jejunum

空肠
  • 文章类型: Journal Article
    背景:喂养问题在有复杂医疗问题或急危重症的儿童中很常见,可能需要肠内营养。在某些情况下,胃管喂养耐受性差或可能不可行.尽管对口服和胃肠内治疗方案进行了适当调整,但当饲料不耐受持续存在时,空肠管喂养可以被认为是营养支持的一种选择。
    方法:召开了澳大利亚肠外和肠内营养学会多学科专家工作组会议。他们确定了儿童空肠管喂养的主题问题和五个关键领域。在Pubmed上进行了文献检索,Embase,和所有相关研究的Medline,2000年1月至2022年9月(n=103)。研究使用国家卫生和医学研究委员会指南进行评估,以生成声明,作为一个小组讨论,然后使用修改后的Delphi程序对声明进行投票,以确定共识。
    结果:针对五个关键领域共创建了24个共识声明:患者选择,进料管的类型和选择,并发症,临床使用空肠管,后续行动,和重新评估。
    结论:在有复杂医疗需求的儿科患者中,空肠管喂养是一种安全有效的营养方式,不能用胃管喂养的人。适当的患者选择很重要,因为与空肠管喂养相关的并发症并不少见,虽然大多是未成年人,可能是重要的或需要重新插入管。所有接受空肠管喂养的儿童都应进行多学科小组评估和随访。
    BACKGROUND: Feeding problems are common in children with complex medical problems or acute critical illness and enteral nutrition may be required. In certain situations, gastric tube feeding is poorly tolerated or may not be feasible. When feed intolerance persists despite appropriate adjustments to oral and gastric enteral regimens, jejunal tube feeding can be considered as an option for nutrition support.
    METHODS: A multidisciplinary expert working group of the Australasian Society of Parenteral and Enteral Nutrition was convened. They identified topic questions and five key areas of jejunal tube feeding in children. Literatures searches were undertaken on Pubmed, Embase, and Medline for all relevant studies, between January 2000 and September 2022 (n = 103). Studies were assessed using National Health and Medical Research Council guidelines to generate statements, which were discussed as a group, followed by voting on statements using a modified Delphi process to determine consensus.
    RESULTS: A total of 24 consensus statements were created for five key areas: patient selection, type and selection of feeding tube, complications, clinical use of jejunal tubes, follow-up, and reassessment.
    CONCLUSIONS: Jejunal tube feeding is a safe and effective means of providing nutrition in a select group of pediatric patients with complex medical needs, who are unable to be fed by gastric tube feeding. Appropriate patient selection is important as complications associated with jejunal tube feeding are not uncommon, and although mostly minor, can be significant or require tube reinsertion. All children receiving jejunal tube feeding should have multidisciplinary team assessment and follow-up.
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  • 文章类型: Journal Article
    Percutaneous endoscopic gastrostomy with jejunal extension (PEG/J) was first described in 1998 and has become the standard technique for fixing the tube in place for levodopa carbidopa intestinal gel (LCIG) infusion. The Romanian Society of Digestive Endoscopy (RSDE) decided to create a consensus paper to meet the needs in medical training and practice. After reviewing the available published data and existing recommendations, a consensus process was carried out involving the leaders of opinion in this field. The resulting text and recommendations were approved, after reaching expert consensus, and reflects the views of the RSDE for the best practice of PEG/J tube placement. The pull through method (\"pull technique\") is the prevailing PEG-tube placement procedure in Romania. The procedure can be performed with intravenous sedation combined with local anesthesia. Although minor complications are common, serious complications are infrequent, and the tube insertion procedures have a good safety record. Redo procedures are sometimes necessary and clinicians should be aware of these situations.
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  • 文章类型: Guideline
    Introduction: Neoplastic invasion of the structures of the cervical region originating from a malignant tumour developed in one of the viscera of the throat may benefit from cervical exenteration. Defined as resection of the hypopharynx, cervical oesophagus, larynx and cervical trachea, exenteration has limited indications and is mandatorily accompanied by digestive tube reconstruction. The aim of this article is to highlight the indication, surgical strategy and important surgical stages illustrated by images from personal professional experience.
    METHODS: Pharyngo-laryngo-oesophageal en bloc resection and radical cervical lymphadenectomy were followed by reconstruction via free jejunal transfer or colic pedicle grafting. Between 2000 and 2018 we have performed cervical exenteration in 25 patients with tumours originating in the pharynx, larynx or cervical oesophagus. In the cases of 5 patients in whom we did not obtain the oncological safety margin for oesophageal cancer we performed transhiatal pharyngo-laryngo-oesophagectomy. In these patients, we performed reconstruction of the oesophagus with colonic graft. In 20 cases we performed jejunal autotransplant. Results: We recorded 4 perioperative deaths, due to major arterial vessel haemorrhage (1 case), after jejunal necrosis (2 cases), and mediastinitis after oesophageal striping and colonic graft necrosis (1 case). One patient presented tumour recurrence at the level of the tracheal stump. Survival rate varied between 6 months and 4 years for the group of patients who presented for postoperative follow-ups. Conclusions: Cervical exenteration remains an option for tumour recurrence after radiochemotherapy or for obstructive airway or digestive tract tumours. It can be burdened by complications difficult to treat. The surgical team has to adapt its initial surgical strategy to the reality of the surgical field, both in terms of exeresis and in terms of types of pharyngo-oesophageal reconstruction.
