mental illness

精神疾病
  • 文章类型: Journal Article
    在美国,四分之一的女性和11%的男性报告是亲密伴侣暴力(IPV)的幸存者。尽管自己也是受害者,杀死IPV滥用者的人仍然可能受到刑事诉讼。鉴于这种复杂性,法律采用受虐配偶综合征(BSS)作为一些司法管辖区使用的工具来支持IPV幸存者在自卫中丧生的说法.试图使用BSS进行自卫的被告可能会提供创伤后应激障碍(PTSD)的证词。然而,创伤后应激障碍的诊断可能会在诉讼期间给入院带来问题,因为创伤事件的发生通常是正在决定的。本研究调查了大学生,生活在美国-墨西哥边境,在BSS模拟审判中感知幸存者转变为被告。具体来说,我们让每位参与者阅读一份模拟试验的书面试验记录,其中操纵了被告的性别和PTSD的临床诊断.当前的研究假设陪审员对女性被告比男性被告更宽容(假设1),陪审员会受到被告创伤后应激障碍诊断的影响(假设2a-b),女性陪审员会比男性陪审员更宽松(假设3)。我们还想研究受害者指责的影响,性别歧视,创伤后应激障碍的耻辱,以及在决策时事先暴露于IPV(假设4a-d)。调查结果显示,陪审员对女性被告比男性被告更宽容,然而,除了决策困难外,临床诊断没有影响。讨论了被告性别在决策中的作用。
    A quarter of women and 11% of men report being survivors of intimate partner violence (IPV) during their lifetimes in the United States. Despite being victims themselves, people who kill their IPV abuser can still be subject to criminal proceedings. Given this complexity, the law has employed battered spouse syndrome (BSS) as a tool used in some jurisdictions to support a claim that an IPV survivor killed in self-defense. A defendant who is attempting to claim self-defense using BSS may introduce testimony of post-traumatic stress disorder (PTSD). However, a diagnosis of PTSD can pose problems in admission during litigation as the occurrence of a traumatic event is often what is being decided. The present study examined how college students, living on the U.S.-México border, perceive survivors-turned-defendants in a BSS mock trial. Specifically, we had each participant read a written trial transcript of a mock trial where gender of the defendant and clinical diagnosis of PTSD were manipulated. The current study hypothesized that jurors would be more lenient toward female defendants than male defendants (Hypothesis 1), jurors would be influenced by a PTSD diagnosis of the defendant (Hypothesis 2a-b), and female jurors would be more lenient than male jurors (Hypothesis 3). We also wanted to examine the impact of victim blaming, sexism, stigma of PTSD, and prior exposure to IPV on decision-making (Hypothesis 4a-d). Findings showed jurors were more lenient with female defendants than male defendants, however there was no effect of clinical diagnosis except on difficulty of decision. Implications of the role defendant gender has in decision-making is discussed.
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  • 文章类型: Journal Article
    背景:从美沙酮中诱导丁丙诺啡传统上涉及最初的阿片类药物戒断,严重精神疾病(SMI)患者存在精神状态恶化的风险。丁丙诺啡微量给药,小剂量递增,是一种从美沙酮过渡的新型标签外方法,不需要一段时间的美沙酮戒断。鉴于关于丁丙诺啡微量给药的文献有限,我们的目的是评估在一系列接受美沙酮联合SMI的患者中诱导丁丙诺啡的可行性和安全性。
    方法:对于这个回顾性病例系列,我们回顾了墨尔本成瘾治疗中心16名SMI患者的记录,从2021年1月到2022年7月,他们通过微剂量过渡,从高剂量美沙酮(>30mg)到丁丙诺啡和长效丁丙诺啡。精神病诊断,精神状态,其他物质撤出,转让成功,过渡时间,通过客观和主观报告收集阿片类药物戒断症状和总体患者体验。
    结果:88%的患者完成了美沙酮向丁丙诺啡的转移。除轻度增加的焦虑外,心理健康措施保持稳定。住院患者的中位转院时间为6.5天,混合设置9天,门诊患者10天。大多数患者(93%)认为他们的经历“可管理”报告轻度戒断症状。一名患者符合沉淀戒断的研究标准。
    结论:本回顾性病例系列提供了证据,证明使用微量剂量丁丙诺啡诱导美沙酮向丁丙诺啡的转变,包括仓库-丁丙诺啡,风险可以忽略不计,SMI患者可以耐受,并且不太可能加剧他们的精神疾病。
    BACKGROUND: Inducting buprenorphine from methadone has traditionally involved initial opioid withdrawal, with risk of mental state deterioration in patients with serious mental illness (SMI). Micro-dosing of buprenorphine, with small incremental doses, is a novel off-label approach to transitioning from methadone and does not require a period of methadone abstinence. Given the limited literature about buprenorphine microdosing, we aimed to evaluate the feasibility and safety of inducting buprenorphine in a series of patients on methadone with SMI.
