PDF(Pubmed)
Abstract：
Retroperitoneal sarcoma (RPS) is a rare disease. RPS invading the abdominal aorta is exceedingly rare and has a poor prognosis. There have been scattered cases of RPS treated with combined abdominal aortic replacement. However, the average survival time for these cases was only 8 months, with a 2-year survival rate of 21%, indicating a poor prognosis. In this case study, a 44-year-old man presented to our hospital complaining of abdominal pain. Multiple imaging findings suggested a retroperitoneal mass that was diagnosed as a malignant tumor. The patient underwent tumor resection with abdominal aortic replacement due to an RPS tumor invading the abdominal aorta. The histopathological grade was determined to be grade 3, the most malignant grade tumor, according to the Fédération Nationale des Centres de Lutte Contre le Cancer grading system. Postoperative chemotherapy with doxorubicin and ifosfamide was administered for five cycles. The patient has been alive for over 8 years after the operation without any recurrence. This case presents a long-term survival of RPS requiring abdominal aortic replacement.
摘要：
腹膜后肉瘤（RPS）是一种罕见的疾病。RPS侵入腹主动脉极为罕见，预后不良。有分散的RPS病例采用联合腹主动脉置换术治疗。然而,这些病例的平均生存时间仅为8个月，2年生存率为21%,表明预后不良。在这个案例研究中,一名44岁的男子出现在我们医院，抱怨腹痛。多项影像学发现提示腹膜后肿块被诊断为恶性肿瘤。由于RPS肿瘤侵入腹主动脉，该患者接受了腹主动脉置换的肿瘤切除术。组织病理学分级确定为3级，恶性程度最高的肿瘤，根据国家癌症中心的分级系统。术后给予阿霉素和异环磷酰胺化疗五个周期。手术后患者存活超过8年，无复发。该病例显示需要腹主动脉置换的RPS长期存活。
