functional movement disorder

功能性运动障碍
  • 文章类型: Systematic Review
    可穿戴设备和远程医疗越来越多地用于跟踪患者人群中与健康相关的参数。由于步态和姿势控制缺陷导致患有运动障碍和多发性硬化症的人的活动缺陷,我们认为,评估远程医疗设备对此类患者的步态和姿势监测很有趣。
    对于本系统综述,我们搜索了电子数据库MEDLINE(PubMed),Scopus,科克伦图书馆,和SPORTDiscus。在检索到的452条记录中,12符合纳入/排除标准。关于(1)研究特征和临床方面的数据,(2)技术,(3)检索到远程监测和远程咨询,对这些研究进行了质量评估。
    所有研究涉及帕金森病患者;大多数使用三轴加速度计进行一般评估(n=4),运动波动评估(n=3),下降(n=2),和转向(n=3)。传感器的放置和计数在研究中差异很大。9个使用实验室验证的算法进行数据分析。只有一个讨论了同步患者反馈和异步远程咨询。
    可穿戴设备可实现真实世界的患者监测,并为与潜在步态障碍相关的症状和行为提供生物标志物。从而丰富临床评估和个性化治疗方案。随着数字医疗的发展,需要进一步的研究来提高设备的准确性,评估用户可接受性,并将这些工具整合到远程医疗基础设施中。
    UNASSIGNED: Wearable devices and telemedicine are increasingly used to track health-related parameters across patient populations. Since gait and postural control deficits contribute to mobility deficits in persons with movement disorders and multiple sclerosis, we thought it interesting to evaluate devices in telemedicine for gait and posture monitoring in such patients.
    UNASSIGNED: For this systematic review, we searched the electronic databases MEDLINE (PubMed), SCOPUS, Cochrane Library, and SPORTDiscus. Of the 452 records retrieved, 12 met the inclusion/exclusion criteria. Data about (1) study characteristics and clinical aspects, (2) technical, and (3) telemonitoring and teleconsulting were retrieved, The studies were quality assessed.
    UNASSIGNED: All studies involved patients with Parkinson\'s disease; most used triaxial accelerometers for general assessment (n = 4), assessment of motor fluctuation (n = 3), falls (n = 2), and turning (n = 3). Sensor placement and count varied widely across studies. Nine used lab-validated algorithms for data analysis. Only one discussed synchronous patient feedback and asynchronous teleconsultation.
    UNASSIGNED: Wearable devices enable real-world patient monitoring and suggest biomarkers for symptoms and behaviors related to underlying gait disorders. thus enriching clinical assessment and personalized treatment plans. As digital healthcare evolves, further research is needed to enhance device accuracy, assess user acceptability, and integrate these tools into telemedicine infrastructure.
    UNASSIGNED: CRD42022355460.
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  • 文章类型: Systematic Review
    背景:功能性运动障碍(FMD),一种功能性神经紊乱,是与神经科协商的常见原因。物理治疗对这些患者运动康复的功效已得到广泛研究。这篇综述的目的是分析物理治疗对运动症状的影响的现有证据,活动(步态,移动性,balance),感知健康,生活质量,以及口蹄疫患者的认知/情绪状态。
    方法:本综述遵循PRISMA的建议。搜索了四个电子数据库以查找相关文章。我们的综述包括随机对照试验,研究作为多学科方法的一部分,单独或与其他治疗相结合的专门物理治疗干预的效果。与标准物理治疗的结果进行比较。
    结果:我们回顾了4项研究,共188名患者。我们收集了研究人群的数据,结果衡量标准,协议,和结果。根据牛津质量评分系统,3项研究的方法学质量中等(3-4/5),其余研究的方法学质量较差(<3)。
    结论:物理治疗可改善运动症状,活动,感知健康,和FMD患者的生活质量。
    BACKGROUND: Functional movement disorder (FMD), a type of functional neurological disorder, is a common reason for consultation with the neurology department. The efficacy of physiotherapy for motor rehabilitation of these patients has been widely studied. The aim of this review is to analyse the available evidence on the effects of physiotherapy on motor symptoms, activity (gait, mobility, balance), perceived health, quality of life, and the cognitive/emotional state of patients with FMD.