    METHODS: For this retrospective case series, we reviewed the records of 16 patients with SMI at a Melbourne addiction treatment centre, from January 2021 to July 2022, who transitioned via micro-dosing, from high-dose methadone (>30 mg) to buprenorphine and depot-buprenorphine. Psychiatric diagnoses, mental state, other substance withdrawal, transfer success, transition time, opioid withdrawal symptoms and overall patient experience were collected via objective and subjective reporting.
    RESULTS: Methadone to buprenorphine transfer was completed by 88% of patients. Mental health measures remained stable with the exception of mildly increased anxiety. Median transfer time was 6.5 days for inpatients, 9 days for mixed setting and 10 days for outpatients. Most patients (93%) rated their experience \'manageable\' reporting mild withdrawal symptoms. One patient met study criteria for precipitated withdrawal.
    CONCLUSIONS: This retrospective case series provides evidence that the use of a micro-dosing buprenorphine induction for methadone to buprenorphine transitions, including to depot-buprenorphine, has negligible risk, is tolerated by patients with SMI and is unlikely to precipitate an exacerbation of their mental illness.
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  • 文章类型: Journal Article
    精神疾病患者的静脉血栓栓塞风险尚未得到充分解决。本研究旨在评估该人群中高同型半胱氨酸血症与静脉血栓栓塞患病率之间的相关性。
    诊断为精神疾病并并发静脉血栓栓塞的患者,2014年1月至2021年12月期间入住浙江大学医学院附属邵逸夫医院,纳入静脉血栓栓塞组。对照组,大约两倍的大小,包括患有精神疾病但没有静脉血栓栓塞的个体。收集两个队列的基本临床数据。
    在精神病患者中,D-二聚体水平升高(OR=5.60,95%CI3.28-10.00),高同型半胱氨酸血症(OR=2.37,95%CI1.10-5.14),高泌乳素血症(OR=2.68,95%CI1.12~6.42)是静脉血栓栓塞的重要危险因素。根据进一步的亚组分析,高同型半胱氨酸血症是肺栓塞的重要危险因素,OR为5.08(95%CI1.20-21.48)。发现性别与同型半胱氨酸水平之间存在交互作用,p相互作用为0.022。随后的分析证实了女性精神病患者高同型半胱氨酸血症和静脉血栓栓塞之间的关联。OR为3.34(95%CI1.68-6.65),表明高同型半胱氨酸血症是女性静脉血栓栓塞的重要危险因素。
    患有精神疾病的患者静脉血栓栓塞的风险升高,这与D-二聚体水平升高有关,高催乳素血症,高同型半胱氨酸血症.在患有精神疾病的患者中,高同型半胱氨酸血症与肺栓塞之间存在很强的相关性。此外,研究显示,患有高同型半胱氨酸血症的女性精神病患者是静脉血栓栓塞症的高危人群.这一发现具有重要的临床意义,提示可对该高危人群实施早期预防措施,以降低精神病患者住院期间血栓栓塞事件的发生率.
