癌症是全球死亡的主要原因,需要不断改进诊断和治疗。传统方法往往缺乏敏感性和特异性,导致需要新的方法。3D打印已经成为癌症诊断的变革性工具,提供精确和可定制的纳米传感器的潜力。这些进步在癌症研究中至关重要,旨在提高肿瘤的早期检测和监测。在当前时代,3D打印技术作为一种灵活的介质,用于生产具有出色灵敏度和特异性的精确和适应性纳米传感器。该研究旨在通过使用3D打印技术开发先进的3D打印纳米传感器来增强癌症的早期诊断和预后。该研究探索了各种3D打印技术,设计策略,和癌症特异性生物标志物的功能化策略。这些纳米传感器与荧光等检测模式的集成,电化学,和表面增强拉曼光谱也进行了评估。这项研究探讨了喷墨打印的使用,立体光刻,和熔融沉积建模,以创建具有增强性能的纳米结构。它还讨论了针对癌症指标的设计和功能化方法。3D打印纳米传感器与多种检测方式的集成,包括荧光,电化学,和表面增强拉曼光谱,实现快速可靠的癌症诊断。结果显示提高了对癌症生物标志物的敏感性和特异性,能够早期检测肿瘤指标和循环细胞。该研究强调了3D打印纳米传感器通过实现对肿瘤生物标志物的高灵敏度和特异性检测来改变癌症诊断的潜力。它标志着癌症诊断的关键一步,展示了3D打印技术生产先进纳米传感器的能力,这些传感器可以显着改善早期癌症检测和患者预后。
Cancer is the leading cause of mortality worldwide, requiring continuous advancements in diagnosis and treatment. Traditional methods often lack sensitivity and specificity, leading to the need for new methods. 3D printing has emerged as a transformative tool in cancer diagnosis, offering the potential for precise and customizable nanosensors. These advancements are critical in cancer research, aiming to improve early detection and monitoring of tumors. In current times, the usage of the 3D printing technique has been more prevalent as a flexible medium for the production of accurate and adaptable nanosensors characterized by exceptional sensitivity and specificity. The study aims to enhance early cancer diagnosis and prognosis by developing advanced 3D-printed nanosensors using 3D printing technology. The research explores various 3D printing techniques, design strategies, and functionalization strategies for cancer-specific biomarkers. The integration of these nanosensors with detection modalities like fluorescence, electrochemical, and surface-enhanced Raman spectroscopy is also evaluated. The study explores the use of inkjet printing, stereolithography, and fused deposition modeling to create nanostructures with enhanced performance. It also discusses the design and functionalization methods for targeting cancer indicators. The integration of 3D-printed nanosensors with multiple detection modalities, including fluorescence, electrochemical, and surface-enhanced Raman spectroscopy, enables rapid and reliable cancer diagnosis. The results show improved sensitivity and specificity for cancer biomarkers, enabling early detection of tumor indicators and circulating cells. The study highlights the potential of 3D-printed nanosensors to transform cancer diagnosis by enabling highly sensitive and specific detection of tumor biomarkers. It signifies a pivotal step forward in cancer diagnostics, showcasing the capacity of 3D printing technology to produce advanced nanosensors that can significantly improve early cancer detection and patient outcomes.