light

Light
  • 文章类型: Journal Article
    在现代畜牧业中,压力可以被视为由暴露于不利环境条件触发的自动响应。这种反应可以从轻度不适到严重后果,包括死亡率。家禽业,这对人类营养有很大的贡献,不能免除这个问题。尽管基因选择已经使用了几十年来提高产量,这也导致了不良的压力弹性。压力是通过一系列的生理反应表现出来的,比如压力刺激的识别,激活交感神经系统和肾上腺髓质,和随后的荷尔蒙级联。虽然可以忍受短暂的压力,长时间接触会产生更严重的后果。例如,环境温度的极端波动会导致活性氧的积累,生殖性能受损,免疫力降低。此外,家禽屠宰场噪音过多与鸟类行为改变和生产效率下降有关。机械振动也已被证明对运输过程中肉鸡的肉质量以及孵化场中的蛋质量和孵化率产生负面影响。最后,产蛋受到光照强度和方案的严重影响,光管理不足会导致缺陷,包括视觉异常,骨骼畸形,和循环问题。尽管越来越多的证据表明环境压力因素对家禽生理的影响,研究中压力源的表现不成比例。最近的研究集中在慢性热应激,反映了科学界目前对气候变化的兴趣。因此,这篇综述旨在强调家禽生产中的主要非生物应激源,并阐明其潜在机制,解决需要更全面地了解不同环境背景下的压力。
    In modern animal husbandry, stress can be viewed as an automatic response triggered by exposure to adverse environmental conditions. This response can range from mild discomfort to severe consequences, including mortality. The poultry industry, which significantly contributes to human nutrition, is not exempt from this issue. Although genetic selection has been employed for several decades to enhance production output, it has also resulted in poor stress resilience. Stress is manifested through a series of physiological reactions, such as the identification of the stressful stimulus, activation of the sympathetic nervous system and the adrenal medulla, and subsequent hormonal cascades. While brief periods of stress can be tolerated, prolonged exposure can have more severe consequences. For instance, extreme fluctuations in environmental temperature can lead to the accumulation of reactive oxygen species, impairment of reproductive performance, and reduced immunity. In addition, excessive noise in poultry slaughterhouses has been linked to altered bird behaviour and decreased production efficiency. Mechanical vibrations have also been shown to negatively impact the meat quality of broilers during transport as well as the egg quality and hatchability in hatcheries. Lastly, egg production is heavily influenced by light intensity and regimens, and inadequate light management can result in deficiencies, including visual anomalies, skeletal deformities, and circulatory problems. Although there is a growing body of evidence demonstrating the impact of environmental stressors on poultry physiology, there is a disproportionate representation of stressors in research. Recent studies have been focused on chronic heat stress, reflecting the current interest of the scientific community in climate change. Therefore, this review aims to highlight the major abiotic stressors in poultry production and elucidate their underlying mechanisms, addressing the need for a more comprehensive understanding of stress in diverse environmental contexts.
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  • 文章类型: Journal Article
    背景:照顾阿尔茨海默病和相关痴呆症患者的一个共同挑战是管理痴呆症(BPSD)的行为和心理症状。有效管理BPSD将提高痴呆症患者的生活质量,减轻护理人员的负担,降低医疗成本。
    目的:在这篇综述中,我们寻求(1)研究与光有关的室内环境质量参数,噪音,温度,和湿度与BPSD相关,以及如何控制这些参数可以帮助管理这些症状和(2)确定该领域的当前知识状态,目前的研究空白,和潜在的未来方向。
    方法:在CINAHL中进行了搜索,Embase,MEDLINE,和PsycINFO数据库,用于2007年1月至2024年2月发表的论文。我们搜索了研究与光有关的室内环境质量参数之间的关系的研究,噪音,温度,湿度和BPSD。
    结果:在2020年10月的原始搜索中总共确定了3123篇论文。经过另外2次搜索和筛选,纳入了5476篇论文中的38篇(0.69%)。在包括的论文中,光是研究最多的环境因素(34/38,89%),而研究其他环境因素与BPSD之间关系的研究较少(从5/38,13%到11/38,29%)。在38项研究中,8(21%)检测了多个室内环境质量参数。在38项研究中,有6项(16%)是环境评估的唯一来源。关于躁动和光疗之间关系的发现是矛盾的,而研究BPSD与温度或湿度之间关系的研究都是观察性的。结果表明,当环境因素被认为对痴呆症患者刺激过度或刺激不足时,行为症状往往会加剧。
    结论:这项范围审查的结果可能会为长期护理单位和老年人住房的设计提供信息,以支持就地老龄化。还需要更多的研究来更好地了解室内环境质量参数与BPSD之间的关系,并且需要对室内环境质量参数和行为症状进行更客观的测量。未来的一个方向是在实时评估中纳入客观感知和先进的计算方法,以启动及时的环境干预措施。更好地管理BPSD将使患者受益,看护者,和医疗保健系统。
    BACKGROUND: A common challenge for individuals caring for people with Alzheimer disease and related dementias is managing the behavioral and psychological symptoms of dementia (BPSD). Effective management of BPSD will increase the quality of life of people living with dementia, lessen caregivers\' burden, and lower health care cost.