    UNASSIGNED: The risk of venous thromboembolism in patients with mental illness has been insufficiently addressed. This study aimed to assess the correlation between hyperhomocysteinemia and venous thromboembolism prevalence among this population.
    UNASSIGNED: Patients with a diagnosis of mental illness and concurrent venous thromboembolism, admitted to Sir Run Run Shaw Hospital at Zhejiang University School of Medicine between January 2014 and December 2021, were included in the venous thromboembolism group. The control group, approximately twice the size, comprised individuals with mental illness but without venous thromboembolism. Basic clinical data were gathered for both cohorts.
    UNASSIGNED: In psychiatric patients, elevated D-dimer levels(OR=5.60,95% CI 3.28-10.00), hyperhomocysteinemia (OR=2.37,95% CI 1.10-5.14), and hyperprolactinemia(OR= 2.68,95% CI 1.12-6.42)were significant risk factors for venous thromboembolism. According to further subgroup analyses, hyperhomocysteinemia is a significant risk factor associated with pulmonary embolism, with an OR of 5.08 (95% CI 1.20-21.48). An interaction effect between gender and homocysteine level was found, with a p-interaction of 0.022. A subsequent analysis confirmed the association between hyperhomocysteinemia and venous thromboembolism in female psychiatric patients, with an OR of 3.34 (95% CI 1.68-6.65), indicating that hyperhomocysteinemia is a significant risk factor for venous thromboembolism in women.
    UNASSIGNED: Patients with psychiatric disorders were found to have an elevated risk of venous thromboembolism, which was associated with increased levels of D-dimer, hyperprolactinemia, and hyperhomocysteinemia. A strong correlation between hyperhomocysteinemia and pulmonary embolism was identified in patients with mental illnesses. Furthermore, the study revealed that female psychiatric patients with hyperhomocysteinemia constituted a high-risk group for venous thromboembolism. This finding holds significant clinical implications, suggesting that early preventative measures could be implemented for this high-risk population to reduce the incidence of thromboembolic events during hospitalization for psychiatric patients.
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  • 文章类型: Journal Article
    2022年12月,ChristopherClunis的死亡被公之于众。他实际上是在2021年2月去世的。ChristopherClunis被判犯有过失杀人罪,乔纳森·齐托.他在火车站袭击了齐托先生。本文将认为,这一可怕的事件成为社区护理政策更广泛失败的象征。Clunis被赶出法院的形象在报纸和其他媒体报道中被反复用作参考点。该图像反映了“精神病患者”的代表中的许多长期存在的特征。“这些与黑人的种族刻板印象相结合。本文研究了精神病患者的历史表现,以此作为讨论Clunis案的背景。本文使用StuartHall的工作作为分析工具来研究种族和代表性问题,以及社区护理失败后的道德恐慌。
    In December 2022, the death of Christopher Clunis was made public. He had actually died in February 2021. Christopher Clunis was convicted of the manslaughter of a stranger, Jonathan Zito. He attacked Mr Zito at a train station. This paper will argue that this terrible event became a totemic symbol of the wider failings of the policy of community care. The image of Clunis being driven away from Court was repeatedly used in newspaper and other media reports as a reference point. The image reflects a number of long-standing traits in the representation of the \"mentally ill.\" These are combined with a racial stereotype of Black men. The paper examines historical representations of the mentally ill as a context for a discussion of the Clunis case. The paper uses the work of Stuart Hall as an analytical tool to examine the questions of race and representation, and the moral panic following failings of community care.
