older people

老年人
  • 文章类型: Journal Article
    背景:尽管人们对自然灾害后的脆弱性的了解越来越多,老年人的观点受到的关注有限。这项研究旨在探索老年人遇到2018年龙目岛地震的看法和经验。
    方法:这项探索性定性研究涉及16位居住在龙目岛2018年地震影响最严重的村庄之一的老年人,努沙登加拉巴拉特,印度尼西亚。数据是在2019年6月使用半结构化访谈收集的。参与者的回答被数字记录和逐字转录用于分析。使用NVivo管理的定性内容分析对数据进行分析。
    结果:从老年人的角度来看,产生了三个主题:在灾难中幸存下来,应对生活变化,在挑战和希望中导航。每个主题包括两个类别,这反映了老年人从灾难早期到后期的旅程。
    结论:老年人在身体和精神上都经历了危急的状况和困难。在接受灾难后的生活状况之前,他们还经历了各种情绪反应。护士应在灾后条件下满足老年人的身心健康需求方面发挥作用。
    结论:这项研究可以使护士和其他主要利益相关者了解自然灾害期间和之后老年人的需求。护士需要具备技能和能力,以在困难的情况下和有限的资源下识别和满足老年人的需求。
    BACKGROUND: Despite the growing knowledge of people\'s vulnerability following natural disasters, the perspective of older people has received limited attention. This study aimed to explore the perceptions and experiences of older people encountering the 2018 Lombok earthquakes.
    METHODS: This exploratory qualitative study involved 16 older people living in one of the villages most affected by the 2018 earthquakes in Lombok Island, Nusa Tenggara Barat, Indonesia. The data were collected in June 2019 using semi-structured interviews. Participants\' responses were digitally recorded and transcribed verbatim for analysis. The data were analysed using qualitative content analysis managed in NVivo.
    RESULTS: From older people\'s perspectives, three themes were generated: surviving the disaster, dealing with life changes and navigating through challenges and hope. Each theme comprised two categories, which reflected the journey of older people from the early to the later phase of the disaster.
    CONCLUSIONS: Older people experienced critical conditions and difficulties both physically and mentally. They also experienced various emotional responses before accepting living situations following a disaster. Nurses should play a role in fulfilling the physical and mental health needs of older people in post-disaster conditions.
    CONCLUSIONS: This study can inform nurses and other key stakeholders about the needs of older people during and after natural disasters. Nurses need to be equipped with the skills and abilities to identify and meet the needs of older people in difficult situations and with limited resources.
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  • 文章类型: Journal Article
    背景:老年护理评估小组是澳大利亚老年护理系统的评估组成部分。他们的目的是进行基于需求的评估,以确定老年人的资格,以及获得英联邦资助的老年护理服务。从被评估人的角度来看,没有任何措施可以告诉我们老年护理评估服务是否具有高质量。澳大利亚的老年护理机构已经制定并引入了质量措施。然而,这些,没有考虑过生活在这种环境中的人的观点。还建议了家庭护理服务的质量措施。这项研究旨在通过要求老年护理评估服务的当前和未来服务用户对24个以人为本的质量指标(PC-QI)的重要性进行投票,来解决以人为本的质量指标方面的差距。这是在先前的研究中使用改进的Delphi方法方法开发的,该方法得到了消费者主导的咨询委员会的支持。
    方法:这项混合方法研究使用RAND/UCLA适当性方法就最终的PC-QI集达成共识。布里斯班有25名居住在社区的老年人,澳大利亚,使用五点李克特量表对24个PC-QI的重要性进行了投票。在参与者投票之前,确定了消除PC-QI的共识声明。投票是与参与者面对面或通过电话单独进行的,在他们的家里。要捕获参与者提供的关于每个PC-QI的任何叙述,参与者投票会议被录音,随后被逐字转录。计算每个PC-QI参与者投票的定量数据,并通过中位数进行统计描述,四分位数间距,达成共识,百分位数,百分位排名,等级顺序,中位数和标准差。然后根据消除的共识声明对PC-QI进行评估,并根据对参与者的重要性进行排序。对来自音频转录的定性数据进行内容分析,以确定支持每个PC-QI的参与者投票的某些单词的存在。
    结果:投票期间没有PC-QI被淘汰。参与者对每个PC-QI的重要性评分存在差异。最终质量域,各自的头衔,给出了质量指标描述符和支持定性数据。五个PC-QI的中位数为五个,没有低于4票的记录,四分位数间距为零,排名顺序得分为1,两个和四个,在可能的十个中,表明他们是最重要的参与者。
    结论:参与者就24个基于证据的PC-QIs达成共识,这些PC-QIs代表了从当前和未来服务使用者的角度衡量老年护理评估服务质量的指标。
    在澳大利亚,65岁或以上的人,原住民和托雷斯海峡岛民50岁或以上,可以申请获得澳大利亚政府资助的老年护理服务(澳大利亚政府,卫生和老年护理部门。2021-2022年《1997年老年护理法》运行报告,2022年)。政府资助的服务包括支持老年人在家生活,如果这个人不能住在家里,和短期康复(澳大利亚政府,卫生和老年护理部门。2021-2022年《1997年老年护理法》运行报告,2022年)。要访问这些服务,一个人需要填写申请表并接受老年人护理评估。另一个人可以帮助完成申请。老年护理评估的目的是评估个人的需求,以确定他们有资格获得哪些老年护理服务。从被评估人的角度来看,没有任何措施可以告诉我们老年护理评估服务是否具有高质量。在先前的研究中,在消费者咨询委员会的支持下,制定了24项质量指标(SmithS,TraversC,罗伯茨N,马丁·汗·M·健康预期,2024).这项研究询问了居住在布里斯班的25名老年人,24项措施的重要性,决定是否应该消除。人们被要求使用数字量表进行投票,其中排名第一的意思是“不重要”,五个意味着它“极其重要”。商定了一项协商一致声明,以决定是否取消一项措施。所有措施都被认为是重要的,没有取消任何措施。投票认为重要的质量措施包括接受知识渊博的医护人员的评估,他们以尊严和尊重的态度对待他们,采取以人为本的方法,建立了合作关系,并且沟通清楚。
    BACKGROUND: Aged Care Assessment Teams are the assessment component of the Australian aged care system. Their purpose is to undertake needs-based assessments to determine an older person\'s eligibility for, and access to Commonwealth-funded aged care services. There are no measures that tell us if the aged care assessment service is of high quality from the perspective of the person being assessed. Quality measures have been developed and introduced in Australian residential aged care facilities. These however, have not considered the perspectives of those living in this setting. Quality measures for home care services have also been recommended. This research aims to address the gap in person-centred quality measures by asking current and future service users of aged care assessment services to vote on the importance of 24 person-centred quality indicators (PC-QIs), that were developed in a previous study using a modified Delphi method approach supported by engagement with a consumer led Advisory Board.
