■2019年冠状病毒病(COVID-19)后遗症,也被称为长科维德,可以出现各种症状。在这些症状中,自主神经失调,尤其是体位性心动过速综合征(POTS),应该进行评估。然而,以前缺乏治疗POTS并发COVID-19的研究。因此,本研究旨在探讨长型COVID并发POTS的治疗过程。
■对主诉疲劳并符合POTS诊断标准的患者的病历进行审查。我们评估了治疗天数,方法和疲劳评分的变化,在Schellong测试中心率的变化,以及第一次和最后一次访问时的社会状况。
■随访32例长型COVID合并POTS患者(男性16例,中位年龄28岁)。随访时间为159天,COVID-19发病与初次住院之间的间隔为97天。一些患者对β受体阻滞剂治疗有反应。许多患者有精神症状,需要精神干预和选择性5-羟色胺再摄取抑制剂处方。心率的变化,性能状态,从第一次到最后一次访问,就业/教育状况有所改善。这些结果被认为是由于各种治疗干预和自发改善的影响。
■我们的研究表明,94%的POTS并发长COVID的患者的病情将在159天内得到改善。因此,当长型COVID患者抱怨疲劳时,应考虑POTS评估,应注意心理症状和社会背景。
UNASSIGNED: Coronavirus disease 2019 (COVID-19) sequelae, also known as long COVID, can present with various symptoms. Among these symptoms, autonomic dysregulation, particularly postural orthostatic tachycardia syndrome (POTS), should be evaluated. However, previous studies on the treatment of POTS complicated by COVID-19 are lacking. Therefore, this study aimed to investigate the treatment course of long COVID complicated by POTS.
UNASSIGNED: The medical records of patients who complained of fatigue and met the criteria for POTS diagnosis were reviewed. We evaluated the treatment days, methods and changes in fatigue score, changes in heart rate on the Schellong test, and social situation at the first and last visits.
UNASSIGNED: Thirty-two patients with long COVID complicated by POTS were followed up (16 males; median age: 28 years). The follow-up period was 159 days, and the interval between COVID-19 onset and initial hospital attendance was 97 days. Some patients responded to β-blocker therapy. Many patients had psychiatric symptoms that required psychiatric intervention and selective serotonin reuptake inhibitor prescription. Changes in heart rate, performance status, and employment/education status improved from the first to the last visit. These outcomes were believed to be because of the effects of various treatment interventions and spontaneous improvements.
UNASSIGNED: Our study suggests that the condition of 94% of patients with POTS complicated by long COVID will improve within 159 days. Therefore, POTS evaluation should be considered when patients with long COVID complain of fatigue, and attention should be paid to psychological symptoms and the social context.