chondroma

软骨瘤
  • 文章类型: Case Reports
    软组织软骨瘤很少见,良性软骨肿瘤主要影响四肢,通常在没有明确性别偏爱的中年人中被诊断出来。尽管它们是良性的,由于生长缓慢,这些肿瘤可能会带来重大的诊断挑战,无症状性质,和模仿其他软组织肿瘤的潜力。
    我们报告一例27岁的男性,有8年的历史,在左脚第二脚趾的背侧有逐渐扩大的肿块,导致疼痛,行走困难,穿着鞋子。初步临床检查显示,患处无触痛肿胀,感觉减退。影像学检查结果表明软组织肿块伴有点状钙化,而磁共振成像显示,毗邻但并非由骨骼引起的信号强度病变较大。细针穿刺细胞学检查提示良性混合性肿瘤/软骨样汗管瘤。进行了切除活检,显示一个界限清楚的肿瘤,具有成熟透明软骨的小叶,与软组织软骨瘤的诊断一致。术后恢复顺利,除了局部皮瓣坏死通过植皮治疗。随访1年无复发。
    软组织软骨瘤,虽然罕见且良性,会显著影响患者的生活质量。正确诊断,包括全面评估和组织病理学确认,对于有效管理和预防不必要的干预措施至关重要。这个案例增加了对临床表现的宝贵见解,诊断挑战,软组织软骨瘤的管理策略。
    UNASSIGNED: Soft-tissue chondromas are rare, benign cartilaginous tumors predominantly affecting the extremities, often diagnosed in middle-aged individuals without a clear sex predilection. Despite their benign nature, these tumors can pose significant diagnostic challenges due to their slow growth, asymptomatic nature, and potential for mimicking other soft-tissue tumors.
    UNASSIGNED: We report a case of a 27-year-old male with an 8-year history of a progressively enlarging mass on the dorsal aspect of the second toe of the left foot, leading to pain, difficulty in walking, and wearing shoes. Initial clinical examination revealed a firm, non-tender swelling with hypoesthesia over the affected area. Radiographic findings suggested a soft-tissue mass with stippled calcification, while magnetic resonance imaging indicated a large altered signal intensity lesion abutting but not arising from the bone. Fine needle aspiration cytology hinted at a benign mixed tumor/chondroid syringoma. An excisional biopsy was performed, revealing a well-circumscribed tumor with lobules of mature hyaline cartilage, consistent with a diagnosis of soft-tissue chondroma. Post-operative period recovery was uneventful except for local flap necrosis which was managed with skin grafting. There was no recurrence at the 1-year follow-up.
    UNASSIGNED: Soft-tissue chondromas, while rare and benign, can significantly impact patients\' quality of life. Correct diagnosis, involving a comprehensive evaluation and histopathological confirmation, is crucial for effective management and prevention of unnecessary interventions. This case adds valuable insight into the clinical presentation, diagnostic challenges, and management strategies for soft-tissue chondromas.
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  • 文章类型: Journal Article
    骨外软骨瘤是不附着于骨骼或骨膜的小结节性软骨病变。它们是罕见的肿瘤,通常发生在手和脚。本研究的目的是描述左膝骨外肌内软骨瘤(EIC)的病例以及我们面临的诊断挑战。一名25岁的女性患者表现为左膝肿胀缓慢增长2年。临床上,肿胀是由股四头肌引起的。我们考虑了横纹肌瘤等可能性,神经纤维瘤,和肌内脂肪瘤.影像学检查提示良性脂肪瘤。她接受了切除治疗。显微镜检查与EIC一致,无复发。一个罕见的实体,临床上,EIC可以模拟其他良性软组织肿瘤。组织病理学检查可以提供明确的诊断。切除肿瘤是治愈性的。
    Extraskeletal chondromas are small nodular cartilaginous lesions not attached to bone or the periosteum. They are rare tumors commonly occurring in the hands and feet. The objective of the present study is to describe a case of extraskeletal intramuscular chondroma (EIC) in the left knee and the diagnostic challenges faced by us. A 25-year-old female patient presented with slow-growing swelling in the left knee for 2 years. Clinically, the swelling was arising from the quadriceps muscle. We considered possibilities such as rhabdomyoma, neurofibroma, and intramuscular lipoma. Imaging studies suggested a benign fatty tumor. She was treated by excision. Microscopy was consistent with EIC without recurrence. A rare entity, clinically, EIC can mimic other benign soft-tissue tumors. Histopathology exams can provide a definitive diagnosis. The excision of the tumor is curative.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    良性软组织软骨瘤是一种罕见的骨外软骨细胞肿瘤。它通常可以在四肢的骨骼系统中发现。头颈部是骨外软骨瘤最罕见的部位之一。最常见的站点是舌头,而其他子站点引起的病例很少。我们提出了一个56岁的绅士,他带着右咀嚼器空间膨胀来到我们的OPD。它对FNAC是非恶性的。他通过经腮腺入路进行了广泛的局部切除术。最终活检和IHC报告显示存在良性软骨细胞瘤-软组织软骨瘤(骨外)。没有使用进一步的治疗,此后一直在随访。据我们所知,这是第3例报道的咬肌间隙软骨瘤。
    在线版本包含补充材料,可在10.1007/s12070-023-03705-5获得。
    Benign soft tissue chondroma is a rare type of extraskeletal chondrocytic tumour. It usually can be found in skeletal system in extremities. Head and neck region is one of the most uncommon sites for extraskeletal chondroma .Most common site is tongue and there has been paucity of cases arising from the other subsites .We present a case of 56 years gentleman who came to our OPD with a right masticator space swelling. It was nonmalignant on FNAC. He underwent wide local excision through a transparotid approach. Final biopsy & IHC report showed presence of benign chondrocytic neoplasm- soft tissue chondroma (extraskeletal). No further therapy was used and he has been in follow up since then. To our knowledge ,this is the third reported case of masseteric space chondroma.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-023-03705-5.
