facial paralysis

面瘫
  • 文章类型: Journal Article
    面神经训练可预防周围性面瘫患者面部表情肌萎缩,促进面部对位松解术的恢复。然而,面神经训练仍然缺乏具体统一的技术标准,导致临床培训方法多样、水平参差不齐。为规范护理人员面神经功能训练技术的应用,这项研究召集了国内相关专家,结合周围性面瘫的疾病特点和专家临床经验,与专家进行了深入访谈,专家信函和专家会议,最后制定了周围性面瘫患者面神经功能训练的专家共识。总的来说,规范时机的建议,训练方法,评价方法,健康教育等方面提供参考。
    Facial nerve training can prevent facial expression muscle atrophy and promote the recovery of facial para-lysis in patients with peripheral facial paralysis. However, there is still a lack of specific and unified technical standards for facial nerve training, which results in a variety of clinical training methods and uneven levels. In order to standardize the application of facial nerve function training technology for nursing staff, the study convened relevant domestic experts, based on evidence-based combination with the disease characteristics of peripheral facial paralysis and expert clinical experience, conducted in-depth interviews with experts, expert correspondence and expert meetings, and finally formulated the expert consensus on facial nerve function training in patients with peripheral facial paralysis. Overall, suggestions for standardizing the timing, training methods, evaluation methods, health education and other aspects were provided for clinical reference.
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  • 文章类型: Journal Article
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  • 文章类型: Systematic Review
    目的:对大型前庭神经鞘瘤(VS)的单部分立体定向放射外科(SRS)专用文献进行系统回顾,最大直径≥2.5cm和/或归类为KoosIV级,并代表国际立体定向放射外科学会(ISRS)提出共识建议。
    方法:Medline和Embase数据库用于应用系统评价和荟萃分析(PRISMA)方法的首选报告项目。我们考虑了符合条件的前瞻性和回顾性研究,用英语写的,报告大型VS的治疗结果;对大型术后肿瘤的SRS进行汇总和单独分析.
    结果:最初确定的229项研究中有19项符合最终纳入标准。肿瘤控制的总体粗率为89%(在没有手术的情况下为93.7%,在先手术的情况下为87.7%)。挽救性显微外科手术切除率,需要分流,所有系列的额外SRS与没有手术的分别为9.6%和3.3%,4.7%比6.4%和1%比0.9%,分别。所有系列的面神经麻痹和听力保留率分别为1.3%对3.4%和34.2%对40.4%,分别。
    结论:UpfrontSRS导致较高的肿瘤控制率,与包括先前手术的患者在内的一系列结果相比,面神经麻痹和听力保留率可接受(C级证据)。因此,虽然大VS被认为是显微手术切除的经典适应症,在选定的患者中可以考虑前期SRS,我们建议规定的边际剂量为11~13Gy(C级证据).
    OBJECTIVE: To perform a systematic review of literature specific to single-fraction stereotactic radiosurgery (SRS) for large vestibular schwannomas (VS), maximum diameter ≥ 2.5 cm and/or classified as Koos Grade IV, and to present consensus recommendations on behalf of the International Stereotactic Radiosurgery Society (ISRS).
    METHODS: The Medline and Embase databases were used to apply the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach. We considered eligible prospective and retrospective studies, written in the English language, reporting treatment outcomes for large VS; SRS for large post-operative tumors were analyzed in aggregate and separately.
    RESULTS: 19 of the 229 studies initially identified met the final inclusion criteria. Overall crude rate of tumor control was 89% (93.7% with no prior surgery vs 87.7% with prior surgery). Rates of salvage microsurgical resection, need for shunt, and additional SRS in all series versus those with no prior surgery were 9.6% vs 3.3%, 4.7% vs 6.4% and 1% vs 0.9%, respectively. Rates of facial palsy and hearing preservation in all series versus those with no prior surgery were 1.3% vs 3.4% and 34.2% vs 40.4%, respectively.
    CONCLUSIONS: Upfront SRS resulted in high rates of tumor control with acceptable rates of facial palsy and hearing preservation as compared to the results in those series including patients with prior surgery (level C evidence). Therefore, although large VS are considered classic indication for microsurgical resection, upfront SRS can be considered in selected patients and we recommend a prescribed marginal dose from 11 to 13 Gy (level C evidence).