    OBJECTIVE: In this review, we seek to (1) examine how indoor environmental quality parameters pertaining to light, noise, temperature, and humidity are associated with BPSD and how controlling these parameters can help manage these symptoms and (2) identify the current state of knowledge in this area, current gaps in the research, and potential future directions.
    METHODS: Searches were conducted in the CINAHL, Embase, MEDLINE, and PsycINFO databases for papers published from January 2007 to February 2024. We searched for studies examining the relationship between indoor environmental quality parameters pertaining to light, noise, temperature, and humidity and BPSD.
    RESULTS: A total of 3123 papers were identified in the original search in October 2020. After an additional 2 searches and screening, 38 (0.69%) of the 5476 papers were included. Among the included papers, light was the most studied environmental factor (34/38, 89%), while there were fewer studies (from 5/38, 13% to 11/38, 29%) examining the relationships between other environmental factors and BPSD. Of the 38 studies, 8 (21%) examined multiple indoor environmental quality parameters. Subjective data were the only source of environmental assessments in 6 (16%) of the 38 studies. The findings regarding the relationship between agitation and light therapy are conflicted, while the studies that examined the relationship between BPSD and temperature or humidity are all observational. The results suggest that when the environmental factors are deemed overstimulating or understimulating for an individual with dementia, the behavioral symptoms tend to be exacerbated.
    CONCLUSIONS: The findings of this scoping review may inform the design of long-term care units and older adult housing to support aging in place. More research is still needed to better understand the relationship between indoor environmental quality parameters and BPSD, and there is a need for more objective measurements of both the indoor environmental quality parameters and behavioral symptoms. One future direction is to incorporate objective sensing and advanced computational methods in real-time assessments to initiate just-in-time environmental interventions. Better management of BPSD will benefit patients, caregivers, and the health care system.
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  • 文章类型: Journal Article
    定量相位成像(QPI)是非侵入性的,提供有关所研究样品的内在信息的无标签技术。这些信息包括结构,函数,和样品的动力学。QPI克服了常规荧光显微镜在对样品的光毒性和荧光团的光漂白方面的局限性。因此,QPI在估计三维(3D)结构和动力学中的应用非常适合从细胞内细胞器到高度散射的多细胞样品的一系列样品,同时允许更长的观察窗口。
    我们的目标是提供3DQPI和相关的基于相位的测量技术的全面回顾,以及对样品动力学估计方法的讨论。
    我们介绍了从106种出版物中收集的信息,这些出版物涵盖了3D光散射的理论描述以及用于研究样品的结构和动力学的相关测量技术的实施。最后,我们讨论了所审查的技术在生物医学领域的应用。
    QPI已成功应用于3D样品成像。基于散射的对比度提供指示疾病状态的样本的固有量的测量。成长阶段,或整体动态。
    我们回顾了用于生物样品的3D成像和动力学估计的最先进的QPI技术。讨论了各种技术的理论和实验方面。我们还介绍了所讨论的技术在生物医学和生物学研究中的应用。
    UNASSIGNED: Quantitative phase imaging (QPI) is a non-invasive, label-free technique that provides intrinsic information about the sample under study. Such information includes the structure, function, and dynamics of the sample. QPI overcomes the limitations of conventional fluorescence microscopy in terms of phototoxicity to the sample and photobleaching of the fluorophore. As such, the application of QPI in estimating the three-dimensional (3D) structure and dynamics is well-suited for a range of samples from intracellular organelles to highly scattering multicellular samples while allowing for longer observation windows.
    UNASSIGNED: We aim to provide a comprehensive review of 3D QPI and related phase-based measurement techniques along with a discussion of methods for the estimation of sample dynamics.