    METHODS: This mixed methods study used the RAND/UCLA Appropriateness Method to reach consensus on a final set of PC-QIs. Twenty-five community-dwelling older people in Brisbane, Australia, voted on the importance of 24 PC-QIs using a five-point Likert scale. A consensus statement for PC-QI elimination was determined prior to participants voting. Voting was undertaken with participants individually either face-to-face or via telephone, in their homes. To capture any narrative provided by participants regarding each PC-QI, participant voting sessions were audio-recorded and subsequently transcribed verbatim. Quantitative data from participant votes for each PC-QI were calculated and statistically described by median, interquartile range, consensus met, percentile, percentile rank, rank order, median and standard deviation. PC-QIs were then assessed against the consensus statement for elimination and rank ordered according to importance to participants. Content analysis of qualitative data from audio transcriptions was conducted to determine the presence of certain words supporting participant votes for each PC-QI.
    RESULTS: No PC-QIs were eliminated during voting. Variation existed among participants\' ratings of importance for each PC-QI. Final quality domains, their respective title, quality indicator descriptor and supporting qualitative data are presented. Five PC-QIs had a median of five, no votes recorded below four, an interquartile range of zero, and a rank order score of one, two and four, out of a possible ten, indicating they were of highest importance to participants.
    CONCLUSIONS: Participants reached consensus on 24 evidence-based PC-QIs that represent measures of quality of aged care assessment services from the perspectives of current and future service users.
    In Australia, people 65 years or over, and Aboriginal and Torres Strait Islander Peoples 50 years or over, can apply to access aged care services funded by the Australian government (Australian Government, Department of Health and Aged Care. 2021-2022 Report on the Operation of the Aged Care Act 1997, 2022). Services the government funds include supporting older people to live at home, residential aged care if the person can’t live at home, and short-term rehabilitation (Australian Government, Department of Health and Aged Care. 2021-2022 Report on the Operation of the Aged Care Act 1997, 2022). To access these services, a person needs to fill out an application form and undergo an aged care assessment. Another person can help complete the application. The purpose of the aged care assessment is to assess the person’s needs to determine what aged care services they are eligible to access. There are no measures that tell us if the aged care assessment service is of high quality from the perspective of the person being assessed. Twenty-four measures of quality were developed in a previous study with support from a consumer Advisory Board (Smith S, Travers C, Roberts N, Martin‐Khan M. Health Expect, 2024). This study asked 25 older people living in Brisbane, the importance of the 24 measures, to decide if any should be eliminated. People were asked to vote using a number scale where number one meant it ‘wasn’t important’, and five meant it was ‘extremely important.’ A consensus statement was agreed to decide if a measure would be eliminated. All measures were voted as being important with no measure eliminated. Quality Measures voted as being important included receiving assessments from knowledgeable health care staff, who treated them with dignity and respect, adopted a person-centred approach, established a collaborative relationship, and communicated clearly.
