■尽管日本的肺移植(LTs)数量很少,10个LT设施获得认证,并报告了良好的结果。进行了数据库审查,以澄清日本LT设施的病例量对短期和长期结果的影响。
■使用日本肺和心肺移植学会(JSLHT)的数据库分析了2000年至2021年在日本治疗的所有尸体LT病例。代表的9个机构被归类为低容量(LV;<80例累积LT病例,<8LTs/年,n=5)和高容量(HV;≥80例累积LT病例,≥8LTs/年,n=4)中心。90天和1年死亡率,以及5年和10年生存数据进行了评估.
■在9个机构中共进行了658具尸体LTs。HV和LV中心的90天死亡率分别为3.5%和3.9%,分别(P=0.801),而1年死亡率为9.2%和11.5%,分别为(P=0.199)。此外,显示病例体积的Kaplan-Meier曲线的log-rank分析未显示HV和LV中心之间长期生存的显着差异(P=0.272),尽管LV中心的长期结局差异很大(P=0.030)。
■病例量对日本LT后的短期或长期结果没有影响,而与HV中心相比,LV中心的长期结局差异较大.
UNASSIGNED: Despite the low number of lung transplantations (LTs) in Japan, 10 LT facilities are accredited and good outcomes have been reported. A database review was conducted to clarify the impact of
case volume at LT facilities in Japan on short- and long-term outcomes.
UNASSIGNED: All cadaveric LT cases treated between 2000 and 2021 in Japan were analyzed using the database of the Japanese Society of Lung and Heart-Lung Transplantation (JSLHT). The nine institutions represented were categorized into the low-volume (LV; <80 cumulative LT cases, <8 LTs/year, n=5) and high-volume (HV; ≥80 cumulative LT cases, ≥8 LTs/year, n=4) centers. Ninety-day and 1-year mortality, as well as 5- and 10-year survival data were evaluated.
UNASSIGNED: A total of 658 cadaveric LTs were performed at the nine institutions. The 90-day rates of mortality at the HV and LV centers were 3.5% and 3.9%, respectively (P=0.801), while the 1-year mortality rates were 9.2% and 11.5%, respectively (P=0.199). Additionally, log-rank analysis of Kaplan-Meier curves showing
case volume did not reveal a significant difference in long-term survival between the HV and LV centers (P=0.272), though the LV centers had wide differences for long-term outcomes (P=0.030).
UNASSIGNED: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers.