t检验,单因素方差分析(α=0.05)。
    远端点的平均边缘间隙最大,对于常规制造的内冠,在颊点最小,总平均边缘间隙为99.67±4.59μm。按压前平均边缘间隙在近颊点最大,在颊点最小(总平均值为103.92±2.19μm),按压后在远颊点最大,在近颊点最小(总平均值为117.67±2.87μm)。根据配对t检验,在所有8点压制后,通过3D打印制造的内冠部的平均边际间隙显着增加,并且总体上也是如此。与按压前比较(P<0.001)。此外,与通过常规方法制造的相比,通过3D打印制造的内冠部在所有点的平均边际间隙均显着更大(独立t检验,P<0.001)。
    在这项体外研究的局限性内,结果表明,与3D打印相比,传统方法制造的内冠体具有明显的边缘拟合。
    UNASSIGNED: Marginal fit is a key factor in success of prosthetic restorations. This study aimed to assess and compare the marginal fit of endocrowns fabricated by three-dimensional (3D) printing and the conventional method.
    UNASSIGNED: This in vitro, experimental study evaluated 20 endocrowns, of which 10 were fabricated by 3D printing and 10 were fabricated by the conventional wax-up technique. The marginal gap was measured at 8 points under a stereomicroscope. The results were analyzed using the Shapiro-Wilk test, paired t-test, independent t-test, and one-way analysis of variance (α = 0.05).
    UNASSIGNED: The mean marginal gap was maximum at the distal point, and minimum at the buccal point for the conventionally fabricated endocrowns with an overall mean marginal gap of 99.67 ± 4.59 μm. The mean marginal gap was maximum at the mesiobuccal and minimum at the buccal point before pressing (overall mean of 103.92 ± 2.19 μm) before pressing, and maximum at the distobuccal and minimum at the mesiobuccal point after pressing (overall mean of 117.67 ± 2.87 μm). According to paired t-test, the mean marginal gap of endocrowns fabricated by 3D printing significantly increased after pressing at all 8 points and also in general, compared with before pressing (P < 0.001). Furthermore, the mean marginal gap at all points was significantly greater in endocrowns fabricated by 3D printing compared with those fabricated by the conventional method (independent t-test, P < 0.001).
    UNASSIGNED: Within the limitations of this in vitro study, the results showed that endocrowns fabricated by the conventional method had significantly superior marginal fit than those fabricated by 3D printing.
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  • 文章类型: Journal Article
    打印机可以释放大量的颗粒污染室内环境,并造成健康风险。明确打印机排放颗粒(PEPs)的暴露水平和理化性质将有助于评估打印机操作员的健康风险。在我们的研究中,长时间实时监测印刷厂的颗粒浓度(12小时/天,总共6天),收集PEPs来表征它们的物理化学性质,包括形状,大小和组成。结果表明,PEPs的浓度与印刷工作量密切相关,PM10和PM2.5的最高颗粒质量浓度分别为212.73μgm-3和91.48μgm-3。PM1在印刷车间的质量浓度范围为11.88-80.59μgm-3,和174.83-1348.84Pcm-3的计数值随打印量而变化。PEPs的粒径小于900nm,47.99%的PEPs小于200nm,14.21%的颗粒为纳米级。PEPs含有68.92%的有机碳(OC),5.31%元素碳(EC),3.17%金属元素,和22.60%的其他无机添加剂,其中含有比调色剂更多的OC和金属元素。总多环芳烃(PAHs)水平在调色剂中为18.95ng/mg,在PEP中为120.70ng/mg。PEPs中PAHs的致癌风险为1.40×10-7。这些研究结果表明,未来的研究应该更加关注暴露于纳米颗粒的印刷工人对健康的影响。
    Printers can release numerous particles to contaminate indoor environments and pose health risks. Clarifying the exposure level and physicochemical properties of printer-emitted particles (PEPs) will help to evaluate the health risks of printer operator. In our study, the particles concentration in the printing shop was monitored in real time for a long time (12 h/day, total 6 days), and the PEPs were collected to characterize their physicochemical properties including shape, size and compositions. The result showed that the concentration of PEPs is closely related to the printing workload and the highest particle mass concentration of PM10 and PM2.5 was 212.73 μg m-3 and 91.48 μg m-3, respectively. The concentration of PM1 in the printing shop was in the range of 11.88-80.59 μg m-3 for mass value, and 174.83-1348.84 P cm-3 for count value which changed with the printing volume. The particle sizes of PEPs were less than 900 nm, 47.99% of PEPs was less than 200 nm, and 14.21% of the particles were at the nanoscale. PEPs contained 68.92% organic carbon (OC), 5.31% elemental carbon (EC), 3.17% metal elements, and 22.60% other inorganic additives, which contained more OC and metal elements than toners. Total polycyclic aromatic hydrocarbons (PAHs) levels were 18.95 ng/mg in toner and 120.70 ng/mg in PEPs. The carcinogenic risk of PAHs in PEPs was 1.40 × 10-7. These findings suggested future studies should pay more attention to the health effects of printing workers exposed to nanoparticles.
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  • 文章类型: Journal Article
    背景:许多院士建议补充使用从放射学图像重建的3D打印模型,以实现最佳的解剖学教育。3D打印模型是我们可用的较新技术。这篇系统综述的目的是捕捉这项新技术在解剖学教育中的有用性或有效性。
    方法:22项研究符合定量合成的纳入和排除标准。纳入的研究根据干预措施和参与者进行分组。没有基于地理位置的限制,语言和出版年。随机化,对照试验,包括横截面和交叉设计。两个参与者中每个干预的效果大小被计算为标准化平均差(SMD)。
    结果:22个随机分组,纳入对照试验,对1435名参与者的知识获取效应大小进行定量评估,作为标准化平均差.3D打印模型的合并效应大小为0.77(0.45-1.09,95%CI,P<0.0001),异质性为86%。仅在三项研究中测量了准确性评分,估计效应大小为2.81(1.08-4.54,95%CI,P=0.001),异质性为92%。对6项研究的满意度进行问卷调查。估计效应大小为2.00(0.69-3.32,95%CI,P=0.003),具有显着的异质性。
    结论:暴露于3D打印模型的参与者比使用传统方法的参与者表现更好。因此,3D打印模型是解剖学教育的潜在工具。
    BACKGROUND: Many academicians suggested the supplementary use of 3D-printed models reconstructed from radiological images for optimal anatomy education. 3D-printed model is newer technology available to us. The purpose of this systematic review was to capture the usefulness or effectiveness of this newer technology in anatomy education.
    METHODS: Twenty-two studies met the inclusion and exclusion criteria for quantitative synthesis. The included studies were sub-grouped according to the interventions and participants. No restrictions were applied based on geographical location, language and publication years. Randomized, controlled trial, cross-sectional and cross-over designs were included. The effect size of each intervention in both participants was computed as a standardized mean difference (SMD).
    RESULTS: Twenty-two randomized, controlled trials were included for quantitative estimation of effect size of knowledge acquisition as standardized mean difference in 1435 participants. The pooled effect size for 3D-printed model was 0.77 (0.45-1.09, 95% CI, P < 0.0001) with 86% heterogeneity. The accuracy score was measured in only three studies and estimated effect size was 2.81 (1.08-4.54, 95% CI, P = 0.001) with 92% heterogeneity. The satisfaction score was examined by questionnaire in 6 studies. The estimated effect size was 2.00 (0.69-3.32, 95% CI, P = 0.003) with significant heterogeneity.
    CONCLUSIONS: The participants exposed to the 3D-printed model performed better than participants who used traditional methodologies. Thus, the 3D-printed model is a potential tool for anatomy education.
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