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    文章类型: Journal Article
    背景:贝尔麻痹是急性面神经麻痹和瘫痪的最常见原因,具有毁灭性残疾,但自发恢复率高。未完全康复的患者有可能需要进行重建手术的功能障碍。临床实践指南:贝尔氏麻痹建议使用高剂量类固醇治疗,因为它显示完全康复的可能性更高。然而,指南依从率不一致且未经研究。
    目的:确定威斯康辛大学麦迪逊分校的医院临床医生遵循推荐的临床指南并开出高剂量类固醇药物的频率。
    方法:对来自一家医院(大学医院)的图表进行审查,以评估贝尔麻痹指南的依从性。确定了从2008年到2018年所有以医院为基础的初次诊断为贝尔麻痹(ICD-9351.0和ICD-10G51.0)的患者。如果他们在1年前被诊断为贝尔麻痹(n=250)并且没有可用的药物清单(n=353),则将其排除在外。我们检查了病人的人口统计学,常见的合并症,以及任何放射科和实验室命令。
    结果:我们确定了565例主要诊断为贝尔麻痹的患者,并提供了可用的药物清单;77.70%接受了推荐的治疗。患者的中位年龄为47岁(四分位距34-59岁),52.16%为男性,82.46%由急诊医学临床医生治疗。其他治疗的临床医生是以医院为基础的初级保健,耳鼻喉科和整形外科,和其他人。多因素分析表明,治疗临床医师专业是唯一有意义的阳性预测因素。
    结论:相当一部分临床医生遵循贝尔麻痹的治疗指南。需要进一步和更大的研究来更好地确定干预点,以提高指南的依从性。
    BACKGROUND: Bell\'s palsy is the most common cause of acute facial nerve paresis and paralysis with devastating disability yet high rate of spontaneous recovery. Patients who do not fully recover have functional disability that may require reconstructive surgery. The Clinical Practice Guideline: Bell\'s Palsy recommends treatment with high-dose steroids as it shows a higher likelihood of complete recovery. However, guideline adherence rates are inconsistent and unstudied.
    OBJECTIVE: To identify the frequency at which hospital-based clinicians at the University of Wisconsin-Madison follow recommended clinical guidelines and prescribe high-dose steroid medication.
    METHODS: Charts were reviewed from a single hospital (University Hospital) to evaluate Bell\'s palsy guideline adherence. All hospital-based encounters from 2008 through 2018 with primary diagnosis of Bell\'s palsy (ICD-9 351.0 and ICD-10 G51.0) were identified. Encounters were excluded if they had a diagnosis of Bell\'s palsy within 1 year prior (n=250) and did not have a medication list available (n=353). We examined patient demographics, common comorbidities, and any radiology and lab orders.
    RESULTS: We identified 565 patients with a primary diagnosis of Bell\'s palsy with available medication lists; 77.70% received the recommended treatment. The patients\' median age was 47 (interquartile range 34-59), 52.16% were male, and 82.46% were treated by emergency medicine clinicians. Other treating clinicians were hospital-based primary care, otolaryngology and plastic surgery, and others. Multivariate analysis showed that treating clinician specialty was the only significant positive predictor.
    CONCLUSIONS: A significant portion of clinicians followed treatment guidelines for Bell\'s palsy. Further and larger research is needed to better identify points of intervention to improve guideline adherence.
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  • 文章类型: Journal Article
    背景:周围性面神经麻痹(PFP)导致患侧面部无力或瘫痪。在韩国,对韩国药物治疗PFP的需求很高。制定了韩国面神经麻痹医学的临床实践指南(CPGs);然而,仍然没有足够的证据支持韩国药物治疗的有效性和安全性.因此,本研究旨在评估基于CPGs的韩国药物治疗急性PFP的有效性和安全性.
