牙本质瘤是指甲基质的原发性良性肿瘤。目前,报告的病例数量有限,所以它仍然被认为是一种罕见的肿瘤。然而,如果这种情况被诊断不足和报道不足,这是值得商榷的。甲癣是甲癣的重要鉴别诊断,有时,这两种情况甚至可能共存于同一指甲中。随着肿瘤的生长,组织微环境更容易受到皮肤癣菌的影响。可能,改变的角蛋白似乎易受真菌侵袭。仔细的临床评估和皮肤镜评估有助于确定诊断。通常,当它们共存时,完全指甲撕脱是首选的治疗方法。在这里,我们介绍了一例患有甲癣和甲癣的中年妇女,影响了单个指甲。建议的治疗方法是口服特比萘芬6个月,然后进行保守手术。真菌治疗后,皮肤镜特征发生了戏剧性的变化,which,根据我们的知识,以前没有报道过。
Onychomatricoma is a primary benign neoplasm of the nail matrix. Currently, a limited number of cases have been reported, so it is still considered a rare neoplasia. However, it is debatable if this condition is underdiagnosed and underreported. Onychomycosis is an important differential diagnosis of onychomatricoma, and sometimes, both these conditions may even coexist in the same nail. As the tumor grows, tissue microenvironment is more vulnerable to dermatophytes. Probably, the altered keratin appears to be susceptible to fungal invasion. Careful clinical assessment and dermoscopic evaluation help nailing the diagnosis. Usually, total nail avulsion is the preferred therapeutic approach when they coexist. Herein, we present a
case of a middle-aged woman with onychomycosis and onychomatricoma affecting a single fingernail. The proposed therapy was oral terbinafine for 6 months followed by a conservative surgery. There were dramatic changes in dermoscopic features after fungal treatment, which, to our knowledge, have not been previously reported.