    METHODS: This review follows the PRISMA recommendations. Four electronic databases were searched for relevant articles. Our review included randomised controlled trials investigating the effects of a specialised physiotherapy intervention alone or in combination with other therapies as part of a multidisciplinary approach, with results compared against standard physiotherapy.
    RESULTS: We reviewed 4 studies, including a total of 188 patients. We gathered data on the study population, outcome measures, protocols, and results. According to the Oxford quality scoring system, 3 studies had moderate methodological quality (3-4/5) and the remaining study presented poor methodological quality (< 3).
    CONCLUSIONS: Physiotherapy improves motor symptoms, activity, perceived health, and quality of life in patients with FMD.
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  • 文章类型: Journal Article
    功能性运动障碍(FMD)可以通过肢体无力来识别,步态障碍,或者与神经系统诊断不一致的不自主运动。尽管这些症状普遍存在,对于治疗模式几乎没有共识.本范围审查旨在确定探索心理干预治疗口蹄疫疗效的文献。作为独立干预或作为多学科团队方法的一部分。考虑纳入在成人住院和门诊环境中进行的研究。最终审查包括33篇论文;13篇仅审查心理治疗,和20审查包括心理干预在内的多学科方法。这篇文献综述重申了口蹄疫治疗的不一致性,尽管确定了近年来MDT方法的趋势。审查还确定了方法一致性可能对未来研究有益的领域,为了提高结果的有效性,以进行更大的治疗比较。有一些有希望的结果支持继续进行跨学科的调查,协作式护理方法,减少症状。
    Functional Movement Disorders (FMD) can be identified by limb weakness, gait disorders, or involuntary movements which are inconsistent with a neurological diagnosis. Despite the prevalence of such symptoms, there has been little consensus on models for treatment. This scoping review set out to identify the literature exploring the efficacy of psychological interventions for the treatment of FMD, either as a stand-alone intervention or as part of a multi-disciplinary team approach. Studies set in an adult inpatient and outpatient setting were considered for inclusion. The final review consisted of 33 papers; 13 reviewing psychological treatments only, and 20 reviewing multidisciplinary approaches that included a psychological intervention. This review of the literature reaffirms the inconsistency across treatment for FMD, although identifies a trend towards an MDT approach in recent years. The review also identifies areas where consistency in methodology may be beneficial in future research, in order to improve the validity of results for greater comparison of treatments. There are promising outcomes that support the continued investigation focused on an interdisciplinary, collaborative approach to care, for the reduction of symptoms.
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  • 文章类型: Journal Article
    Functional neurological (conversion) disorder (FND) is a prevalent and disabling condition at the intersection of neurology and psychiatry. Advances have been made in elucidating an emerging pathophysiology for motor FND, as well as in identifying evidenced-based physiotherapy and psychotherapy treatments. Despite these gains, important elements of the initial neuropsychiatric assessment of functional movement disorders (FND-movt) and functional limb weakness/paresis (FND-par) have yet to be established. This is an important gap from both diagnostic and treatment planning perspectives. In this article, the authors performed a narrative review to characterize clinically relevant variables across FND-movt and FND-par cohorts, including time course and symptom evolution, precipitating factors, medical and family histories, psychiatric comorbidities, psychosocial factors, physical examination signs, and adjunctive diagnostic tests. Thereafter, the authors propose a preliminary set of clinical content that should be assessed during early-phase patient encounters, in addition to identifying physical signs informing diagnosis and potential use of adjunctive tests for challenging cases. Although clinical history should not be used to make a FND diagnosis, characteristics such as acute onset, precipitating events (e.g., injury and surgery), and a waxing and waning course (including spontaneous remissions) are commonly reported. Active psychiatric symptoms (e.g., depression and anxiety) and ongoing psychosocial stressors also warrant evaluation. Positive physical examination signs (e.g., Hoover\'s sign and tremor entrainment) are key findings, as one of the DSM-5 diagnostic criteria. The neuropsychiatric assessment proposed emphasizes diagnosing FND by using \"rule-in\" physical signs while also considering psychiatric and psychosocial factors to aid in the development of a patient-centered treatment plan.