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  • 文章类型: Journal Article
    背景:饮食不仅是生存和健康的基础,还有人类如何组织他们的社交生活。与他人一起吃饭通常被视为健康的理想,虽然单独吃饭被强调为负面健康结果的风险因素,尤其是老年人。这篇论文,因此,调查瑞典70至75岁人群中单独进食的频率和主观体验与食物相关结局之间的关系。
    方法:将一项调查分发给了全国代表性的1500个居住在瑞典的社区的随机样本,70-75岁。测量了两种不同的单独进食结构(客观和主观),以及以下与食物相关的结果:食物指数,食物组的摄入,食用现成的饭菜,每天的主餐数量,体重指数(BMI)。
    结果:总计,最终样本中包括695名受访者。四分之一的受访者被归类为单独吃饭,其中一小部分人报告说这样做困扰了他们。单独进食和食物指数得分之间没有关联,BMI,或者水果和浆果的摄入频率,或者鱼和贝类。然而,单独吃饭的人不太可能报告每天吃三餐(OR:0.53,CI:0.37-0.76,p=0.006),不太可能报告更高的蔬菜和零食摄入频率,含糖食物,和甜饮料(调整后的OR:0.68,CI:0.48-0.95,p=0.023resp。OR:0.59,CI:0.43-0.81,p=0.001),与与其他人一起吃饭的人相比,更有可能报告更高的现成膳食摄入频率(调整后的OR:3.71,CI:2.02-6.84,p<0.001)。单独进食的主观体验对食物相关结果没有影响。
    结论:单独或与他人一起进食在参与者的食物摄入中起作用,并且似乎影响了日常饮食习惯的组织方面,而不是整体饮食健康或体重状况。我们的发现增加了先前关于共情的研究,独自吃饭,老年人群的健康,提供对未来卫生政策和研究发展的见解。
    BACKGROUND: Eating is fundamental not only to survival and health, but also to how humans organise their social lives. Eating together with others is often seen as the healthy ideal, while eating alone is highlighted as a risk factor for negative health outcomes, especially among older adults. This paper, therefore, investigates the relationship between the frequency and subjective experience of eating alone and food-related outcomes among 70- to 75-year-olds in Sweden.
    METHODS: A survey was distributed to a nationally representative random sample of 1500 community-living in Sweden, aged 70-75 years. Two different constructs of eating alone (objective and subjective) were measured, along with the following food-related outcomes: a food index, intake of food groups, consumption of ready-made meals, number of main meals per day, and body mass index (BMI).
    RESULTS: In total, 695 respondents were included in the final sample. A quarter of the respondents were categorised as eating alone, of which a small proportion reported that doing so bothered them. There were no associations between eating alone and food index scores, BMI, or intake frequencies of fruits and berries, or fish and shellfish. However, people eating alone were less likely to report eating three meals per day (OR: 0.53, CI: 0.37-0.76, p = 0.006), less likely to report higher intake frequencies of vegetables and snacks, sugary foods, and sweet drinks (adjusted OR: 0.68, CI: 0.48-0.95, p = 0.023 resp. OR: 0.59, CI: 0.43-0.81, p = 0.001), and more likely to report higher intake frequencies of ready-made meals (adjusted OR: 3.71, CI: 2.02-6.84, p < 0.001) compared to those eating together with others. The subjective experience of eating alone did not have an impact on food-related outcomes.
    CONCLUSIONS: Eating alone or with others played a role in participants\' food intake, and seemed to influence aspects of the organisation of everyday eating routines rather than overall dietary healthiness or weight status. Our findings add to the previous body of research on commensality, eating alone, and health among the older population, providing insights into the development of future health policies and research.