    UNASSIGNED: We present information collected from 106 publications that cover the theoretical description of 3D light scattering and the implementation of related measurement techniques for the study of the structure and dynamics of the sample. We conclude with a discussion of the applications of the reviewed techniques in the biomedical field.
    UNASSIGNED: QPI has been successfully applied to 3D sample imaging. The scattering-based contrast provides measurements of intrinsic quantities of the sample that are indicative of disease state, stage of growth, or overall dynamics.
    UNASSIGNED: We reviewed state-of-the-art QPI techniques for 3D imaging and dynamics estimation of biological samples. Both theoretical and experimental aspects of various techniques were discussed. We also presented the applications of the discussed techniques as applied to biomedicine and biology research.
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  • 文章类型: Journal Article
    定量相位成像(QPI)技术在无标签的情况下提供有关感兴趣样品的内在信息,非侵入性的方式,并且在广泛的生物医学应用中具有巨大的潜力,对体外样品的自然状态的扰动可以忽略不计。
    我们旨在对应用于细胞和组织等生物样品的光-物质相互作用的散射公式进行深入的回顾,讨论相关的定量相位测量技术,并提供各种已报告应用程序的摘要。
    我们从生物样品的散射理论和散射特性开始,然后探索用于测量结构和动力学的2DQPI的各种显微镜配置。
    我们回顾了157种出版物,介绍了一系列QPI技术,并讨论了每种技术的合适应用。我们还介绍了与讨论的技术相关的相位重建的理论框架,并强调了它们的有效性领域。
    我们为各种QPI技术提供了详细的理论和系统级信息。我们的研究可以作为新研究人员寻找QPI方法和相关应用的详尽文献综述的指南。
    UNASSIGNED: Quantitative phase imaging (QPI) techniques offer intrinsic information about the sample of interest in a label-free, noninvasive manner and have an enormous potential for wide biomedical applications with negligible perturbations to the natural state of the sample in vitro.
    UNASSIGNED: We aim to present an in-depth review of the scattering formulation of light-matter interactions as applied to biological samples such as cells and tissues, discuss the relevant quantitative phase measurement techniques, and present a summary of various reported applications.
    UNASSIGNED: We start with scattering theory and scattering properties of biological samples followed by an exploration of various microscopy configurations for 2D QPI for measurement of structure and dynamics.
    UNASSIGNED: We reviewed 157 publications and presented a range of QPI techniques and discussed suitable applications for each. We also presented the theoretical frameworks for phase reconstruction associated with the discussed techniques and highlighted their domains of validity.
    UNASSIGNED: We provide detailed theoretical as well as system-level information for a wide range of QPI techniques. Our study can serve as a guideline for new researchers looking for an exhaustive literature review of QPI methods and relevant applications.
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  • 文章类型: Journal Article
    光调节人类的图像和各种非图像形成反应,包括对注意力和情感的急性影响。为了促进对光的直接影响的理解,本系统综述描述了单色/窄带宽和多色白光在白天对注意力的不同方面的急性影响(警觉性,持续关注,工作记忆,注意控制和灵活性),和影响措施(自我报告措施,基于性能的测试,心理生理措施)在健康的,成人受试者。Original,根据预定义的纳入和排除标准,纳入了2000年至2024年5月发表的同行评审(准)实验研究.评估研究质量,和结果在注意力和影响方面进行综合,并根据光干预进行分组;单色/窄带宽或多色白光(常规白光,明亮的白色,和白色具有高相关色温(CCT))。纳入研究(n=62)的结果表明,警觉性和工作记忆受光的影响最大。在暴露于窄带宽长波长光的情况下,警觉性的脑电图标记改善最大,普通的白色,和白光与高CCT。在明亮的白光下,自我报告的警觉性和工作记忆的测量得到了最大的改善。测试对持续注意力,注意力控制和灵活性的急性影响的研究结果尚无定论。基于性能和心理生理的影响措施仅受窄带宽长波长光的影响。多色白光对自我报告的影响产生混合影响。在光刺激特征和光刺激报告以及影响光急性效应的变量控制方面,研究具有很强的异质性。
    Light regulates both image- and various non-image forming responses in humans, including acute effects on attention and affect. To advance the understanding of light\'s immediate effects, this systematic review describes the acute effects of monochromatic/narrow bandwidth and polychromatic white light during daytime on distinct aspects of attention (alertness, sustained attention, working memory, attentional control and flexibility), and measures of affect (self-report measures, performance-based tests, psychophysiological measures) in healthy, adult human subjects. Original, peer-reviewed (quasi-) experimental studies published between 2000 and May 2024 were included according to predefined inclusion and exclusion criteria. Study quality was assessed, and results were synthesized across aspects of attention and affect and grouped according to light interventions; monochromatic/narrowband-width or polychromatic white light (regular white, bright white, and white with high correlated color temperature (CCT)). Results from included studies (n = 62) showed that alertness and working memory were most affected by light. Electroencephalographic markers of alertness improved the most with exposure to narrow bandwidth long-wavelength light, regular white, and white light with high CCT. Self-reported alertness and measures of working memory improved the most with bright white light. Results from studies testing the acute effects on sustained attention and attentional control and flexibility were inconclusive. Performance-based and psychophysiological measures of affect were only influenced by narrow bandwidth long-wavelength light. Polychromatic white light exerted mixed effects on self-reported affect. Studies were strongly heterogeneous in terms of light stimuli characteristics and reporting of light stimuli and control of variables influencing light\'s acute effects.
