背景:获得性纤维角化瘤(ADFK)是一种罕见的良性纤维上皮瘤,这在中国很少报道。
目的:从当前病例中分析中国人ADFK的临床特征。
方法:从2019年12月至2021年10月,有21例诊断为ADFK,我们对其皮损的临床特点进行了回顾性分析。总结临床形态学,location,和ADFK的手术随访。
结果:我们得出结论,ADFK在女性比男性更常见(7:3),而男女比例在脚上基本相同(6:5)。它更频繁地发生在第三手指(60%)和第一脚趾(45.5%)。至于临床形态学,它通常是杆状的(52.4%),其次是圆顶形(42.8%)和疣形(4.8%)。它通常在手上呈圆顶形(80%),在脚上呈杆状(81.8%)。就手指(脚趾)上的位置而言,这种皮肤病变最常见于近端指甲褶皱(52.4%),这也可以发生在指甲基质(14.3%),甲周面积(23.8%),和甲下面积(9.5%)。然而,这个比例在手和脚上也有所不同。所有患者均行手术切除皮肤损伤,随访6-12个月,没有复发。
结论:大多数ADFK与创伤有关,其临床特征与位置和性别有关。在手指(脚趾)的临床形态和位置上,手上的ADFK与脚上的ADFK不同,手术治疗这种情况是有效的。
BACKGROUND: Acquired digital fibrokeratoma (ADFK) is an uncommon benign fibro-epithelioma, which is rarely reported in China.
OBJECTIVE: To analysis the clinical features of ADFK in Chinese people from current cases.
METHODS: From December 2019 to October 2021, there were 21 patients diagnosed with ADFK, we made a retrospective analysis on the clinical features of skin lesions in them. To summarize the clinical morphology, location, and surgical follow-up of ADFK.
RESULTS: We concluded that ADFK is more common in females than males on the hands (7:3), while the male-to-female ratio is largely the same in feet (6:5). It occurs more frequently on the third finger (60%) and first toe (45.5%). As to clinical morphology, it is typically rod-shaped (52.4%), followed by dome-shaped (42.8%) and wart-shaped (4.8%). It is typically dome-shaped on the hands (80%) and rod-shaped on the feet (81.8%). In terms of location on the fingers (toes), such skin lesions are most common at the proximal nail fold (52.4%), which can also occur at the nail matrix (14.3%), periungual area (23.8%), and subungual area (9.5%). Nevertheless, this ratio also varies on the hands and feet. All patients got surgical excision of the skin lesion, who were followed up for 6-12 months, without recurrence.
CONCLUSIONS: Most ADFKs are associated with trauma, whose clinical features are related to location and gender. ADFKs on the hands are different from those on the feet regarding clinical morphology and location on fingers (toes), and surgery is effective in treating this condition.