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  • 文章类型: Journal Article
    背景:Molnupiravir和尼马特雷韦-利托那韦口服药物治疗轻度至中度COVID-19。然而,这些药物在非常老(≥80岁)的有效性,住院患者仍不清楚,限制这些抗病毒药物在这一特定组中的风险-收益评估.这项研究调查了这些抗病毒药物在降低该组COVID-19住院患者死亡率方面的有效性。
    方法:使用香港全港公共医疗数据库,我们进行了一项目标试验模拟研究,数据来自于13642名符合资格的molnupiravir试验参与者和9553名nirmatrelvir-ritonavir试验参与者.主要结果是全因死亡率。使用克隆审查加权方法将不朽的时间和混杂的偏见降至最低。通过稳定的逆概率权重调整混杂偏差后,通过汇总逻辑回归估算死亡率比值比。
    结果:莫诺比拉韦(HR:0.895,95%CI:0.826-0.970)和尼马特雷韦-利托那韦(HR:0.804,95%CI:0.678-0.955)均显示年龄最大的住院患者的死亡率风险降低。在口服抗病毒治疗和疫苗接种状态之间没有观察到显著的相互作用。对于两种molnupiravir,发起者的28天死亡风险均低于非发起者(风险差异:-1.09%,95%CI:-2.29,0.11)和尼马特雷韦-利托那韦(风险差异:-1.71%,95%CI:-3.30,-0.16)试验。无论患者先前的疫苗接种状态如何,都观察到这些药物的有效性。
    结论:Molnupiravir和nirmatrelvir-ritonavir在降低住院年龄最大的COVID-19患者的死亡风险方面是中等有效的,无论其疫苗接种状态如何。
    BACKGROUND: Molnupiravir and nirmatrelvir-ritonavir are orally administered pharmacotherapies for mild to moderate COVID-19. However, the effectiveness of these drugs among very old (≥80 years), hospitalised patients remains unclear, limiting the risk-benefit assessment of these antivirals in this specific group. This study investigates the effectiveness of these antivirals in reducing mortality among this group of hospitalised patients with COVID-19.
    METHODS: Using a territory-wide public healthcare database in Hong Kong, a target trial emulation study was conducted with data from 13 642 eligible participants for the molnupiravir trial and 9553 for the nirmatrelvir-ritonavir trial. The primary outcome was all-cause mortality. Immortal time and confounding bias was minimised using cloning-censoring-weighting approach. Mortality odds ratios were estimated by pooled logistic regression after adjusting confounding biases by stabilised inverse probability weights.
    RESULTS: Both molnupiravir (HR: 0.895, 95% CI: 0.826-0.970) and nirmatrelvir-ritonavir (HR: 0.804, 95% CI: 0.678-0.955) demonstrated moderate mortality risk reduction among oldest-old hospitalised patients. No significant interaction was observed between oral antiviral treatment and vaccination status. The 28-day risk of mortality was lower in initiators than non-initiators for both molnupiravir (risk difference: -1.09%, 95% CI: -2.29, 0.11) and nirmatrelvir-ritonavir (risk difference: -1.71%, 95% CI: -3.30, -0.16) trials. The effectiveness of these medications was observed regardless of the patients\' prior vaccination status.
    CONCLUSIONS: Molnupiravir and nirmatrelvir-ritonavir are moderately effective in reducing mortality risk among hospitalised oldest-old patients with COVID-19, regardless of their vaccination status.
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  • 文章类型: Journal Article
    维生素D对肌肉骨骼健康至关重要,补充可能会降低跌倒的风险。过去在住宅老年护理(RAC)环境中关于维生素D对跌倒影响的研究报告没有定论,部分原因是研究设计的局限性。我们利用纵向研究设计来评估在RAC中使用维生素D与36个月内跌倒之间的关联。
    一项纵向队列研究是使用从悉尼27家RAC设施中收集的9年常规电子数据进行的,新南威尔士州,澳大利亚。该研究包括4520名65岁或以上的永久居民,他们从2014年7月1日起首次入院,并停留至少一个月。我们确定了超过36个月的每日维生素D使用量,并使用承保天数(PDC)指标衡量依从性。PDC值≥80%表示最佳依从性。主要结果是所有跌倒和伤害性跌倒的次数。滚动时变预测结果方法和广义估计方程(GEE)用于确定维生素D补充剂使用与随后跌倒风险之间的纵向联系。
    超过三分之二的居民(67.8%;n=3063)在逗留期间接受了维生素D补充剂,用户的PDC中位数为74.8%,44.6%(n=1365)达到最佳依从性。年龄增长,骨质疏松或骨折史,痴呆与获得最佳依从性的可能性更大.所有跌倒和伤害性跌倒的粗跌倒发生率分别为每1000个居民日8.05和2.92。在考虑了相关的人口统计学和临床因素后,维生素D补充剂的使用和跌倒结局之间没有显著联系:所有跌倒(发生率比[IRR]1.01;95%CI1.00-1.02;P=0.237)和伤害性跌倒(IRR1.01;95%CI1.00-1.02;P=0.091).