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  • 文章类型: Review
    鼻软骨瘤和鼻非典型软骨肿瘤(或1级软骨肉瘤)是非常罕见的软骨源性肿瘤。已描述了大约150例鼻软骨瘤和少于50例的鼻非典型软骨肿瘤。我们报告了1例右侧筛窦区域的鼻软骨瘤和1例前间隔的鼻非典型软骨肿瘤。内镜下切除后17年无软骨瘤复发。通过面部中部脱套广泛手术切除36个月后,鼻腔非典型软骨肿瘤复发。通过面部中部脱套再次进行了翻修手术。鼻软骨瘤和非典型软骨肿瘤的复发极为罕见。目前的数据表明有足够的手术切除,在某些情况下甚至激进,作为避免复发的最重要参数。对于不能手术的非典型软骨肿瘤复发病例,可以观察。
    Nasal chondromas and nasal atypical cartilaginous tumors (or chondrosarcoma grade 1) are very rare chondrogenic tumors. Approximately 150 cases of nasal chondroma and fewer than 50 cases of nasal atypical cartilaginous tumors have been described. We reported a case with nasal chondroma in the right ethmoid area and a case with a nasal atypical cartilaginous tumor of the anterior septum. No chondroma recurrence was noted for 17 years after endoscopic resection. Recurrence was noted for the nasal atypical cartilaginous tumor 36 months after wide surgical excision via midfacial degloving. Revision surgery was performed again via midfacial degloving. Recurrences of nasal chondroma and atypical cartilaginous tumors are extremely rare. The current data indicate adequate surgical excision, in some cases even radical, as the most important parameter to avoid recurrence. For inoperable recurrent cases of atypical cartilaginous tumors, observation may be followed.
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  • 文章类型: Case Reports
    关节周围软骨瘤常见于肱骨和股骨,但很少发生在颞下颌关节。我们报告了一例耳前部的软骨瘤。在他访问前一年,一名53岁的男子意识到右脸颊区域的肿胀逐渐增加。在右耳的前部,有一个25毫米的肿瘤,弹性和坚硬,流动性差,没有压痛。对比增强计算机断层扫描CT显示腮腺上极有弥漫性钙化或骨化的肿块病变,内部对比度较差。磁共振成像显示腮腺有低信号肿块病变,T1和T2均有高信号。细针穿刺细胞学无法诊断。使用神经监测系统,用腮腺上极的正常组织切除肿瘤,方法与腮腺良性肿瘤相同。区分多形性腺瘤,包括腮腺的弥漫性微钙化和颞下颌关节的软骨肿瘤,有时可能很难。在这种情况下,手术切除可能是一个有益的治疗选择。
    Periarticular chondromas are common in the humerus and femur but rarely occur in the temporomandibular joint. We report a case of a chondroma in the anterior part of the ear. One year prior to his visit, a 53-year-old man became aware of swelling in the right cheek region which gradually increased in size. In the anterior part of the right ear, there was a palpable 25 mm tumor, elastic and hard, with poor mobility and without tenderness. A contrast-enhanced computed tomography CT showed a mass lesion with diffuse calcification or ossification in the upper pole of the parotid gland and areas of poor contrast within. A magnetic resonance imaging showed a low-signal mass lesion at the parotid gland with some high signals in both T1 and T2. Fine-needle aspiration cytology did not lead to diagnosis. Using a nerve monitoring system, the tumor was resected with normal tissue of the upper pole of the parotid gland in the same way as for a benign parotid tumor. Distinguishing between pleomorphic adenoma, including diffuse microcalcification of the parotid gland and cartilaginous tumors of the temporomandibular joint, may be sometimes difficult. In such cases, surgical resection may be a beneficial treatment option.