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  • 文章类型: Journal Article
    目的:为了克服标准病例管理服务的有限效果,2017年推出了针对严重精神疾病患者的首尔强化病例管理计划(S-ICM).本研究旨在评估其减少住院时间的有效性。
    方法:从首尔精神卫生福利中心检索2019年4月至2020年3月的监测数据。总共包括759名患有严重精神疾病的参与者。比较了ICM前(上一年)和ICM期间每月的平均入院时间。对于ICM后观察亚组,比较了ICM前每月的平均入院时间,在ICM期间,和ICM后时期。为了确定ICM期间和ICM后入院的风险因素的相对贡献,进行多因素logistic回归分析。
    结果:ICM前期的平均住院时间明显长于ICM期间(1.47vs.0.26天)。在ICM录取期间的预测因素中,ICM前精神病患者入院是最重要的危险因素,其次是医疗援助受益人和自杀行为。在ICM后观察期的亚组分析中,前ICM,在ICM期间,ICM后平均住院时间为1.45、0.29和0.57天/月,分别。ICM前和ICM期间以及ICM前和ICM后期间的平均住院时间存在显着差异。ICM后入学风险包括ICM前入学,S-ICM持续时间<3个月,和慢性不稳定症状。
    结论:结果表明,S-ICM可有效减少精神病住院时间,至少在短期内。
    OBJECTIVE: To overcome the limited effectiveness of standard case management services, the Seoul Intensive Case Management program (S-ICM) for patients with serious mental illnesses was introduced in 2017. This study aimed to evaluate its effectiveness in reducing the length of hospital stay.
    METHODS: Monitoring data from April 2019 to March 2020 were retrieved from the Seoul Mental Health Welfare Center. A total of 759 participants with serious mental illnesses were included. The average length of admission per month was compared between the pre-ICM (previous year) and during-ICM periods. For post-ICM observation subgroup, average length of admission per month was compared between pre-ICM, during-ICM, and post-ICM periods. To determine the relative contributions of risk factors for during-ICM and post-ICM admission, multivariate logistic regression analyses were performed.
    RESULTS: The average admission stay for pre-ICM period was significantly longer than that for during-ICM period (1.47 vs. 0.26 days). Among the predictors for during-ICM admission, pre-ICM psychiatric admission was the most important risk factor, followed by medical aid beneficiary and suicidal behavior. In the subgroup analysis of the post-ICM observation period, the pre-ICM, during-ICM, and post-ICM average admission stays were 1.45, 0.29, and 0.57 days/month, respectively. There was a significant difference in the average length of stay between the pre-ICM and during-ICM periods and between the pre-ICM and post-ICM periods. Post-ICM admission risks included pre-ICM admission, S-ICM duration <3 months, and chronic unstable symptoms.
    CONCLUSIONS: The results suggest that the S-ICM effectively reduces psychiatric hospitalization duration, at least over a short-term period.
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  • 文章类型: Journal Article
    认证同行专家(CPS)是心理健康专业人员,他们从精神疾病和精神困扰的生活经验中汲取专业知识。他们讲述了一个非医学的故事,非临床方法为有心理健康困难的社区成员提供支持,强调导致精神困扰的社会环境因素的作用。他们的观点与主流精神病学的生物医学观点相反。虽然有大量关于CPS的文献,关于CPS如何参与和感知更广泛的心理健康系统的研究缺乏。他们通过移动过去的标签和病理学语言来抵制精神疾病的生物医学化,以促进精神疾病的康复并抵制污名化。从对同行专家的深入采访中得出,对同行组织的参与者观察,以及对全美同行专家的调查,Iaskthefollowingresearchquestions:HowandwhyareCPSchallengethemedicalmodelofminaldischarge?HowdoCPSconsidersocialenvironmentalfactorsinthecourseofdistressandwhatarethepotentialimplicationsforresistancetobiomedicationanddisginalization在他们对医学模式和精神卫生系统的批评中,积极抵制精神疾病的生物医学化,并关注导致痛苦经历的社会环境因素。这项研究对CPS的研究以及从精神疾病中康复的希望具有意义。
    Certified peer specialists (CPS) are mental health professionals who draw their expertise from lived experience with mental illness and mental distress. They tale a nonmedical, nonclinical approach to providing support to community members with mental health difficulties and in doing so, emphasize the role of social environmental factors that contribute to mental distress. Their perspectives are contrary to the biomedical perspective of mainstream psychiatry. While there is a significant body of literature on CPS, there is a dearth of research on how CPS engage in and perceive the broader mental health system. They resist the biomedicalization of mental illness by moving past labels and the language of pathology to facilitate recovery from mental illness and to resist stigma. Drawing from in-depth interviews with peer specialists, participant observation of a peer-run organization, and a survey of peer specialists across the United States, I ask the following research questions: How and why are CPS challenging the medical model of mental illness? How do CPS consider social environmental factors in the etiology of distress and what are the potential implications for resistance to both biomedicalization and stigmatization? My data suggest that CPS, in their critiques of the medical model and the mental health system, are actively resisting the biomedicalization of mental illness and focus on social environmental factors that contribute to experiences of distress. This research has meaningful implications for research on CPS and hope for recovery from mental illness.
