微塑料和纳米塑料(MNPs)是一种普遍的环境污染物,引起人们对人类潜在健康影响的重大担忧。这些微小的塑料颗粒已经在各种环境矩阵中被检测到,包括空气,水,土壤,和食物来源。虽然MNPs对野生动物和生态系统的不利影响有据可查,了解它们对人类健康的影响仍处于起步阶段。本研究旨在全面审查记录与MNPs暴露相关的不良健康结果的现有病例报告。通过广泛的文献检索,相关文章进行了识别和分析。MNPs暴露主要通过摄入和吸入途径发生。对消化系统的健康影响包括氧化应激,炎症,生态失调,和代谢紊乱,与MNPs暴露与胃肠道损伤和肝功能障碍相关的病例。呼吸系统的影响包括哮喘加重和过敏性肺炎,特别是在涉及塑料生产的行业。MNPs暴露也与神经系统疾病有关,生殖毒性,骨骼系统干扰,排泄系统破坏,和心血管发病率和死亡率。尽管病例报告有限,MNPs的广泛存在需要进一步调查其潜在的健康风险.这项研究强调了理解和减轻MNPs暴露对健康的不利影响的紧迫性。为了全面评估和解决与环境中MNPs污染相关的危险,进一步的研究势在必行。
Microplastics and
nanoplastics (MNPs) represent a pervasive environmental pollutant, raising significant concerns about potential health effects on humans. These tiny plastic particles have been detected across various environmental matrices, including air, water, soil, and food sources. While the adverse impacts of MNPs on wildlife and ecosystems are well-documented, understanding their effects on human health is still in its infancy. This study aims to comprehensively review existing
case reports documenting adverse health outcomes associated with MNPs exposure. Through an extensive literature search, relevant articles were identified and analyzed. MNPs exposure primarily occurs through ingestion and inhalation routes. Health effects on the digestive system include oxidative stress, inflammation, dysbiosis, and metabolic disorders, with cases linking MNPs exposure to gastrointestinal injury and liver dysfunction. Respiratory system impacts include asthma exacerbation and hypersensitivity pneumonitis, particularly in industries involving plastic production. MNPs exposure has also been associated with nervous system conditions, reproductive toxicity, skeletal system interference, excretory system disruption, and cardiovascular morbidity and mortality. Despite limited
case reports, the widespread presence of MNPs warrants further investigation into their potential health risks. This study underscores the urgency of understanding and mitigating the adverse health effects posed by MNPs exposure. Further research is imperative in order to comprehensively assess and address the dangers associated with MNPs contamination in the environment.