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  • 文章类型: Review
    背景:本研究旨在观察中期临床,使用骨镜辅助刮除和人工骨替代物或骨移植治疗的手部内生软骨瘤患者的功能和放射学结果。骨镜检查的添加允许在肿瘤组织刮除期间和之后直接可视化骨腔,而无需在骨皮质中形成大开口。这可以更好地清除肿瘤组织并降低医源性骨折的风险。方法:回顾性分析2013年12月至2020年11月收治的11例手术患者的临床资料。所有病例均有内生软骨瘤的组织学诊断。排除随访期少于3个月的患者。平均随访时间为20.9个月。对于临床结果,我们测量了总主动运动(TAM),并根据Belsky评分握力进行评分。对于功能结果,手臂的快速残疾,使用肩手问卷(QuickDASH)评分。对于放射学结果,我们评估了X线对骨腔充盈缺损,根据Tordai提出的系统,新骨形成。结果:患者的平均TAM为257º。共有60%的患者Belsky评分为优秀,40%患者Belsky评分分级良好。与对侧相比,握力的平均百分比为86.2%。QuickDASH平均得分为7.7。对于患者的伤口美学评级,81.8%的患者报告为优秀。对于放射学结果,所有患者术后X线片显示骨充填缺损小于3mm。完成骨巩固的平均时间为3.8个月。没有患者显示任何复发的放射学迹象。结论:我们的研究表明,用这种微创方法治疗的手部内生软骨瘤患者表现出良好的功能和放射学结果。它的应用还可以扩展到治疗手中的其他良性骨病变。证据级别:IV级(治疗)。
    Background: This study aims to look at the intermediate-term clinical, functional and radiological outcomes of patients with enchondroma in hand treated with osteoscopic-assisted curettage and artificial bone substitute or bone graft. The addition of osteoscopy allows direct visualisation of the bone cavity during and after curettage of tumour tissue without the need of creating a large opening in the bone cortex. This could lead to better clearance of tumour tissue and lower risk of iatrogenic fracture. Methods: A total of 11 patients who received surgery from December 2013 to November 2020 were retrospectively reviewed. All cases had histological diagnosis of enchondroma. Patients with a follow-up period of less than 3 months were excluded. The mean duration of follow-up was 20.9 months. For the clinical outcome, we measured the total active motion (TAM) and graded with Belsky score grip strength. For the functional outcome, the Quick Disabilities of the Arm, Shoulder and Hand Questionnaire (QuickDASH) score was used. For the radiological outcome, we evaluated the X-ray for bone cavity filling defect, new bone formation according to the system proposed by Tordai. Results: The mean TAM of patients was 257º. A total of 60% patients had Belsky score grading excellent, 40% patients had Belsky score grading good. The mean percentage of grip strength compared with the contralateral side was 86.2%. The mean QuickDASH score was 7.7. For the wound aesthetic rating by patients, 81.8% patients reported as excellent. For the radiological outcome, the postoperative X-ray of all patients showed bone filling defect less than 3 mm. The mean time to complete bone consolidation was 3.8 months. None of the patients showed any radiological signs of recurrence. Conclusions: Our study showed that patients with enchondromas in hand treated with this minimally invasive method demonstrated good functional and radiological outcome. Its application may also be extended into treating other benign bone lesions in hand. Level of Evidence: Level IV (Therapeutic).
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  • 文章类型: Systematic Review
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  • 文章类型: Case Reports
    肢端纤维软骨粘液样肿瘤是一种新描述的良性软组织肿瘤,表现为手指或脚趾上的单个结节性病变。以前只有一份关于这种肿瘤的报告,描述最初病理和临床发现的病例系列;然而,关于临床病史的细节,体检,结果未知。在这份报告中,我们描述了一例39岁的男性,他表现出疼痛性的肿物,涉及远端右三指和下甲。进行了穿刺活检,并在显微镜检查中将病变确定为肢端纤维软骨粘液样肿瘤。X线检查显示无骨性累及。成功切除肿瘤,疼痛症状完全缓解。在目前对这种非常罕见的肿瘤知识有限的背景下,我们讨论了我们病例的临床特征和免疫组织化学发现。
    An acral fibrochondromyxoid tumor is a newly described type of benign soft tissue neoplasm that presents as a single nodular lesion on a finger or toe. There has only been one previous report on this tumor, a case series that described the initial pathologic and clinical findings; however, details on clinical history, physical examination, and outcome are unknown. In this report, we describe a case of a 39-year-old male who presented with a painful enlarging mass involving the distal right 3rd finger and hyponychium. Punch biopsy was performed and the lesion was identified as an acral fibrochondromyxoid tumor on microscopic examination. X-ray showed no bony involvement. The tumor was successfully excised with complete resolution of pain symptoms. We discuss the clinical features and immunohistochemistry findings of our case in the context of the current limited knowledge about this very rare tumor.
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