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  • 文章类型: Case Reports
    背景:创伤聚焦认知行为疗法(TF-CBT)策略是治疗儿童创伤和创伤后应激障碍(PTSD)诊断的常见干预措施。随着COVID-19的出现,儿童发育的中断加上对技术和屏幕时间的强烈接触表明需要提供其他新方法来治疗小儿PTSD。虚拟现实(VR)已与基于证据的TF-CBT一起用作基于实验室的设置的干预,但从来没有像远程医疗一样。这些技术,包括用新型TheraVR软件编程的VR头戴式设备(HMD),对于心理疗法和创伤相关症状的治疗,可以重新定义儿科人群对治疗的反应.
    目的:这项探索性单病例研究的目的是使用VR作为远程健康来反映症状改善和患者参与。
    方法:患者是一名10岁的中东裔女孩,被诊断患有创伤和合并症。该患者处于离婚的父母共同监护之下,并提交了儿童保护服务报告,并转诊治疗。夜惊,幻觉,抑郁症,焦虑,隔离,并在治疗开始时评估包治病症状。临床分析符合早发性创伤后应激障碍的诊断标准,使用TF-CBT治疗7个月。使用交叉分析设计来比较从使用台式机和平板电脑同步技术的远程医疗提供护理到使用TheraVR软件的2DVR桌面远程医疗以及随后使用TheraVR软件的HMDVR远程医疗时,治疗效果和患者结果的改善。会议是在私人诊所进行的,为远程患者护理提供心理治疗,与家人的附带护理,并与患者的儿科医生协调临床护理。安全性和减少触发因素的方案由提供者进行临床监测。
    结果:在治疗过程中,从标准的远程医疗到2DVR,再到带有独立HMD的TheraVR,PTSD症状显著减轻.从使用具有面对面视频的标准视频会议到使用具有分配的场景环境的可定制的化身技术的转变呈现了患者保留和对治疗目标的跟进的增加。使用VR和TheraVR软件持续使用提供护理,证明了突破性的临床观察结果,患者设计了自己的干预措施来应对情绪,情绪调节,以及使用10种不同VR环境的负面认知过程。
    结论:这项研究表明,将VR作为一种更好的儿科护理方式,特别是针对年轻人群的潜在疗效。同时通过远程医疗改善与提供者的互动。这些发现表明,通过更大的临床试验进行进一步研究的价值,包括被诊断为严重创伤或创伤相关症状的儿科患者,以评估TheraVR软件的有效性。
    BACKGROUND: Trauma-focused cognitive behavioral therapy (TF-CBT) strategies are common interventions to treat child trauma and a posttraumatic stress disorder (PTSD) diagnosis in children with histories of sexual and physical abuse. With the advent of COVID-19, the disruption of child development combined with intense exposure to technology and screen time indicate a need for delivering other novel approaches to treat pediatric PTSD. Virtual reality (VR) has been used with evidence-based TF-CBT as an intervention in lab-based settings, but never as telehealth. Such technologies, including a VR head-mounted device (HMD) programmed with novel TheraVR software, for psychotherapy and treating trauma-related symptoms could redefine how pediatric populations respond to treatment.