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  • 文章类型: Journal Article
    The aim of this scoping review is to describe the characteristics of patients requiring admission to hospital for functional neurological disorder (FND), assess interventions provided, and evaluate outcomes in the context of acute hospital presentation or elective admission with chronic symptoms (>3 months).
    A scoping review was performed. Included articles described adult patients admitted with FND to an inpatient care setting. Articles focusing on psychogenic non-epileptic attacks (PNEA) were excluded.
    The search strategy identified 1963 citations. A total of 34 articles met inclusion criteria, with 458 patients (66% female) described. The pooled mean age of patients in all studies was 40.6 years. Eleven studies described patients with acute presentation, and 16 studies described patients with chronic FND symptoms admitted to the hospital. Motor symptoms were most common. Interventions were most commonly physiotherapy and psychotherapy. Most studies reported partial or complete resolution of symptoms.
    This scoping review summarizes the literature on the characteristics of patients admitted to the hospital, both with acute and chronic symptoms, for inpatient treatment of FND. When comparing patients with acute to those with chronic symptoms, we found that acute presentations were older (46.9 vs. 43.7 years) and had a higher representation of men (33% vs. 30%). Those presenting with chronic symptoms were more likely to not improve or relapse. We postulate that early diagnosis and inpatient rehabilitation could have a positive impact on outcomes for patients with FND.
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  • 文章类型: Journal Article
    BACKGROUND: Functional movement disorders are common and disabling neurologic conditions. Patients with functional neurologic disorders represent a large proportion of neurology clinic referrals, and limited availability of subspecialty care creates a considerable burden for the healthcare system. These conditions are currently treated with a combination of physical therapy and cognitive behavioral therapy, with variable success.
    METHODS: We searched the Medline database for studies on the epidemiology and physiology of functional movement disorders, as well as those on the placebo effect in movement disorders. We reviewed and summarized the literature on these topics and explored ethical issues concerning the administration of placebos to patients with functional movement disorders.
    RESULTS: Studies of placebos, particularly in patients with movement disorders, have shown that these \"inert\" agents can provide demonstrable neurophysiologic benefits, even in open-label studies. Physician surveys have shown that many administer placebos for diagnostic and therapeutic purposes, although there are ethical concerns about this practice. We used a principle-based approach and reviewed ethical arguments for (justice and beneficence) and against (non-maleficence and autonomy) the use of placebos in functional movement disorders. In this context, we argue for the importance of the therapeutic alliance in preserving patient autonomy while exploring the potential benefits of placebo therapy.
    CONCLUSIONS: An ethical argument is presented in support of nondeceptive clinical placebo use for the treatment of functional movement disorders. Patient and clinician attitudes regarding the use of placebos should be investigated before placebo-therapy trials are conducted.
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  • 文章类型: Journal Article
    Functional parkinsonism (FP) is considered rare but no studies have looked at its frequency. Case series have described high rates of comorbidity with Parkinson\'s disease (PD), suggesting a possible association between these conditions.
    To study the prevalence, epidemiology and clinical features of FP and its association with PD.
    We conducted a cross-sectional population-based prevalence study as well as a chart review of cases who received a diagnosis of FP over a 10-year-period in two movement disorder clinics in Switzerland. Epidemiological data regarding FP features were collected. The co-occurrence of PD, psychiatric disorders and other functional disorders were recorded. Clinical differences between FP and FP+PD groups are presented and discussed in light of a literature review.
    The crude prevalence of FP was 0.64 per 100,000 in our population. FP represented 0.24% of patients with parkinsonism. Among 12 FP cases, female gender predominance (87%), mean age of onset of 45.5(±13.3 Standard deviation SD) years and prolonged diagnostic delay (mean 59±75 SD months) was found. Six patients had an additional diagnosis of PD, 83% of depression and 66% of other functional neurological disorder. In four patients with FP+PD, FP preceded PD by 6 to 56months.
    These results suggest that FP should be considered in the differential diagnosis of patients presenting with parkinsonism. The high rate of co-occurrence with PD emphasizes the importance of long-term follow up of these patients. The observation that FP often precedes PD should be verified in prospective studies.
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