    补充维生素D与降低跌倒风险无关,这表明它不是预防RAC跌倒的有效干预措施。虽然临床医生应确保足够的维生素D摄入居民的营养和骨骼健康,它不应该是RAC人群中独立的跌倒预防干预措施.
    UNASSIGNED: Vitamin D is vital for musculoskeletal health, and supplementation may lower risk of falls. Past research in residential aged care (RAC) settings on the effects of vitamin D on falls have reported inconclusive findings, partly due to study design limitations. We utilised a longitudinal study design to assess the association between the use of vitamin D and falls over 36 months in RAC.
    UNASSIGNED: A longitudinal cohort study was conducted using routinely collected electronic data spanning 9 years from 27 RAC facilities in Sydney, New South Wales, Australia. The study included 4520 permanent residents aged 65 years or older who were admitted for the first time from 1 July 2014 and stayed for a minimum of one month. We identified daily vitamin D usage over 36 months, and measured adherence using the Proportion of Days Covered (PDC) metric. A PDC value of ≥80 % signifies optimal adherence. Primary outcomes were the number of all falls and injurious falls. A rolling time-varying predictor-outcome approach and Generalized Estimating Equations (GEE) were applied to determine the longitudinal link between vitamin D supplement use and subsequent risk of falls.
    UNASSIGNED: Over two-thirds of residents (67.8 %; n = 3063) received vitamin D supplements during their stay, with a median PDC of 74.8 % among users, and 44.6 % (n = 1365) achieving optimal adherence. Increasing age, osteoporosis or fracture history, and dementia were associated with a greater likelihood of achieving optimal adherence. Crude fall incident rates were 8.05 and 2.92 incidents per 1000 resident days for all falls and injurious falls respectively. After accounting for relevant demographic and clinical factors, no significant links were observed between vitamin D supplement usage and fall outcomes: all falls (Incident Rate Ratio [IRR] 1.01; 95 % CI 1.00-1.02; P = 0.237) and injurious falls (IRR 1.01; 95 % CI 1.00-1.02; P = 0.091).
    UNASSIGNED: Vitamin D supplementation was not associated with a reduced risk of falls, suggesting it is not an effective intervention for preventing falls in RAC. While clinicians should ensure adequate vitamin D intake for residents\' nutritional and bone health, it should not be a standalone falls prevention intervention in RAC populations.
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  • 文章类型: Journal Article
    背景:瑞典社区的一线管理人员有责任为老年人提供护理,人员配置充足,单位预算平衡。由于需要护理的人口不断增长,这是一场资源有限的斗争。这可能导致错过护理。目的是描述一线管理人员对老年人社区医疗保健中错过护理的看法。
    方法:采用现象学方法的定性设计,面试24名一线经理。该研究的伦理批准来自卡尔斯塔德大学的研究伦理委员会(DnrHNT2020/566)。
    结果:结果显示在包含15种感知的六个描述性类别中。描述性类别是“错过护理的发生”,\'意识到错过的护理\',\'错过护理的原因\',“错过护理对老年人有影响”,“错过的护理对工作人员有影响”和“采取行动减少错过的护理”。
    结论:一线管理人员必须意识到错过护理的存在和原因,因为它对老年人和工作人员有影响。管理人员需要认真对待错过的护理,以便进行改进,以保持良好的护理质量和患者安全。
    BACKGROUND: First-line managers in Swedish communities have responsibility for that care to older people is provided, staffing is sufficient and the budget is balanced in their unit. It is a struggle with limited resources due to a growing population in need of care. This can lead to missed nursing care. The aim was to describe first-line managers´ perceptions of missed nursing care in community health care for older people.
    METHODS: A qualitative design with a phenomenographic approach, interviewing 24 first-line managers. Ethics approval for the study was received from the Research Ethics Committee at Karlstad University (Dnr HNT 2020/566).
    RESULTS: The results are shown in six descriptive categories containing 15 perceptions. The descriptive categories are \'occurrence of missed nursing care\', \'becoming aware of missed nursing care\', \'reasons for missed nursing care\', \'missed nursing care has consequences for the older persons\', \'missed nursing care has consequences for the staff\' and \'taking action to decrease missed nursing care\'.
    CONCLUSIONS: It is important for first-line managers to become aware of the existence and reasons for missed nursing, as it has consequences for older people and staff. Managers need to take missed nursing care seriously in order to work with improvements for maintaining good quality of care and patient safety.