    方法:这是一个多中心,prospective,观察性研究。参与者将从一家韩国医学医院和八家韩国医学诊所招募。参与者将接受基于CPG的韩国医学治疗,填写调查问卷,并接受电生理测试。House-Brackmann(H-B)等级的变化,嘴唇和眼睛的运动,与面部麻痹相关或伴有面部麻痹的症状,面部残疾指数,EuroQol5维5级(EQ-5D-5L),和EuroQol视觉模拟量表(EQ-VAS),和肌电图(EMG)的结果,神经电描记术(EnoG),和闪烁反射测试将被分析。对于安全分析,将记录不良事件,对于可行性分析,将评估“是否值得”问卷的结果。
    结论:我们希望根据本研究的急性PFP患者的CPG,得出韩国药物治疗有效性和安全性的真实临床数据。这将是补充和改进CPG的基础,并为临床和政策决策提供依据。
    背景:本研究获得了庆熙大学韩国医学医院机构审查委员会的批准(2021-06-005-001),并在韩国临床试验注册中心(CRIS)注册,大韩民国(KCT0006562)。
    BACKGROUND: Peripheral facial palsy (PFP) results in weakness or paralysis of the affected side of the face. In Korea, there is a high demand for Korean medicine treatment for PFP. The clinical practice guidelines (CPGs) of Korean medicine for facial palsy were developed; however, there remains insufficient evidence to support the effectiveness and safety of Korean medicine treatment. Thus, this study aimed to evaluate the effectiveness and safety of Korean medicine treatment based on the CPGs in patients with acute PFP.
    METHODS: This is a multicenter, prospective, observational study. The participants will be recruited from one Korean medicine hospital and eight Korean medicine clinics. The participants will receive Korean medicine treatments based on the CPGs, fill in survey questionnaires, and undergo electrophysiologic testing. The changes in House-Brackmann (H-B) grade, movement of the lip and eye, symptoms related to or accompanied by facial palsy, Facial Disability Index, EuroQol 5-dimension 5-level (EQ-5D-5L), and EuroQol Visual Analogue Scale (EQ-VAS), and the results of electromyography (EMG), electroneurography (ENoG), and Blink Reflex test will be analyzed. For the safety analysis, adverse events will be recorded, and for the feasibility analysis, the results of the Was It Worth It questionnaire will be assessed.
    CONCLUSIONS: We expect to draw real-world clinical data on the effectiveness and safety of Korean medicine treatment based on the CPGs in patients with acute PFP from this study. It would be the basis for complementing and improving the CPGs and provide the basis of clinical and policy decision-making.
    BACKGROUND: This study was approved by the Institutional Review Board of Kyung Hee University Korean Medicine Hospital (2021-06-005-001), and registered with the Korean Clinical Trial Registry (CRIS), Republic of Korea (KCT0006562).
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  • 文章类型: Journal Article
    UNASSIGNED: Facial paralysis can impair one\'s ability to form facial expressions that are congruent with internal emotion. This hinders communication and the cognitive processing of emotional experience. Facial reanimation surgery, which aims to restore full facial expressivity is a relatively recent undertaking which is still evolving. Due in large part to published techniques, refinements, and clinical outcomes in the scientific literature, consensus on best practice is gradually emerging, whereas controversies still exist.Taking stock of how the discipline reached its current state can help delineate areas of agreement and debate, and more clearly reveal a path forward. To do this, the authors have analyzed the 50 seminal publications pertaining to facial reanimation surgery. In longstanding cases, the free gracilis transfer emerges as a clear muscle of choice but the nerve selection remains controversial with prevailing philosophies advocating cross facial nerve grafts (with or without the support of an ipsilateral motor donor) or an ipsilateral motor donor only, of which the hypoglossal and nerve to masseter predominate. The alternative orthodoxy has refined the approach popularized by Gillies in 1934 and does not require the deployment of microsurgical principles. Although this citation analysis does not tell the whole story, surgeons with an interest in facial reanimation will find that this is a good place to start.
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  • 文章类型: Journal Article
    Unilateral peripheral facial nerve palsy jeopardizes quality of life, rendering psychological consequences such as low self-esteem, social isolation, anxiety, and depression. Among therapeutical approaches, use of Botulinum toxin type A (BoNT-A) on the nonparalyzed side has shown promising results and improvement of quality of life. Nevertheless, the correct technique is paramount, since over-injection of the muscles can result in lack of function, leading to a \"paralyzed\" appearance, and even worse, functional incompetence, which may cause greater distress to patients. Therefore, the objective of this article is to provide a practical guideline for botulinum toxin use in facial palsy. To this aim, adequate patient assessment, BoNT-A choice, injection plan and dosage, and injection techniques are covered.
