■运动过程中的体力消耗通常会导致氧化应激和炎症反应增加,显著影响物理性能。目前减轻这些影响的策略受到其有效性和潜在副作用的限制。分子氢(H2)因其抗氧化和抗炎特性而受到关注。研究表明,补充H2有助于在运动过程中的抗氧化潜力和抗疲劳,但是这些研究中的观察和研究方案存在差异。
■本系统综述和荟萃分析旨在全面表征补充H2对身体表现的影响(即,耐力,肌肉力量,和爆炸力),提供可以使用H2提高物理性能的策略的知识。
■我们对六个数据库进行了文献检索(PubMed,WebofScience,Medline,运动铁饼,Embase,和PsycINFO)根据PRISMA指南。从纳入的研究中提取数据并转化为标准化平均差(SMD)。之后,我们进行了随机效应荟萃分析,并使用I2统计量评估异质性.建议评估的分级,发展,和评估(GRADE)用于评估从该荟萃分析获得的证据的质量。
■总共,纳入了由597名参与者组成的27份出版物。搜索最终包括有氧耐力,无氧耐力,肌肉力量,下肢爆发力,感知努力(RPE)评级,血乳酸(BLA),和效应大小(ES)合成中的平均心率(HRavg)。H2对有氧耐力的ES,包括V²O2max(SMD=0.09,p=0.394;I2=0%)和有氧耐力运动(SMD=0.04,p=0.687;I2=0%),不显着和微不足道;H2在30s最大无氧耐力(SMD=0.19,p=0.239;I2=0%)上的ES不显着且微不足道;H2对肌肉力量的ES(SMD=0.19,p=0.265;I2=0%)不显著且微不足道;但H2对下肢爆发力的ES(SMD=0.30,p=0.018;I2=0%)较小,并且显此外,H2降低运动期间的RPE(SMD=-0.37,p=0.009;I2=58.0%)和BLA(SMD=-0.37,p=0.001;I2=22.0%),但不是HRavg(SMD=-0.27,p=0.094;I2=0%)。
■这些研究结果表明,补充H2有利于健康成人提高下肢爆发力,缓解疲劳,提高BLA间隙,但可能无法有效提高有氧和无氧耐力和肌肉力量。因此,需要进行更严格设计的未来研究来检查和确认H2对人类这些重要功能的影响。
■http://www.crd.约克。AC.英国/PROSPERO。
UNASSIGNED: Physical exertion during exercise often leads to increased oxidative stress and inflammatory responses, significantly affecting physical performance. Current strategies to mitigate these effects are limited by their effectiveness and potential side effects. Molecular hydrogen (H₂) has gained attention for its antioxidant and anti-inflammatory properties. Studies have suggested that H2 supplementation contributes to antioxidant potential and anti-fatigue during exercise, but the variance in the observations and study protocols is presented across those studies.
UNASSIGNED: This systematic
review and meta-analysis aimed to comprehensively characterize the effects of H₂ supplementation on physical performance (i.e., endurance, muscular strength, and explosive power), providing knowledge that can inform strategies using H2 for enhancing physical performance.
UNASSIGNED: We conducted a literature search of six databases (PubMed, Web of Science, Medline, Sport-Discus, Embase, and PsycINFO) according to the PRISMA guidelines. The data were extracted from the included studies and converted into the standardized mean difference (SMD). After that, we performed random-effects meta-analyses and used the I 2 statistic to evaluate heterogeneity. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to assess the quality of the evidence obtained from this meta-analysis.
UNASSIGNED: In total, 27 publications consisting of 597 participants were included. The search finally included aerobic endurance, anaerobic endurance, muscular strength, lower limb explosive power, rating of perceived exertion (RPE), blood lactate (BLA), and average heart rate (HRavg) in the effect size (ES) synthesis. The ES of H2 on aerobic endurance, including V̇O2max (SMD = 0.09, p = 0.394; I 2 = 0%) and aerobic endurance exercise (SMD = 0.04, p = 0.687; I 2 = 0%), were not significant and trivial; the ES of H2 on 30 s maximal anaerobic endurance (SMD = 0.19, p = 0.239; I 2 = 0%) was not significant and trivial; the ES of H2 on muscular strength (SMD = 0.19, p = 0.265; I 2 = 0%) was not significant and trivial; but the ES of H2 on lower limb explosive power (SMD = 0.30, p = 0.018; I 2 = 0%) was significant and small. In addition, H2 reduces RPE (SMD = -0.37, p = 0.009; I 2 = 58.0%) and BLA (SMD = -0.37, p = 0.001; I 2 = 22.0%) during exercise, but not HRavg (SMD = -0.27, p = 0.094; I 2 = 0%).
UNASSIGNED: These findings suggest that H2 supplementation is favorable in healthy adults to improve lower limb explosive power, alleviate fatigue, and boost BLA clearance, but may not be effectively improving aerobic and anaerobic endurance and muscular strength. Future studies with more rigorous designs are thus needed to examine and confirm the effects of H2 on these important functionalities in humans.
UNASSIGNED: http://www.crd.york.ac.uk/PROSPERO.