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  • 文章类型: Journal Article
    背景:在老龄化社会中,管理老年骨科患者的药物使用对于延长他们的健康预期寿命至关重要。然而,关于复方制剂的实际情况,摄入潜在的不适当药物(PIMs),老年骨科患者的跌倒风险增加药物(FRID)的特征不明确。这项研究旨在调查老年骨科患者的药物治疗概况,以突出关注的关键点。
    方法:我们回顾性回顾了2020年4月至2021年3月在两家急诊医院接受骨科手术的年龄≥65岁的连续患者的临床资料。多重用药的处方药的截止数量设定为6。根据指定的指导方针,19种药物被确定为PIMs,和10个类别被归类为FRID。
    结果:共评估了995名骨科手术的老年患者,其中57.4%被诊断为多重用药,66.0%的人接受了PIMs,41.7%的人接受FRID。在患有退行性脊柱疾病的患者中,FRID摄入的患病率没有显着差异(n=316),四肢退行性疾病(n=331),和骨折(n=272)。与四肢退行性疾病患者相比,在退行性脊柱疾病患者中,多重用药和PIM摄入量的多变量校正患病率(PR)明显更高(1.26[置信区间(CI):1.11-1.44]和1.12[CI:1.00-1.25]),分别。使用止吐药(调整后的PR,13.36;95%CI:3.14-56.81)和非甾体抗炎药(调整后的PR,1.37;95%CI:1.05-1.78)显著高于退行性脊柱疾病患者。在患有退行性脊柱疾病的患者中,腰椎患者服用止吐药的患病率为8.7%,颈椎患者为0%。
    结论:本研究中超过一半的骨科患者受到多重用药的影响,与其他骨科疾病相比,大约三分之二的患者服用了某种形式的PIM。患有退行性脊柱疾病的患者显示出更高的多药和PIM使用率。在腰椎退行性疾病患者中,应特别注意止吐药和非甾体抗炎药的摄入频率较高。
    BACKGROUND: Managing medication use in older orthopedic patients is imperative to extend their healthy life expectancy in an aging society. However, the actual situation regarding polypharmacy, the intake of potentially inappropriate medications (PIMs), and fall risk-increasing drugs (FRIDs) among older orthopedic patients is not well characterized. This study aimed to investigate the medication-based profiles of older orthopedic patients to highlight the critical points of concern.
    METHODS: We retrospectively reviewed the clinical data of consecutive patients aged ≥ 65 years who underwent orthopedic surgery at two acute care hospitals between April 2020 and March 2021. The cutoff number of prescribed drugs for polypharmacy was set at 6. According to the specified guidelines, 19 categories of drugs were identified as PIMs, and 10 categories were classified as FRIDs.
    RESULTS: A total of 995 older patients with orthopedic surgery were assessed, of which 57.4% were diagnosed with polypharmacy, 66.0% were receiving PIMs, and 41.7% were receiving FRIDs. The prevalence of FRID intake did not significantly differ among patients with degenerative spinal disease (n = 316), degenerative disease of extremities (n = 331), and fractures (n = 272). Compared with patients with degenerative disease of the extremities, the multivariable-adjusted prevalence ratios (PRs) of polypharmacy and PIM intake were significantly higher in patients with degenerative spinal disease (1.26 [confidence intervals (CI): 1.11-1.44] and 1.12 [CI: 1.00-1.25]), respectively. Use of antiemetic drugs (adjusted PR, 13.36; 95% CI: 3.14-56.81) and nonsteroidal anti-inflammatory drugs (adjusted PR, 1.37; 95% CI: 1.05-1.78) was significantly higher in patients with degenerative spinal disease. Among patients with degenerative spinal disease, the prevalence of antiemetic drug intake was 8.7% in lumbar spinal patients and 0% in cervical spinal patients.
    CONCLUSIONS: More than half of the orthopedic patients in this study were affected by polypharmacy, and approximately two-thirds were prescribed some form of PIMs. Patients with degenerative spinal disease showed a significantly higher prevalence of polypharmacy and PIM use compared with other orthopedic diseases. Particular attention should be paid to the high frequency of antiemetic drugs and nonsteroidal anti-inflammatory drugs intake among patients with degenerative lumbar spine conditions.
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  • 文章类型: Journal Article
    背景:由于急诊科(ED)中虚弱的老年患者数量不断增加,认知障碍和多重性,需要在ED中的老年医学专业知识。
    方法:这项回顾性研究是针对2022年1月2日至12月31日在图尔库大学医院ED就诊的老年患者。使用分类风险筛查工具(TRST)和临床虚弱量表(CFS)对75岁以上的患者进行虚弱筛查。非急性,体弱的患者(CFS≥4)适合针对性老年评估(TGA)(n=1096)进行了谵妄风险扫描,认知障碍,功能状态的变化,falls,营养不良和抑郁症。进行了全面的患者记录,并提出了未来护理的建议。
    结果:TRST在70%的急诊就诊中完成,其中三分之二被认为是高风险的。在老年团队(TGA)评估的患者中,非特异性投诉(38%)和跌倒(35%)是ED入院的主要原因.超过60%的患者存在认知障碍,而40%的患者存在直立性低血压。TGA患者的72小时再就诊率为2.3%。对于现实生活中的控制组,72小时复诊率为4.6%(P=.001).三十天重访率分别为10%和16%,分别(P<.001)。康复的需要,认知评估和强化家庭护理是未来护理的主要建议.
    结论:TGA方法提供了关于老年患者背景的结构化和准确的信息。这可能会导致更精确的诊断,彻底考虑医院的摄入量和急诊室的安全出院。确保护理的连续性可能有助于减少ED的再入院。
    BACKGROUND: Due to the increasing number of older patients in emergency departments (EDs) with frailty, cognitive impairment and multimorbidity, there is a need for geriatric expertise in EDs.
    METHODS: This retrospective study is of older patients visiting Turku University Hospital ED between 2 January and 31 December 2022. Patients aged 75 years of older were screened for frailty using Triage Risk Screening Tool (TRST) and Clinical Frailty Scale (CFS). Nonacute, frail patients (CFS ≥4) suitable for Targeted Geriatric Assessment (TGA) (n = 1096) were scanned for the risk of delirium, cognitive impairment, change in functional status, falls, malnutrition and depression. A comprehensive patient record was made with recommendations for future care.
    RESULTS: TRST was completed in 70% of the ED visits, and two-thirds of those were considered high-risk. Among the patients assessed by the geriatric team (TGA), nonspecific complaint (38%) and falls (35%) were the main reasons for ED admission. Cognitive impairment was present in over 60% and orthostatic hypotension in 40% of the patients. The 72-hour revisit rate for TGA-patients was 2.3%. For the real-life control group, the 72-hour revisit rate was 4.6% (P = .001). Thirty-day revisit rates were 10% and 16%, respectively (P < .001). The need for rehabilitation, cognitive evaluation and intensifying home care were the main recommendations for future care.
    CONCLUSIONS: TGA approach provides structured and accurate information on older patients\' background. This may lead to more precise diagnostics, a thorough consideration of hospital intake and a secure discharge from the ED. Ensuring continuity of care may help to reduce readmissions to EDs.
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  • 文章类型: Journal Article
    背景:我们旨在研究OA与痴呆风险和脑结构异常的治疗之间的关联。
    方法:我们从英国生物银行招募了466,460名个体,以调查OA对痴呆发病率的影响。在总人口中,有63,081名参与者被诊断为OA.随后,我们根据治疗途径将OA患者分为药物和手术组。Cox回归模型探讨了OA/OA治疗与痴呆风险之间的关系,结果表示为风险比(HR)和95%置信区间(95%CI)。线性回归模型评估了OA/OA治疗与皮质结构改变的关联。
    结果:在平均11.90(±1.01)年的随访中,5627人被诊断为全因痴呆(ACD),包括2,438AD(阿尔茨海默病),1,312例VaD(血管性痴呆)病例。结果显示,OA与ACD(HR:1.116;95%CI:1.039-1.199)和AD(HR:1.127;95%CI:1.013-1.254)的风险升高相关。在药物治疗组(HR:0.746;95%CI:0.652-0.854)和手术组(HR:0.841;95%CI:0.736-0.960)中,OA治疗均降低了痴呆的风险。OA与皮质面积呈负相关,尤其是前中央,后中部和时间区域。
    结论:骨关节炎增加了患痴呆的可能性,并与局部脑萎缩有关。OA治疗降低了痴呆的风险。OA是痴呆的有希望的可改变的危险因素。
    BACKGROUND: We aimed to investigate the association between OA and treatment with dementia risk and structural brain abnormalities.
    METHODS: We recruited a total of 466,460 individuals from the UK Biobank to investigate the impact of OA on the incidence of dementia. Among the total population, there were 63,081 participants diagnosed with OA. We subsequently categorised the OA patients into medication and surgery groups based on treatment routes. Cox regression models explored the associations between OA/OA treatment and dementia risk, with the results represented as hazard ratios (HRs) and 95% confidence intervals (95% CI). Linear regression models assessed the associations of OA/OA therapy with alterations in cortical structure.