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  • 文章类型: Journal Article
    二氧化钛(TiO2)基光催化剂已被广泛用作降解水和空气中各种持久性有机化合物(POC)的光催化剂。降解机理涉及高活性氧的产生,如羟基自由基,它们与有机化合物反应,分解它们的化学键,最终将它们矿化成无害的产物。在药物和农药分子的情况下,TiO2和改性TiO2光催化能有效降解多种化合物,包括抗生素,杀虫剂,和除草剂。主要的缺点是生产危险的中间产品,这在目前可用的文献中并不经常提到。TiO2光催化对这些化合物的降解速率取决于化合物的化学结构等因素,TiO2催化剂的浓度,强度,光源,以及溶液中其他有机或无机物质的存在。探索降解机制的理解,以获得对中间体的见解。此外,解决了响应面方法(RSM)的利用,为增强反应堆的可扩展性提供了潜在的途径。总的来说,TiO2光催化是一种很有前途的制药和农药废水处理技术,但是需要进一步的研究来优化工艺条件并了解降解产物的命运和毒性。 .
    Titanium dioxide (TiO2) based photocatalysts have been widely used as a photocatalyst for the degradation of various persistent organic compounds in water and air. The degradation mechanism involves the generation of highly reactive oxygen species, such as hydroxyl radicals, which react with organic compounds to break down their chemical bonds and ultimately mineralize them into harmless products. In the case of pharmaceutical and pesticide molecules, TiO2and modified TiO2photocatalysis effectively degrade a wide range of compounds, including antibiotics, pesticides, and herbicides. The main downside is the production of dangerous intermediate products, which are not frequently addressed in the literature that is currently available. The degradation rate of these compounds by TiO2photocatalysis depends on factors such as the chemical structure of the compounds, the concentration of the TiO2catalyst, the intensity, the light source, and the presence of other organic or inorganic species in the solution. The comprehension of the degradation mechanism is explored to gain insights into the intermediates. Additionally, the utilization of response surface methodology is addressed, offering a potential avenue for enhancing the scalability of the reactors. Overall, TiO2photocatalysis is a promising technology for the treatment of pharmaceutical and agrochemical wastewater, but further research is needed to optimize the process conditions and to understand the fate and toxicity of the degradation products.
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  • 文章类型: Journal Article
    伤口是一个日益增长的全球性问题,需要更多的关注。为了加快伤口愈合,技术正在开发中,和不同波长的发光二极管(LED)设备正在探索它们对愈合过程的刺激影响。本文提出了一个系统的文献综述,旨在汇编,组织,分析LED器件对伤口愈合的影响。此评论已在PROSPERO平台[CRD42023403870]上注册。两名失明的作者在Pubmed中进行了搜索,WebofScience,Scopus,Embase,和ScienceDirect数据库。包括评估伤口愈合过程中LED利用率的体外和体内实验研究。搜索产生了1010项研究,其中27人被列入审查范围。发现LED刺激不同的愈合途径,促进细胞增殖和迁移,血管生成刺激,胶原蛋白沉积增加,和炎症反应的调节。因此,可以得出结论,LED刺激细胞和分子过程取决于所使用的参数。效果取决于所使用的标准。绿色和红色LED对细胞迁移和增殖的影响较好。细胞外基质成分和血管生成受所有波长的调节,炎症的调节由绿色,红色,和红外LED。
    Wounds represent a growing global issue demanding increased attention. To expedite wound healing, technologies are under development, and light emitting diode (LED) devices of varying wavelengths are being explored for their stimulating influence on the healing process. This article presents a systematic literature review aiming to compile, organize, and analyze the impacts of LED devices on wound healing. This review is registered on the PROSPERO platform [CRD42023403870]. Two blinded authors conducted searches in the Pubmed, Web of Science, Scopus, Embase, and ScienceDirect databases. In vitro and in vivo experimental studies assessing LED utilization in the wound healing process were included. The search yielded 1010 studies, of which 27 were included in the review. It was identified that LED stimulates different healing pathways, promoting enhanced cell proliferation and migration, angiogenesis stimulation, increased collagen deposition, and modulation of the inflammatory response. Thus, it can be concluded that the LED stimulates cellular and molecular processes contingent on the utilized parameters. The effects depend on the standards used. Cell migration and proliferation were better influenced by green and red LED. The extracellular matrix components and angiogenesis were regulated by all wavelengths and the modulation of inflammation was mediated by green, red, and infrared LEDs.
