Abstract：
The incidence of thyroid tumors has been increasing yearly over the past decade, making it the fourth highest tumor in women. This places various biological burdens on those affected. Currently, thyroid tumors are primarily diagnosed using percutaneous fine needle aspiration and ultrasound. However, these methods are complex, expensive, and less accurate, and they may fail to detect some thyroid nodules. As an alternative, researchers are focusing on blood-based biomarkers in addition to the traditional diagnostic methods, assisted predominantly by nanomaterials. Early identification of thyroid cancer is crucial as it is highly treatable. Various sensing systems have been developed using nanomaterial-mediated approaches to enhance the detection system. Nanomaterials are effectively applied in biosensors for surface functionalization and are conjugated with biomolecules to improve the interaction with the target analyte. This review discusses nanomaterial-assisted thyroid tumor detection, with a special focus on nanomaterial-based biosensors.
摘要：
在过去的十年中，甲状腺肿瘤的发病率逐年增加，使其成为女性第四大肿瘤。这给受影响的人带来了各种生物负担。目前,甲状腺肿瘤主要通过经皮细针穿刺和超声诊断。然而,这些方法很复杂，贵,更不准确，他们可能无法检测到一些甲状腺结节。作为替代,除了传统的诊断方法，研究人员还专注于血液生物标志物，主要由纳米材料协助。早期识别甲状腺癌至关重要，因为它是高度可治疗的。已经使用纳米材料介导的方法开发了各种感测系统以增强检测系统。纳米材料有效地应用于用于表面功能化的生物传感器中，并与生物分子缀合以改善与目标分析物的相互作用。本文综述了纳米材料辅助甲状腺肿瘤的检测，特别关注基于纳米材料的生物传感器。
