周围性面神经麻痹的发病率呈上升趋势,由于可见的症状,心理问题会影响生活质量。因此,患者报告的结局指标对于从患者角度评估周围性面神经麻痹的疾病负担和治疗效果至关重要.本研究调查了影响患者整体变化印象(PGIC)评分的因素,一种患者报告的结果测量,在周围性面神经麻痹住院患者中。这项回顾性研究分析了韩国医院收治的200名周围性面神经麻痹患者的电子病历,KyungHee大学医学中心,2022年5月1日至2023年4月30日。人口的影响,电生理学,干预,并对PGIC评分的临床因素进行评价。描述性统计显示,住院时间(P=0.020),从发病到住院的时间(P=0.022),泪道障碍(P=0.002),在入院时(P=.016)和出院时(P<.001)评估的House-Brackmann(HB)等级,从入院到出院的HB等级改善(P=0.002),出院时面部总残疾指数(FDI)评分(P<.001)与PGIC评分显著相关。在多变量逻辑回归分析中,入院时HB等级(OR:13.89,95%CI:2.18-113.60),住院时间(OR:0.27,95%CI:0.07-0.92),从发病到住院的时间(OR:5.55,95%CI:1.36-24。77),泪液相关症状(OR:0.41,95%CI:0.17-0.96),外国直接投资总分(OR:0.45,95%CI:0.20-0.98),出院时HB等级改善大于入院时(OR:0.08,95%CI:0.02-0.31)与PGIC评分显著相关.初始疾病严重程度较轻的患者,住院时间超过7天,从发病到住院的时间更短,改善泪腺症状,FDI总分,入院和出院之间的HB等级在周围性面神经麻痹中经历了更显著的主观改善。
The incidence of peripheral facial palsy is on the rise, with psychological issues influencing quality of life due to visible symptoms. Consequently, patient-reported outcome measures are critical in assessing the disease burden and the treatment efficacy of peripheral facial palsy from patients\' perspective. This study examines factors influencing patients\' global impression of change (PGIC) scores, a type of patient-reported outcome measure, in hospitalized patients with peripheral facial palsy. This retrospective study analyzed the electronic medical records of 200 patients with peripheral facial palsy who were admitted to the Korean Medicine Hospital, Kyung Hee University Medical Center from May 1, 2022 to April 30, 2023. Impact of demographic, electrophysiological, intervention, and clinical factors on PGIC scores were evaluated. Descriptive statistics showed that the length of hospitalization (P = .020), time from disease onset to hospitalization (P = .022), lacrimal disorders (P = .002), House-Brackmann (HB) grade evaluated at admission (P = .016) and at discharge (P < .001), improvement in HB-grade from admission to discharge (P = .002), and total facial disability index (FDI) score at discharge (P < .001) were significantly associated with PGIC scores. In multivariate logistic regression analysis, HB-grade at admission (OR: 13.89, 95% CI: 2.18-113.60), length of stay (OR: 0.27, 95% CI: 0.07-0.92), time from disease onset to hospitalization (OR: 5.55, 95% CI: 1.36-24. 77), tear-related symptoms (OR: 0.41, 95% CI: 0.17-0.96), total FDI score (OR: 0.45, 95% CI: 0.20-0.98), and greater improvement in HB-grade at discharge compared to admission (OR: 0.08, 95% CI: 0.02-0.31) were significantly associated with PGIC scores. Patients with milder initial disease severity, hospitalization period exceeding 7 days, shorter time from disease onset to hospitalization, improvement of lacrimal symptoms, total FDI score, and HB-grade between admission and discharge experienced more significant subjective improvement in peripheral facial palsy.