    OBJECTIVE: The aim of this exploratory single-case study was to reflect symptom improvement and patient engagement using VR as telehealth.
    METHODS: The patient was a 10-year-old girl of Middle Eastern descent diagnosed with trauma and comorbid medical conditions. The patient was in divorced joint parental custody and a Child Protective Services report was made with referral for therapy. Night terrors, hallucinations, depression, anxiety, isolation, and encopresis symptoms were assessed at the beginning of treatment. Clinical analysis met the criteria for a diagnosis of early onset PTSD, which was treated over the course of 7 months using TF-CBT. A cross-analysis design was used to compare improved effectiveness in treatment and patient outcomes when moving from delivery of care with telehealth using desktop and tablet synchronous technology to 2D VR desktop telehealth with TheraVR software and subsequently HMD VR telehealth with TheraVR software. Sessions were conducted in private practice providing psychotherapy for remote patient care, collateral care with the family, and coordination of clinical care with the patient\'s pediatrician. Safety and protocols for reducing triggers were clinically monitored by the provider.
    RESULTS: Over the course of treatment, and moving from standard telehealth to 2D VR to TheraVR with a standalone HMD, there was a significant reduction in PTSD symptoms. The transfer from using the standard video conferencing with face-to-face video to using customizable avatar technology with an assigned scene environment presented an increase in patient retention and follow-through with the treatment goals. The continuous use of delivery of care using VR with the TheraVR software demonstrated breakthrough clinical observations where the patient devised her own interventions for coping with mood, emotional regulation, and negative cognitive processes using the 10 different VR environments.
    CONCLUSIONS: This study shows the potential efficacy in using VR specifically for younger populations as a better modality of pediatrics care, while improving engagement with the provider through telehealth. These findings suggest the value of further research through larger clinical trials including pediatric patients diagnosed with severe trauma or trauma-related symptoms to assess the effectiveness of TheraVR software.
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  • 文章类型: Journal Article
    背景:药物相关问题(MRP)对可预防的患者伤害和全球医疗保健支出有重要贡献。弱势群体,包括澳大利亚原住民(请注意,本文中使用的“土著”一词包括所有原住民和托雷斯海峡岛民,并承认他们丰富的传统和异质文化。)和患有严重和持续性精神疾病(SPMI)的人,可能会增加MRP的风险。药剂师主导的药物审查可以确定MRP的针对性行动。
    目的:描述社区药剂师在对澳大利亚土著居民和SPMI患者进行药物审查时发现的MRP和提出的建议。
    方法:通过两项澳大利亚试验招募参与者,测试新型社区药剂师主导的干预措施的可行性和/或有效性。土著药物审查服务(IMeRSe)可行性研究(2018年6月至2019年7月)和弥合社区药房中的身体和精神疾病之间的差距(PharMibridge)随机对照试验(2020年9月至2021年12月)。训练有素的社区药剂师根据参与者的文化和健康需求进行了药物审查。MRP,使用已建立的分类系统(DOCUMENT)记录和分类MRP严重程度和药剂师建议。MRP严重程度由药剂师和独立评估者评估。数据进行了描述性分析,和配对t检验用于比较严重程度评级。
    结果:药剂师在两项试验中确定了795例MRP,其中411例参与者(n=255IMeRSe,n=156PharMibridge)。在IMeRSe和PharMIbridge中,不坚持用药是最常见的(n=157,25.1%)和第二常见的(n=25,14.7%)MRP,分别。治疗不足是澳大利亚原住民样本中第二常见的MRP(n=139,22.2%),毒性/不良反应的报告在SPMI患者中最常见(n=41,24.1%).改变药物治疗是药剂师最常见的建议(在IMeRSe和PharMibridge中分别为40.2%和55.0%,分别)。严重等级各不相同,两组中大多数为“轻度”或“中度”。试验药剂师和独立评估者分配的严重程度等级存在显着差异。
    结论:社区药剂师确定了两个高危人群所经历的一系列MRP,最常见的非依从性和毒性或不良反应,在进行药物审查并提出不同的管理策略时,经常建议改变药物治疗。这些发现强调了更有针对性的方法来识别和管理初级保健中的MRP的机会,并且量身定制的社区药剂师主导的干预措施可能在这个领域具有价值。
    背景:澳大利亚和新西兰临床试验注册记录(IMeRSeACTRN12618000188235注册于2018年6月2日,PharMibridgeACTRN12620000577910注册于2020年5月18日)。
    BACKGROUND: Medication-related problems (MRPs) contribute significantly to preventable patient harm and global healthcare expenditure. Vulnerable populations, including Indigenous Australians (please note that the use of the term \'Indigenous\' in this paper includes all Aboriginal and Torres Strait Islander people and acknowledges their rich traditions and heterogenous cultures.) and people living with severe and persistent mental illness (SPMI), may be at increased risk of MRPs. Pharmacist-led medication reviews can identify MRPs for targeted action.