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  • 文章类型: Consensus Development Conference
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  • 文章类型: Consensus Development Conference
    空肠高分化神经内分泌肿瘤(NET),回肠,和阑尾也统称为中肠类癌。类似于一般的NET,中肠NETs的诊断发病率正在上升。其呈现的症状取决于阶段和主要部位。局部区域NETs通常表现为模糊和非特异性症状。经典类癌综合征更容易出现在疾病晚期患者中。应尽可能切除小肠的局部区域NET。除了附录中的小的分化良好的NET,中肠的NETs在切除后有很大的复发风险,需要随访至少7年。中肠的转移性/晚期NETs无法治愈。优化管理需要多学科方法。生长抑素类似物可有效治疗类癌综合征。奥曲肽长效释放剂最近也被证明可以延缓疾病进展。肝定向治疗和手术减积可以改善选定患者的生活质量。针对血管内皮生长因子的贝伐单抗和针对mTOR(哺乳动物雷帕霉素靶标)的依维莫司的关键3期研究正在进行中,并可能导致改善的结果。还需要对肽受体放射疗法等新方法进行进一步研究。
    Well-differentiated neuroendocrine tumors (NETs) of the jejunum, ileum, and appendix are also collectively known as midgut carcinoids. Similar to NETs in general, the diagnosed incidence of the midgut NETs is on the rise. Their presenting symptoms vary depending on stage and primary site. Local-regional NETs often present with vague and nonspecific symptoms. Classic carcinoid syndrome is more likely to appear in patients with advanced disease. Local-regional NETs of the small bowel should be resected whenever possible. With the exception of small well-differentiated NETs of the appendix, NETs of the midgut have substantial risk of relapse after resection and need to be followed for at least 7 years.Metastatic/advanced NETs of the midgut are incurable. Optimal management requires a multidisciplinary approach. Somatostatin analogs are effective in the management of carcinoid syndrome. Octreotide long-acting release has also recently been shown to delay disease progression. Liver-directed therapy and surgical debulking can improve quality of life in selected patients. Pivotal phase 3 studies with bevacizumab targeting vascular endothelial growth factor and everolimus targeting mTOR (mammalian target of rapamycin) are ongoing and may lead to improved outcome. Further studies of novel approaches such as peptide receptor radiotherapy are also warranted.
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    文章类型: Journal Article
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    文章类型: Journal Article
    从1968年到1983年,有123例患者被诊断为胰腺炎;在28例患者中出现了假性囊肿。为了评估手术治疗的结果,进行了文献研究和图表综述。从这项研究中,我们得出结论,直径为4厘米或更小的假性囊肿的无症状患者最初可以进行预期治疗。如果假性囊肿直径大于4厘米,并且在囊肿没有自发消退趋势的情况下,手术干预似乎是强制性的。如果没有并发症发生,手术推迟至观察6周,以使囊肿成熟并促进膀胱肠吻合术。在与腹部钝性外伤有关的假性囊肿中,应进行内镜逆行胰胆管造影术(ERCP).如果ERCP显示主要导管病变,应该考虑切除。
    From 1968 to 1983 123 patients were admitted with a diagnosis of pancreatitis; in 28 patients a pseudocyst developed. To evaluate results of surgical therapy a study of the literature and a chart review were performed. From this study we conclude that asymptomatic patients with a pseudocyst of 4 cm or less in diameter can initially be treated expectantly. If the pseudocyst is larger than 4 cm in diameter and in those cases where the cyst shows no tendency to spontaneous resolution, operative intervention seems mandatory. If no complications occur, surgery is postponed until six weeks\' observation to allow maturation of the cyst and facilitate cystenteric anastomosis. In pseudocysts related to blunt abdominal trauma, endoscopic retrograde cholangiopancreatography (ERCP) should be performed. If ERCP reveals a major duct lesion, resection should be considered.
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    文章类型: Congress
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  • 文章类型: Journal Article
    The association of tuberculosis after gastrectomy is well documented. Two case reports of tuberculosis developing after jejunoileal bypass for massive obesity are presented, with a review of five previously reported cases. Four of the seven reported patients had tuberculosis infection at extrapulmonary sites. Initial symptoms included fever and acceleration of weight loss. The mean time elapsed from the time of the operation to the diagnosis of tuberculosis was 16 months. Guidelines are given for monitoring patients undergoing jejunoileal bypass with tuberculin skin tests. Indications for isoniazid prophylaxis and multiple drug chemotherapy are given. Serum concentrations of oral antituberculosis drugs must be monitored to ensure adequate absorption.
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    文章类型: Journal Article
    A systematic approach to the management of patients with pancreatic abscess is presented. The method includes an aggressive diagnostic approach relying on radiographic and ultrasound examinations, adequate transperitoneal drainage of the abscess, coupled with gastrostomy and feeding jejunostomy. The importance of nutritional support using an elemental diet administered through a jejunostomy is emphasized.
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