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  • 文章类型: Journal Article
    光催化被认为是利用可见光解决能源和环境问题的最有前途的方法之一。石墨碳氮化物(g-C3N4),具有适度的带隙(〜2.7eV)一直是环境光催化的闪点,因为它可以在可见光下更好地工作,可以使用低成本材料通过简单的合成工艺合成,热和化学稳定。由于某些限制,例如可见光吸收能力不足,g-C3N4的光催化性能仍不令人满意,低电子空穴分离效率,高重组率,较差的表面积。掺杂的介绍,带结构工程,异质结的缺陷和设计,复合材料等.进行了调查,以扩大其应用范围。在所有这些修改中,元素掺杂是通过改变光学和电子性质来增强光催化活性的合适且成功的替代方法。本文综述了元素掺杂及其在水介质中光催化有机污染物修复中的应用进展和趋势。已经讨论了非均相光催化,特别是基于g-C3N4的光催化的基本光催化活性。非金属掺杂的好处,通过掺杂元素增强光催化性能,兴奋剂所包含的机制,共掺杂的优点已经被解释。Mono,Bi,综述了三非金属掺杂g-C3N4及其在可见光光催化去除水介质中有机污染物中的应用。光催化系统的生命周期评价(LCA)已成为重点。考虑到经济方面,未来的研究应集中在光催化过程的大规模应用上。建议进行严格的生命周期评估,以部署基于非金属掺杂的g-C3N4的光催化技术,以成功实现商业应用。
    Photocatalysis is recognized to be one of the most promising ways to address energy and environmental issues by utilizing visible light. Graphitic carbon nitride (g-C3N4), with a moderate band gap (∼2.7 eV) has been the flashpoint in environmental photocatalysis as it can work better under visible light, can be synthesized by a facile synthesis process using low-cost materials, thermally and chemically stable. Still the photocatalytic performance of g-C3N4 is not satisfactory because of certain limitations such as insufficient visible light absorption capacity, low electron-hole separation efficiency, high recombination rate, poor surface area. Introduction of doping, band structure engineering, defecting and designing of heterojunction, composites etc. were investigated to amplify its applications. Among all these modifications, elemental doping is a suitable and successful alternative for the enhancement of the photocatalytic activity by changing the optical and electronic properties. This review emphasizes on advancement and trends of elemental doping and its application on photocatalytic organic pollutant remediation in aqueous medium. The fundamental photocatalytic activity of heterogeneous photocatalysis and specifically g-C3N4-based photocatalysis have been discussed. The benfits of non-metal doping, enhanced photocatalytic performance by doping element, mechanism invloved in doping, advantages of co-doping has been explained. Mono, bi, and tri non-metal doped g-C3N4 and their application for the removal of organic pollutants from water medium by visible light photocatalysis has been summerized. Life cycle assessment (LCA) of photocatalytic system has been highlighted. Future research should focus on the large-scale application of the photocatalysis process considering the economic aspects. A rigorous life cycle assessment for deploying the non-metal doped g-C3N4-based photocatalysis technology for successful commercial application is recommended.