    OBJECTIVE: To characterize MRPs identified and recommendations made by community pharmacists during medication reviews conducted with Indigenous Australians and people living with SPMI.
    METHODS: Participants were recruited through two Australian trials testing the feasibility and/or effectiveness of novel community pharmacist-led interventions, the Indigenous Medication Review Service (IMeRSe) feasibility study (June 2018-July 2019) and Bridging the Gap between Physical and Mental Illness in Community Pharmacy (PharMIbridge) randomized controlled trial (September 2020-December 2021). Trained community pharmacists conducted medication reviews responsive to the cultural and health needs of participants. MRPs, MRP severity and pharmacist recommendations were documented and classified using an established classification system (DOCUMENT). MRP severity was assessed by pharmacists and an independent assessor. Data were analysed descriptively, and paired t-tests were used to compare severity ratings.
    RESULTS: Pharmacists identified 795 MRPs with 411 participants across both trials (n = 255 IMeRSe, n = 156 PharMIbridge). Non-adherence to medication was the most common (n = 157, 25.1%) and second-most common (n = 25, 14.7%) MRP in IMeRSe and PharMIbridge, respectively. Undertreatment was the second-most common MRP in the sample of Indigenous Australians (n = 139, 22.2%), and reports of toxicity/adverse reactions were most common in people living with SPMI (n = 41, 24.1%). A change in pharmacotherapy was the most frequent recommendation made by pharmacists (40.2% and 55.0% in IMeRSe and PharMIbridge, respectively). Severity ratings varied, with the majority being \'Mild\' or \'Moderate\' in both groups. Significant differences were found in the severity rating assigned by trial pharmacists and the independent assessor.
    CONCLUSIONS: Community pharmacists identified a range of MRPs experienced by two at-risk populations, most commonly non-adherence and toxicity or adverse reactions, when conducting medication reviews and proposed diverse strategies to manage these, frequently recommending a change in pharmacotherapy. These findings highlight the opportunity for more targeted approaches to identifying and managing MRPs in primary care and tailored community pharmacist-led interventions may be of value in this space.
    BACKGROUND: Australian and New Zealand Clinical Trial Registry records (IMeRSe ACTRN12618000188235 registered 06/02/2018 & PharMIbridge ACTRN12620000577910 registered 18/05/2020).