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  • 文章类型: Journal Article
    贝尔麻痹,或者特发性面神经麻痹,是一种原因不明的周围性面神经麻痹,表现为突然的,面部肌肉的单侧无力。及时治疗贝尔氏麻痹是患者面部功能完全恢复的关键。诊断和管理的延迟会导致永久性面部缺陷。存在许多临床实践指南(CPG)来指导特发性面神经麻痹患者的临床决策。然而,到目前为止,尚未对这些CPG的方法严密性和质量进行全面审查。因此,作者的目的是评估现有的CPG,以确保安全和有效的做法。共有8项准则符合纳入标准,并进行了评估。只有两个CPG获得了“高”的总体评级,有五个或更多的质量领域得分>60%。在CPG上,发展的严谨性领域,利益相关者的参与,适用性总分最低,为48.1%,43.9%,和43.1%,分别。根据AGREEII文书,贝尔氏麻痹的CPG的方法学严谨和质量低到平均水平。特别是,贝尔麻痹的未来指南应该着眼于发展的严格性的质量领域,利益相关者的参与,和适用性是最大的改进机会。
    Bell\'s palsy, or idiopathic facial paralysis, is a peripheral facial palsy of unknown cause that presents as sudden, unilateral weakness of the muscles of the face. Prompt treatment of Bell\'s palsy is critical in order for patients to achieve complete recovery of facial function. Delays in diagnosis and management can result in permanent facial defects. A number of clinical practice guidelines (CPG) exist to guide clinical decision-making in patients presenting with idiopathic facial paralysis. However, to date, there has been no comprehensive review of the methodological rigor and quality of these CPGs. Thus, the objective of the authors is to appraise the existing CPGs to ensure safe and effective practices. A total of eight guidelines met the inclusion criteria and were appraised. Only two CPGs achieved an overall rating of \'High\', having five or more quality domains scoring > 60%. Across the CPGs, the domains of rigor of development, stakeholder involvement, and applicability has the lowest overall scores with 48.1%, 43.9%, and 43.1%, respectively. Based on the AGREE II instrument, the methodological rigor and quality of CPGs for Bell\'s palsy is low to average. In particular, future guidelines for Bell\'s palsy should look to the quality domains of rigor of development, stakeholder involvement, and applicability as the greatest opportunities for improvement.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    The American Academy of Otolaryngology-Head and Neck Surgery has published clinical practice guidelines (CPGs) to guide management of common otolaryngologic (ENT) conditions. While these CPGs have been disseminated within specialty journals, many patients\' first presentation of certain ENT complaints is to primary and acute care settings, including the emergency department (ED). It is less clear whether practice in these settings is concordant with specialty CPGs.
    Retrospective cohort study.
    A retrospective review of medical records was performed at an academic tertiary care center with ED diagnoses of 1) Bell\'s palsy/facial weakness (BP) or 2) acute otitis externa (AOE) from May 2014-June 2018. Individual chart abstraction was performed for all encounters with these diagnoses for the purpose of assessing providers\' adherence to CPGs.
    During the study period, 224 patients were diagnosed with BP and 465 patients were diagnosed with AOE. Of the patients diagnosed with BP, 94% (n = 211/224) were prescribed oral steroids, concordant with guidelines, while 36% of these patients received head computed tomography (CT) scans and 43% received laboratory tests, counter to the guidelines. For those with a diagnosis of AOE, 28.6% received topical antibiotics only as primary treatment (n = 133/465) in accordance with guidelines while systemic antibiotics were prescribed in 42.2% (n = 196/465) discordant with the guidelines and 29.2% received both topical and systemic antibiotics (n = 136/465).
    CPGs developed by subspecialty societies provide evidence-based recommendations for the care of patients with particular conditions, but may not be disseminated broadly outside of the specialty. Further research is required to understand the reasons behind divergent management of such conditions.
    3 Laryngoscope, 131:1266-1270, 2021.
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