clinical effect

临床效果
  • 文章类型: Journal Article
    目的:本研究的目的是评估后路减压的效果,融合固定术治疗脊柱痛风。脊柱痛风是一种累及脊柱的痛风性关节炎,会影响脊柱的所有部分。目前,脊髓痛风的病因和发病机制尚不清楚,目前还没有明确的治疗脊髓痛风的方法。
    方法:这是一个由7名患者(7名男性)接受后路减压的病例系列,2016年1月至2020年1月,融合固定术治疗脊柱痛风。体格检查,射线照相术,CT,MRI,使用日本骨科协会(JOA)评分和视觉模拟量表(VAS)评分来评估该程序的效果。所有患者每3个月随访一次。评价时间点为术后12个月。使用SPSS22.0(IBM,Armonk,NY,美国)。
    结果:术前JOA评分为13.43±6.55,VAS评分为7.43±1.51。术后12个月,JOA评分为24.43±3.74,VAS评分为0.86±0.90。手术后12个月,与手术前相比,JOA和VAS评分显著改善(分别为P=0.004和P=0.002).所有患者均未因积极合理控制尿酸而再次进行痛风手术。未报告螺钉松动或移位。只有一个螺钉尾盖松开。影像学检查显示痛风无明显积聚或周围骨质破坏,节段不稳定性明显改善。7例患者的神经症状没有进行性加重。
    结论:后入路减压,融合和固定可以稳定椎体,去除痛风,直接解除局部脊髓压迫。该方法是治疗脊髓痛风的可靠手术选择。
    OBJECTIVE: The aim of the present study was to assess the effect of posterior decompression, fusion and fixation in the treatment of spinal gout. Spinal gout is a disease of gouty arthritis involving the spine, which can affect all segments of the spine. At present, the etiology and pathogenesis of spinal gout are not clear, and there are no definite methods for the treatment of spinal gout.
    METHODS: This was a case series of seven patients (seven men) who underwent posterior decompression, fusion and fixation in the treatment of spinal gout between January 2016 and January 2020. Physical examination, radiography, CT, MRI, Japanese Orthopaedic Association (JOA) score and visual analog scale (VAS) score were used to evaluate the effect of this procedure. All patients were followed up every 3 months. The evaluation time point was 12 months after the operation. Comparisons of the functional indexes of the patients before and after the operation were performed using SPSS 22.0 (IBM, Armonk, NY, USA).
    RESULTS: The JOA score was 13.43 ± 6.55 and the VAS score was 7.43 ± 1.51 preoperatively. The JOA score was 24.43 ± 3.74 and the VAS score was 0.86 ± 0.90 postoperatively at 12 months after surgery. At 12 months after surgery, the JOA and VAS score showed significant improvements when compared with those before surgery (P = 0.004 and P = 0.002, respectively). None of the patients had re-surgery of the gout due to actively and reasonably controlling uric acid. No loosening or displacement of screws was reported. There was only one screw tail cap loosening. Radiographic examination revealed that there was no obvious accumulation of gout or surrounding bone destruction, and the segmental instability was significantly improved. There was no progressive aggravation of neurological symptoms of the seven patients.
    CONCLUSIONS: Posterior approach decompression, fusion and fixation can stabilize the vertebral body, remove gout and directly relieve local spinal cord compression. The method is a reliable surgical choice for the treatment of spinal gout.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    未经证实:皮肤肿物是邻近多个毛囊及其周围组织的化脓性感染,主要由金黄色葡萄球菌引起。皮肤胀痛常发生在颈部,后面,和其他皮肤较厚的部分。它还可以扩散到皮下组织并引起广泛的皮下感染。尤其常见于免疫力低下的人,如糖尿病,肾炎,和营养不良。
    未经证实:我们报告了4例颈部的龟裂,其中3例采用火针结合外用药物的中药治疗,另一个是通过手术切开和引流治疗,清创术,和换衣服。
    UNASSIGNED:所有四个病例均取得了良好的治疗效果。结果表明,在治疗早期的carb,与手术治疗相比,火针疗法创伤较小,预后疤痕较小,成本较低,更快的恢复。然而,当碳体明显扩张或晚期碳体的深层组织显示糜烂坏死时,手术清创是必要的。
    UNASSIGNED:以火针为基础的中医疗法对于早期治疗龟裂具有重要的临床意义,这是值得进一步研究的。
    UNASSIGNED: Skin carbuncle is a suppurative infection of adjacent multiple hair follicles and their surrounding tissues, mostly caused by Staphylococcus aureus. Skin carbuncle often occurs in the neck, the back, and other skin thicker parts. It can also spread to the subcutaneous tissue and cause extensive subcutaneous infection. It is especially common in people with low immunity such as diabetes, nephritis, and malnutrition.
    UNASSIGNED: We reported four cases of carbuncle of the neck, three of which were treated with traditional Chinese medicine therapy based on fire needles combined with topical drugs, and the other one was treated by surgical incision and drainage, debridement, and dressing change.
    UNASSIGNED: All four cases achieved good therapeutic effects. The results showed that in the treatment of early carbuncle, compared with surgical treatment, fire needle therapy had less trauma, smaller prognosis scar, less cost, and faster recovery. However, when the carbuncle significantly expands or the deep tissue of the late carbuncle shows erosion necrosis, surgical debridement is necessary.
    UNASSIGNED: The traditional Chinese medicine therapy based on the fire needle for the early treatment of carbuncle has important clinical significance, which is worthy of further study.
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  • 文章类型: Journal Article
    This paper deals with the problem of overlapping clinical effects of neurotropic agents in treating children with complex comorbidity. An 8-year-old boy suffering from a complexity of symptoms such as chronic motor tics, compulsions, phobias, anxious inhibition, and stuttering displayed the totality of Tourette\'s syndrome while taking imipramine. Sulpiride also enhanced motor and vocal tics. In the discussion, a review on the neurometabolic mechanisms in tic disease actually known is given, and on drugs proven to precipitate tics, which is the case in a number of neurotropic agents. Psychodynamics and famility dynamics are another issue to be regarded independently.
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