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  • 文章类型: Systematic Review
    分析钝器创伤的能力对于破译有关伤害机制的有价值线索以及作为医学法律调查的证据至关重要。在过去的十年中,已经研究了替代光源(ALS)的使用,并建议在瘀伤评估期间优于常规白光(CWL)。为了响应全世界对该技术日益增长的兴趣,根据系统评价和荟萃分析(PRISMA)的首选报告项目对文献进行了系统综述,以探讨ALS检测和观察瘀伤的能力.从最初的4055条记录中确定,10项研究符合合格标准,并入选本综述.评估还包括一个新颖的框架,被称为SPICOT,进一步系统地评估法医文献中的科学证据和偏见风险。分析表明,红外或紫外光谱范围内的窄带波长在可视化或检测瘀伤方面并没有明显优于CWL。然而,可见光谱内的波长,特别是415nm与长通或带通黄色滤光片相结合,更有效。然而,大多数选定的研究只涉及ALS的敏感性,因此,只有在已知瘀伤的位置时,结果才可能被认为是有效的。需要进一步调查以了解ALS的特殊性,特别是如何使用外用化妆品,以前的伤口/疤痕组织,纹身,痣和雀斑可能会影响检测。在将ALS实施为常规实践之前,在前景讨论中也应考虑对增强的可视化创伤的解释的伦理关注。然而,这篇综述发现,可见光谱内的窄带ALS证明了改善损伤记录的潜力,在瘀伤的检测和可视化方面优于CWL。
    The ability to analyze blunt-force trauma is crucial for deciphering valuable clues concerning mechanisms of injury and as evidence for medico-legal investigations. The use of alternate light sources (ALS) has been studied over the past decade, and is proposed to outperform conventional white light (CWL) during bruise assessments. In response to the growing interest of the technology worldwide, a systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) to address the ability of ALS to detect and visualize bruising. From an initial 4055 records identified, ten studies met the eligibly criteria and were selected for this review. Evaluation also included a novel framework, referred to as SPICOT, to further systematically assess both scientific evidence and risk of bias in forensic literature. Analysis reveals that narrowband wavelengths within in the infrared or ultraviolet spectral ranges do not significantly outperform CWL in visualizing or detecting bruising. However, wavelengths within the visible spectrum, particularly 415 nm combined with longpass or bandpass yellow filters, are more effective. However, the majority of selected studies only address the sensitivity of ALS, and therefore, results may only be considered valid when the location of a bruise is known. Further investigation is required to understand the specificity of ALS, in particular how the use of topical cosmetic products, previous wounds/scar-tissue, tattoos, moles and freckles may affect detection. The ethical concern regarding the interpretation of enhanced visualized trauma should also be considered in prospect discussions prior to implementing ALS into routine practice. Nevertheless, this review finds that narrowband ALS within the visible spectrum demonstrates potential for improved injury documentation, outperforming CWL in the detection and visualization of bruising.
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  • 文章类型: Journal Article
    光生物调节(PBM)是利用光来调节细胞功能和生物过程的程序。在过去的几十年里,由于其非侵入性和最小的副作用,PBM因其在各种医疗应用中的潜力而获得了相当大的关注。我们进行了叙事回顾,包括关于光生物调节的文章,LED光疗法或低水平激光治疗及其在过去6年中发表的皮肤病学应用,包括研究研究,临床试验,和技术发展。这篇综述强调了PBM背后的行动机制,包括与细胞发色团的相互作用和细胞内信号通路的激活。总结了来自临床试验和实验研究的证据,以评估PBM在临床实践中的疗效,并特别强调皮肤病学。此外,PBM技术的进步,例如新颖的光源和治疗方案,在优化治疗结果和改善患者护理的背景下进行了讨论。这篇叙述性综述强调了PBM作为一种具有广泛临床适用性的非侵入性治疗方法的有希望的作用。尽管需要进一步研究以制定标准协议,PBM在现代医疗保健实践中具有解决各种医疗状况和增强患者预后的巨大潜力。
    Photobiomodulation (PBM) is a procedure that uses light to modulate cellular functions and biological processes. Over the past decades, PBM has gained considerable attention for its potential in various medical applications due to its non-invasive nature and minimal side effects. We conducted a narrative review including articles about photobiomodulation, LED light therapy or low-level laser therapy and their applications on dermatology published over the last 6 years, encompassing research studies, clinical trials, and technological developments. This review highlights the mechanisms of action underlying PBM, including the interaction with cellular chromophores and the activation of intracellular signaling pathways. The evidence from clinical trials and experimental studies to evaluate the efficacy of PBM in clinical practice is summarized with a special emphasis on dermatology. Furthermore, advancements in PBM technology, such as novel light sources and treatment protocols, are discussed in the context of optimizing therapeutic outcomes and improving patient care. This narrative review underscores the promising role of PBM as a non-invasive therapeutic approach with broad clinical applicability. Despite the need for further research to develop standard protocols, PBM holds great potential for addressing a wide range of medical conditions and enhancing patient outcomes in modern healthcare practice.
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