    RESULTS: During an average of 11.90 (± 1.01) years of follow-up, 5,627 individuals were diagnosed with all-cause dementia (ACD), including 2,438 AD (Alzheimer\'s disease), and 1,312 VaD (vascular dementia) cases. Results revealed that OA was associated with the elevated risk of ACD (HR: 1.116; 95% CI: 1.039-1.199) and AD (HR: 1.127; 95% CI: 1.013-1.254). OA therapy lowered the risk of dementia in both medication group (HR: 0.746; 95% CI: 0.652-0.854) and surgery group (HR: 0.841; 95% CI: 0.736-0.960). OA was negatively associated with cortical area, especially precentral, postcentral and temporal regions.
    CONCLUSIONS: Osteoarthritis increased the likelihood of developing dementia, and had an association with regional brain atrophy. OA treatment lowered the dementia risk. OA is a promising modifiable risk factor for dementia.
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  • 文章类型: Journal Article
    背景:许多老年人同时患有多种长期疾病和虚弱;因此,他们管理复杂的药物治疗方案,并且面临药物错误后果的风险更高。加强人们如何管理药物的研究侧重于坚持治疗方案,而不是安全管理药物所需的更广泛的技能。和老年人口生活虚弱和管理多种药物在家里一直在探索。这项研究,因此,深入研究轻度至中度虚弱的老年人如何在家中管理他们的多药房治疗方案。
    方法:在2021年6月至2022年2月之间,从英格兰北部的10个医疗实践中招募了32名年龄在65岁或以上的轻度或中度虚弱并服用5种或更多药物的患者,英国,和CARE75+研究队列。进行了面对面的半结构化访谈,通过电话或在线。采访被记录下来,逐字转录,并使用反身主题分析进行分析。
    结果:开发了五个主题:(1)管理许多药物是我没有申请的熟练工作;(2)药物使我继续前进,但是我的生活发生了什么?(3)在一个不清楚的系统中管理药物;(4)支持使我的工作更轻松的药物;(5)我的药物对我来说是熟悉的-没有其他我需要(或想)知道的东西。在导航支离破碎的护理时,预计患者将适应新的常规药物进入他们的生活,并保持他们的药物供应。有时候,他们感到失望的系统,创造了新的障碍,而不是支持他们复杂的日常工作。
    结论:虚弱的老年患者,他们面临药物错误影响的风险更高,预计将执行复杂的工作,以安全地自我管理多种药物在家里。这样的工作量需要得到承认,需要做更多的工作来准备人们,以避免药物的伤害。
    一位在家中管理多种药物的老年人是研究团队的核心成员。一个由老年患者和家庭成员组成的咨询小组为这项研究提供了建议,并参与了数据分析的第一阶段。这影响了数据的编码和主题的形成。
    BACKGROUND: Many older people live with both multiple long-term conditions and frailty; thus, they manage complex medicines regimens and are at heightened risk of the consequences of medicines errors. Research to enhance how people manage medicines has focused on adherence to regimens rather than on the wider skills necessary to safely manage medicines, and the older population living with frailty and managing multiple medicines at home has been under-explored. This study, therefore, examines in depth how older people with mild to moderate frailty manage their polypharmacy regimens at home.
    METHODS: Between June 2021 and February 2022, 32 patients aged 65 years or older with mild or moderate frailty and taking five or more medicines were recruited from 10 medical practices in the North of England, United Kingdom, and the CARE 75+ research cohort. Semi-structured interviews were conducted face to face, by telephone or online. The interviews were recorded, transcribed verbatim and analysed using reflexive thematic analysis.
    RESULTS: Five themes were developed: (1) Managing many medicines is a skilled job I didn\'t apply for; (2) Medicines keep me going, but what happened to my life?; (3) Managing medicines in an unclear system; (4) Support with medicines that makes my work easier; and (5) My medicines are familiar to me-there is nothing else I need (or want) to know. While navigating fragmented care, patients were expected to fit new medicines routines into their lives and keep on top of their medicines supply. Sometimes, they felt let down by a system that created new obstacles instead of supporting their complex daily work.
    CONCLUSIONS: Frail older patients, who are at heightened risk of the impact of medicines errors, are expected to perform complex work to safely self-manage multiple medicines at home. Such a workload needs to be acknowledged, and more needs to be done to prepare people in order to avoid harm from medicines.
    UNASSIGNED: An older person managing multiple medicines at home was a core member of the research team. An advisory group of older patients and family members advised the study and was involved in the first stages of data analysis. This influenced how data were coded and themes shaped.
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