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  • 文章类型: Case Reports
    与介入程序有关的情绪混乱可能会加剧以前的精神疾病,甚至引发新的精神病理学。尽管众所周知,精神健康障碍对心脏预后的有害影响,心理障碍的研究相对不足,但对起搏后患者的整体健康至关重要.在本病例系列中,我们介绍了在坦桑尼亚国家转诊心脏中心接受永久性起搏器植入的一组患者中观察到的一系列精神疾病。5名年龄在58至81岁之间的非洲裔人被送往JakayaKikwete心脏研究所,其临床条件需要永久性起搏器植入。所有五个人都否认有精神病史,然而,经过彻底的精神病学审查;器质性脑综合征,恐慌症,短暂的精神病,达到了适应障碍和重度抑郁障碍的诊断。所有五个人都成功地接受了医学心理治疗。最后,这个案例系列说明了对植入式心脏设备的不良心理适应的各种后果,它强调了对此类患者进行持续心理评估的重要性。
    Emotional disarray linked to interventional procedures may potentially aggravate previous psychiatric conditions or even precipitate new psychopathologies. Despite of the well-known deleterious impact of mental health disorders on cardiac outcomes, psychological disturbances are relatively understudied yet of vital importance to the overall health of post-pacing patients. In this case series we present a spectrum of mental illnesses observed in a cohort of patients who underwent permanent pacemaker implantation in Tanzania\'s national referral cardiac centre. Five individuals of African origin aged between 58 and 81 years presented to Jakaya Kikwete Cardiac Institute with clinical conditions warranting permanent pacemaker implantation. All five denied prior history of mental illness, however, after thorough psychiatric reviews; organic brain syndrome, panic disorder, brief psychotic disorder, adjustment disorder and major depressive disorder diagnoses were reached. All five were successfully channeled for medical psychotherapy. To conclude, this case series illustrates variable consequences of poor psychological adaptation to implantable cardiac devices, and it underscores the importance of continued psychological evaluation to such patients.
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  • 文章类型: Journal Article
    恢复资本(RC)包括个人可以用来从物质使用障碍(SUD)中恢复的广泛资源。它由五个子域组成:人类,社会,文化,金融,社区RC。负恢复资本(NRC)代表了恢复的障碍。在复杂的多品种种群中对(N)RC的研究很少。这项研究提供了对(N)RC在三个SUD个体中的可行性的初步探索,精神病合并症,和住院成瘾治疗中的智力障碍(三重诊断)。我们收集了案件档案数据,排名恢复目标,并进行了后续访谈。对数据进行模板分析,使用(N)个RC域作为代码。所有领域都是普遍和相关的,表现出动态和互惠的效果,受作为催化剂的关键生活事件的影响。值得注意的是,治疗期间,尽管在其他领域存在挑战,但患者优先考虑个人技能发展.RC成为一个有价值的概念,用于绘制具有三重诊断的个体的恢复障碍和促进者,作为医学模式的替代方案,并补充生物心理社会模式。它提供了一个系统的框架,以评估复杂病例中恢复的关键因素,并相应地调整干预措施。未来的研究应探索NRC域的交叉点和(N)RC的动态性质,以增强对三重诊断个体面临的挑战的理解。
    Recovery capital (RC) encompasses the wide range of resources individuals can employ to recover from Substance Use Disorder (SUD). It consists of five subdomains: human, social, cultural, financial, and community RC. Negative recovery capital (NRC) represents the obstacles to recovery. Research on (N)RC in complex multimorbid populations is scarce. This study offers an initial exploration of the viability of (N)RC in three individuals with SUD, psychiatric comorbidities, and an intellectual disability (a triple diagnosis) in inpatient addiction treatment. We collected case file data, ranked recovery goals, and conducted follow-up interviews. The data were subjected to template analysis, using (N)RC domains as codes. All domains were prevalent and relevant, showing dynamic and reciprocal effects, influenced by critical life events acting as catalysts. Notably, during treatment, patients prioritized individual skill development despite challenges in other domains. RC emerges as a valuable concept for mapping recovery barriers and facilitators in individuals with a triple diagnosis, serving as an alternative to the medical model and complementing the biopsychosocial model. It provides a systematic framework to assess critical factors for recovery in complex cases and accordingly align interventions. Future studies should explore the intersections of NRC domains and the dynamic nature of (N)RC to enhance the understanding of the challenges faced by individuals with a triple diagnosis.
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